Phosphoserine anticorps

N° du produit ABIN968871

Détail du produit anti-Phosphoserine anticorps

Antigène: Phosphoserine

Reactivité: Veuillez nous consulter SVP

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Phosphoserine est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 19-pSer

Isotype: IgG1

Information d'application

Indications d'application: Western blot: Typically, 1:2500 is a useful dilution for use in Western Blot.

Commentaires:

Related Products: ABIN968887, ABIN967389, ABIN968871

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-Phosphoserine (ABIN968871)

Brivanlou, Darnell: "Signal transduction and the control of gene expression." dans: Science (New York, N.Y.), Vol. 295, Issue 5556, pp. 813-8, (2002) (PubMed).

Pawson, Scott: "Signaling through scaffold, anchoring, and adaptor proteins." dans: Science (New York, N.Y.), Vol. 278, Issue 5346, pp. 2075-80, (1998) (PubMed).

Yan, Packer, Gooley, Williams: "Protein phosphorylation: technologies for the identification of phosphoamino acids." dans: Journal of chromatography. A, Vol. 808, Issue 1-2, pp. 23-41, (1998) (PubMed).

Détails sur Phosphoserine

Antigène: Phosphoserine

Abstract: Phosphoserine Produits

Classe de substances: Amino Acid

Sujet: Protein phosphorylation of serine and threonine residues is critical for the control of protein activity involved in various cellular events. An assortment of Ser/Thr kinases and phosphatases regulate serine and threonine phosphorylation in cell signaling pathways, such as growth factor, cytokine, chemokine, and stress response. Detection of serine and threonine phosphorylation can generally be monitored by antibodies that detect phosphoserine and phosphothreonine. Our clone 19 antibody specifically recognizes phosphoserine modifications on peptides in ELISA, while our clone 22a detects both phosphoserine and phosphothreonine modifications on peptides in ELISA. These antibodies are reported to be useful for Western blot, flow cytometry, and microscopy detection of phosphoserine and phosphothreonine levels.