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KRT8 anticorps (AA 391-483)

Name: KRT8 anticorps (AA 391-483)
Brand: antibodies-online
SKU: ABIN969080
Price: 661.53 EUR
Availability: InStock

KRT8 Reactivité: Humain WB, IHC, ELISA, ICC Hôte: Souris Monoclonal 8A5D12 unconjugated

Immunohistochemical analysis of paraffin-embedded human Kidney tissues using CK8 mouse mAb

IHC

Confocal immunofluorescence analysis of methanol-fixed ECA109 cells (left) and HepG2 cells (right) using CK8 mouse mAb (green), showing cytoplasmic localization.

Western blot analysis using CK8 mouse mAb against A549 (1), Hela (2), MCF-7 (3), A431 (4) and HepG2 (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), lung cancer (B) and ovarian cancer tissue (C), showing membrane and cytoplasmic localization with DAB staining using CK8 mouse mAb.

IHC

4 images

(1 reference)

N° du produit ABIN969080

Fiche de données

Antigène Voir toutes KRT8 Anticorps

KRT8 (Keratin 8 (KRT8))
Épitope
18

16

13

12

10

6

6

5

4

4

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-483
Reactivité
247

81

76

32

32

30

30

16

14

10

7

4

4

2

2

1

1

1
Humain
Hôte
132

124

2

1
Souris
Anticorps secondaires appropriés
Clonalité
129

128
Monoclonal
Conjugué
137

23

17

9

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

1
Cet anticorp KRT8 est non-conjugé
Application
163

97

88

83

66

50

41

40

31

29

23

18

5

5

4

4

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification

purified

Immunogène

Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. coli.

Clone

8A5D12

Isotype

IgG1

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Indications d'application

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

4°C, -20°C for long term storage
Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." dans: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
Antigène

KRT8 (Keratin 8 (KRT8))

Autre désignation

Cytokeratin 8 (KRT8 Produits)

Synonymes

anticorps CARD2, anticorps CK-8, anticorps CK8, anticorps CYK8, anticorps K2C8, anticorps K8, anticorps KO, anticorps AA960620, anticorps AL022697, anticorps AU019895, anticorps Card2, anticorps EndoA, anticorps Krt-2.8, anticorps Krt2-8, anticorps CYKER, anticorps KRT2-8, anticorps KERATIN8, anticorps ck8, anticorps cyk8, anticorps k2c8, anticorps card2, anticorps krt2-5, anticorps MGC69490, anticorps KRT8, anticorps DreK8, anticorps cb186, anticorps krt2-8, anticorps sb:cb186, anticorps wu:fa20h05, anticorps wu:fa95h10, anticorps wu:fb96c06, anticorps zf-K8, anticorps zfk8, anticorps DKFZp468F2127, anticorps keratin 8, anticorps keratin 8 S homeolog, anticorps KRT8, anticorps Krt8, anticorps krt8.S, anticorps krt8

Sujet

Description: Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Aliases: CK8, CYK8, K2C8, KRT8

Poids moléculaire

54 kDa

ID gène

3856

HGNC

3856