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APOE anticorps

APOE Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 1H4 unconjugated
N° du produit ABIN968962
  • Antigène Voir toutes APOE Anticorps
    APOE (Apolipoprotein E (APOE))
    Reactivité
    • 101
    • 75
    • 56
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 103
    • 21
    • 13
    • 2
    Souris
    Clonalité
    • 105
    • 33
    Monoclonal
    Conjugué
    • 59
    • 18
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp APOE est non-conjugé
    Application
    • 110
    • 56
    • 39
    • 39
    • 29
    • 25
    • 20
    • 12
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ApoE expressed in E. coli.
    Clone
    1H4
    Isotype
    IgG1
    Top Product
    Discover our top product APOE Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Karpouzis, Caridha, Tripsianis, Michailidis, Martinis, Veletza: "Apolipoprotein E gene polymorphism in psoriasis." dans: Archives of dermatological research, Vol. 301, Issue 6, pp. 405-10, (2009) (PubMed).

    Zintzaras, Kitsios, Triposkiadis, Lau, Raman: "APOE gene polymorphisms and response to statin therapy." dans: The pharmacogenomics journal, Vol. 9, Issue 4, pp. 248-57, (2009) (PubMed).

  • Antigène
    APOE (Apolipoprotein E (APOE))
    Autre désignation
    ApoE (APOE Produits)
    Synonymes
    anticorps ad2, anticorps apoprotein, anticorps im:7036787, anticorps wu:fb69a05, anticorps zgc:110064, anticorps apoe, anticorps AI255918, anticorps AD2, anticorps LDLCQ5, anticorps LPG, anticorps APOEA, anticorps Apo-E, anticorps apolipoprotein E, anticorps apolipoprotein Ea, anticorps apoe, anticorps apoea, anticorps Apoe, anticorps APOE
    Sujet

    Description: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Tissue specificity: Occurs in all lipoprotein fractions in plasma. It constitutes 10-20 % of very low density lipoproteins (VLDL) and 1-2 % of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.

    Aliases: AD2, LPG, LDLCQ5, MGC1571

    Poids moléculaire
    36 kDa
    ID gène
    348
    HGNC
    348
    Pathways
    Regulation of Cell Size, Lipid Metabolism
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