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NFKBIB anticorps

NFKBIB Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 7B4 unconjugated
N° du produit ABIN969314
  • Antigène Voir toutes NFKBIB Anticorps
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Reactivité
    • 107
    • 41
    • 35
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 101
    • 7
    Souris
    Clonalité
    • 93
    • 15
    Monoclonal
    Conjugué
    • 54
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp NFKBIB est non-conjugé
    Application
    • 80
    • 38
    • 30
    • 24
    • 23
    • 16
    • 13
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human NFKBIB expressed in E. coli.
    Clone
    7B4
    Isotype
    IgG1
    Top Product
    Discover our top product NFKBIB Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

    Chen, Vallee, Wu, Vu, Sondek, Ghosh: "Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras." dans: Molecular and cellular biology, Vol. 24, Issue 7, pp. 3048-56, (2004) (PubMed).

    Abid, Schoots, Spokes, Wu, Mawhinney, Aird: "Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB." dans: The Journal of biological chemistry, Vol. 279, Issue 42, pp. 44030-8, (2004) (PubMed).

  • Antigène
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Autre désignation
    NFKBIB (NFKBIB Produits)
    Synonymes
    anticorps NFKBIB, anticorps IKB-beta, anticorps IKappaBbeta, anticorps IkB, anticorps IkBb, anticorps IKBB, anticorps TRIP9, anticorps NFKB inhibitor beta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta, anticorps NFKBIB, anticorps Nfkbib
    Sujet

    Description: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

    Aliases: IKBB, TRIP9, NFKBIB

    Poids moléculaire
    45 kDa
    ID gène
    4793
    HGNC
    4793
    Pathways
    Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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