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Fibulin 5 anticorps (AA 242-448)

FBLN5 Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 1G6A4 unconjugated
N° du produit ABIN969131
  • Antigène Voir toutes Fibulin 5 (FBLN5) Anticorps
    Fibulin 5 (FBLN5)
    Épitope
    • 12
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-448
    Reactivité
    • 52
    • 30
    • 23
    • 1
    Humain
    Hôte
    • 52
    • 5
    • 1
    Souris
    Clonalité
    • 53
    • 7
    Monoclonal
    Conjugué
    • 27
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Fibulin 5 est non-conjugé
    Application
    • 55
    • 31
    • 14
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. coli.
    Clone
    1G6A4
    Isotype
    IgG1
    Top Product
    Discover our top product FBLN5 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." dans: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." dans: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

    Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." dans: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

  • Antigène
    Fibulin 5 (FBLN5)
    Autre désignation
    FBLN5 (FBLN5 Produits)
    Synonymes
    anticorps zgc:103575, anticorps FBLN5, anticorps MGC108414, anticorps Fibulin-5, anticorps DKFZp469K0327, anticorps ADCL2, anticorps ARCL1A, anticorps ARMD3, anticorps DANCE, anticorps EVEC, anticorps FIBL-5, anticorps UP50, anticorps A55, anticorps fibulin 5, anticorps fbln5, anticorps FBLN5, anticorps Fbln5
    Sujet

    Description: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

    Aliases: EVEC, UP50, ARMD3, DANCE

    ID gène
    10516
    HGNC
    10516
    Pathways
    SARS-CoV-2 Protein Interactome
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