CDK9 anticorps

N° du produit ABIN969042

Détail du produit anti-CDK9 anticorps

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human CDK9 expressed in E. coli.

Clone: 1B5A7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-CDK9 (ABIN969042)

Montanuy, Torremocha, Hernández-Munain, Suñé: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." dans: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).

Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." dans: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

Détails sur CDK9

Antigène: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Autre désignation: CDK9 (CDK9 Produits)

Synonymes: anticorps C-2k, anticorps CDC2L4, anticorps CTK1, anticorps PITALRE, anticorps TAK, anticorps wu:fb22e09, anticorps wu:fc06c02, anticorps c-2k, anticorps cdc2l4, anticorps cdk9, anticorps ctk1, anticorps pitalre, anticorps tak, anticorps CDK9, anticorps CG5179, anticorps Dmel\\CG5179, anticorps P-TEF, anticorps P-TEFb, anticorps PTefb, anticorps cyclin dependent kinase 9, anticorps cyclin-dependent kinase 9 (CDC2-related kinase), anticorps cyclin-dependent kinase 9 L homeolog, anticorps cyclin-dependent kinase 9, anticorps Cyclin-dependent kinase 9, anticorps cyclin-dependent kinase 9 S homeolog, anticorps CDK9, anticorps cdk9, anticorps cdk9.L, anticorps Cdk9, anticorps cdk9.S

Sujet:

Description: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

Aliases: TAK, C-2k, CTK1, CDC2L4, PITALRE

Poids moléculaire: 43 kDa

ID gène: 1025

HGNC: 1025

Pathways: Cycle Cellulaire