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HDAC4 anticorps

HDAC4 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 7B2 unconjugated
N° du produit ABIN969190
  • Antigène Voir toutes HDAC4 Anticorps
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Reactivité
    • 115
    • 52
    • 35
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 104
    • 12
    • 1
    Souris
    Clonalité
    • 104
    • 13
    Monoclonal
    Conjugué
    • 73
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HDAC4 est non-conjugé
    Application
    • 89
    • 50
    • 29
    • 16
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human HDAC4 expressed in E. coli.
    Clone
    7B2
    Isotype
    IgG1
    Top Product
    Discover our top product HDAC4 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Shao, Li, Zhang, Liu, Liu, Zhao, Shen, Li: "Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX." dans: Nucleic acids research, Vol. 38, Issue 9, pp. 2813-24, (2010) (PubMed).

    Ficner: "Novel structural insights into class I and II histone deacetylases." dans: Current topics in medicinal chemistry, Vol. 9, Issue 3, pp. 235-40, (2009) (PubMed).

    Nishino, Miyazaki, Hoshino, Miwa, Horinouchi, Yoshida: "14-3-3 regulates the nuclear import of class IIa histone deacetylases." dans: Biochemical and biophysical research communications, Vol. 377, Issue 3, pp. 852-6, (2008) (PubMed).

  • Antigène
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Autre désignation
    HDAC4 (HDAC4 Produits)
    Synonymes
    anticorps CG1770, anticorps DHDAC4, anticorps Dmel\\CG1770, anticorps GC1770, anticorps HDAC, anticorps HDAC4a, anticorps dHDAC4, anticorps dmHDA405, anticorps hdac4, anticorps dana_GLEANR_19966, anticorps DanaGF18710, anticorps GF18710, anticorps HDAC4, anticorps AHO3, anticorps BDMR, anticorps HA6116, anticorps HD4, anticorps HDAC-4, anticorps HDAC-A, anticorps HDACA, anticorps 4932408F19Rik, anticorps AI047285, anticorps wu:fa96d08, anticorps wu:fc56f08, anticorps zgc:152701, anticorps histone deacetylase 4, anticorps hypothetical protein, anticorps Histone deacetylase 4, anticorps GF18710 gene product from transcript GF18710-RC, anticorps PTRG_03699, anticorps PGTG_15512, anticorps HDAC4, anticorps Dana\GF18710, anticorps Hdac4, anticorps hdac4
    Sujet

    Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

    Aliases: HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4

    Poids moléculaire
    119 kDa
    ID gène
    9759
    HGNC
    9759
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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