Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PCNT anticorps (AA 1692-1814)

PCNT Reactivité: Souris WB, IF Hôte: Souris Monoclonal 30-Pericentrin unconjugated
N° du produit ABIN968666
  • Antigène Voir toutes PCNT Anticorps
    PCNT (Pericentrin (PCNT))
    Épitope
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1692-1814
    Reactivité
    • 11
    • 3
    • 1
    Souris
    Hôte
    • 12
    • 1
    Souris
    Clonalité
    • 12
    • 1
    Monoclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    Cet anticorp PCNT est non-conjugé
    Application
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Mouse pericentrin aa. 1692-1814
    Clone
    30-Pericentrin
    Isotype
    IgG1
    Top Product
    Discover our top product PCNT Anticorps primaire
  • Commentaires

    Related Products: ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20° C.
  • Arellano, Guadiana, Breunig, Rakic, Sarkisian: "Development and distribution of neuronal cilia in mouse neocortex." dans: The Journal of comparative neurology, Vol. 520, Issue 4, pp. 848-73, (2012) (PubMed).

    Young, Dictenberg, Purohit, Tuft, Doxsey: "Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes." dans: Molecular biology of the cell, Vol. 11, Issue 6, pp. 2047-56, (2000) (PubMed).

    Doxsey, Stein, Evans, Calarco, Kirschner: "Pericentrin, a highly conserved centrosome protein involved in microtubule organization." dans: Cell, Vol. 76, Issue 4, pp. 639-50, (1994) (PubMed).

  • Antigène
    PCNT (Pericentrin (PCNT))
    Autre désignation
    Pericentrin (PCNT Produits)
    Synonymes
    anticorps AKAP450, anticorps CG13459, anticorps CG18648, anticorps CG33957, anticorps CG6735, anticorps CP309, anticorps Cp309, anticorps D-PLP, anticorps DPLP, anticorps Dmel\\CG33957, anticorps Dplp, anticorps PACT, anticorps PLP, anticorps Plp, anticorps d-plp, anticorps dPLP, anticorps dplp, anticorps l(3)s2172, anticorps pPlp, anticorps KEN, anticorps MOPD2, anticorps PCN, anticorps PCNT2, anticorps PCNTB, anticorps PCTN2, anticorps SCKL4, anticorps DIP2A, anticorps AW476095, anticorps C86676, anticorps Pcnt2, anticorps kendrin, anticorps m239Asp, anticorps m275Asp, anticorps pericentrin, anticorps Pericentrin-like protein, anticorps pericentrin (kendrin), anticorps LOC100055203, anticorps Plp, anticorps PCNT, anticorps pcnt, anticorps Pcnt
    Sujet
    Centrosomes and other microtubule-organizing centers are a diverse group of organelles that nucleate and organize microtubules for many celllular processes, such as mitotic spindle formation, organelle tranpsort, and protein localization. Pericentrin is a protein in the pericentriolar material, a filamentous matrix surrounding centrioles, which can organize microtubule spindle formation. The structure of pericentrin includes multiple alpha-helical domains that form coiled-coil domains separated by non-helical, non-coiled regions. It is found in a 3 MDa-complex that includes gamma-tubulin, a form of tubulin that nucleates microtubule formation at the centrosome. Pericentrin exhibits the highest expression in embryonic mouse kidney, thymus, and liver. Injection of pericentrin antibodies in Xenopus oocytes disrupts mitotic and meiotic divisions and blocks microtubule aster formation. In addition, dynein transports both pericentrin and gamma-tubulin to centrosomes along microtubules in Xenopus oocyte extracts. Thus, the complex of pericentrin and gamma-tubulin may be recruited to the centrosome by dynein, where the complex becomes anchored to the centrosome for microtubule nucleating activity. This antibody is routinely tested by western blot analysis.
    Poids moléculaire
    220 kDa
    Pathways
    Sensory Perception of Sound, M Phase, SARS-CoV-2 Protein Interactome
Vous êtes ici:
Support technique