Phosphoserine/Threonine anticorps

N° du produit ABIN968874

Détail du produit

Antigène: Phosphoserine/Threonine

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 22A-pSer-Thr

Isotype: IgG1

Information d'application

Indications d'application: For western blotting, a dilution of 1:2500 may be a useful starting concentration for titrations.

Commentaires:

Related Products: ABIN968533, ABIN968887, ABIN967389, ABIN968871

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Référence

Brivanlou, Darnell: "Signal transduction and the control of gene expression." dans: Science (New York, N.Y.), Vol. 295, Issue 5556, pp. 813-8, (2002) (PubMed).

Pawson, Scott: "Signaling through scaffold, anchoring, and adaptor proteins." dans: Science (New York, N.Y.), Vol. 278, Issue 5346, pp. 2075-80, (1998) (PubMed).

Yan, Packer, Gooley, Williams: "Protein phosphorylation: technologies for the identification of phosphoamino acids." dans: Journal of chromatography. A, Vol. 808, Issue 1-2, pp. 23-41, (1998) (PubMed).

Détail du antigène

Antigène: Phosphoserine/Threonine

Sujet: Protein phosphorylation of serine and threonine residues is critical for the control of protein activity involved in various cellular events. An assortment of Ser/Thr kinases and phosphatases regulate serine and threonine phosphorylation in cell signaling pathways, such as growth factor, cytokine, chemokine, and stress response. Detection of serine and threonine phosphorylation can generally be monitored by antibodies that detect phosphoserine and phosphothreonine.