p300 anticorps

N° du produit ABIN969098

Détail du produit anti-p300 anticorps

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p300 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of EP300 expressed in E. coli.

Clone: 7D8A6

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-p300 (ABIN969098)

Geiger, Sharma, Kim, Nyborg: "The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB." dans: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008) (PubMed).

Stauffer, Chang, Huang, Dunn, Thayer: "p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint." dans: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9678-87, (2007) (PubMed).

Détails sur p300

Antigène: p300 (EP300) (E1A Binding Protein P300 (EP300))

Autre désignation: EP300 (EP300 Produits)

Synonymes: anticorps KAT3B, anticorps RSTS2, anticorps p300, anticorps A430090G16, anticorps A730011L11, anticorps p300 HAT, anticorps E1A binding protein p300, anticorps histone acetyltransferase p300, anticorps EP300, anticorps LOC446056, anticorps ep300, anticorps Ep300

Sujet:

Description: EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Aliases: p300, KAT3B

ID gène: 2033

HGNC: 2033

Pathways: Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size