ITK anticorps
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- Antigène Voir toutes ITK Anticorps
- ITK (IL2-Inducible T-Cell Kinase (ITK))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ITK est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ITK expressed in E. coli.
- Clone
- 5G6
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." dans: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." dans: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).
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Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." dans: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).
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- Antigène
- ITK (IL2-Inducible T-Cell Kinase (ITK))
- Autre désignation
- ITK (ITK Produits)
- Synonymes
- anticorps Emt, anticorps Tcsk, anticorps Tsk, anticorps EMT, anticorps LPFS1, anticorps LYK, anticorps PSCTK2, anticorps IL2 inducible T cell kinase, anticorps IL2 inducible T-cell kinase, anticorps IL2-inducible T-cell kinase, anticorps Itk, anticorps ITK
- Sujet
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Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258
- Poids moléculaire
- 72 kDa
- ID gène
- 3702
- HGNC
- 3702
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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