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ITK anticorps

ITK Reactivité: Humain WB, ELISA, ICC, FACS Hôte: Souris Monoclonal 5G6 unconjugated
N° du produit ABIN969222
  • Antigène Voir toutes ITK Anticorps
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Reactivité
    • 51
    • 20
    • 12
    • 6
    • 3
    Humain
    Hôte
    • 63
    • 5
    • 2
    Souris
    Clonalité
    • 64
    • 6
    Monoclonal
    Conjugué
    • 31
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITK est non-conjugé
    Application
    • 43
    • 36
    • 14
    • 12
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ITK expressed in E. coli.
    Clone
    5G6
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." dans: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

    Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." dans: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

  • Antigène
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Autre désignation
    ITK (ITK Produits)
    Synonymes
    anticorps Emt, anticorps Tcsk, anticorps Tsk, anticorps EMT, anticorps LPFS1, anticorps LYK, anticorps PSCTK2, anticorps IL2 inducible T cell kinase, anticorps IL2 inducible T-cell kinase, anticorps IL2-inducible T-cell kinase, anticorps Itk, anticorps ITK
    Sujet

    Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258

    Poids moléculaire
    72 kDa
    ID gène
    3702
    HGNC
    3702
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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