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Progesterone Receptor anticorps (AA 730-871)

PGR Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 8A11H1 unconjugated
N° du produit ABIN969352
  • Antigène Voir toutes Progesterone Receptor (PGR) Anticorps
    Progesterone Receptor (PGR)
    Épitope
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    AA 730-871
    Reactivité
    • 239
    • 42
    • 38
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    • 8
    • 6
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    • 5
    • 3
    • 3
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    • 1
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    Humain
    Hôte
    • 182
    • 59
    • 1
    • 1
    Souris
    Clonalité
    • 176
    • 67
    Monoclonal
    Conjugué
    • 120
    • 21
    • 11
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    • 2
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    • 1
    Cet anticorp Progesterone Receptor est non-conjugé
    Application
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    • 57
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    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of PGR (aa730-871) expressed in E. coli.
    Clone
    8A11H1
    Isotype
    IgG1
    Top Product
    Discover our top product PGR Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • LEplattenier, Lai, van den Ham, Mol, van Sluijs, Teske: "Regulation of COX-2 expression in canine prostate carcinoma: increased COX-2 expression is not related to inflammation." dans: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, Vol. 21, Issue 4, pp. 776-82, (2007) (PubMed).

    Yin, Lin, Cheng, Marsh, Utsunomiya, Ishikawa, Xue, Reierstad, Innes, Thung, Kim, Xu, Bulun: "Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells." dans: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 11, pp. 4459-66, (2007) (PubMed).

    Saito, Ito, Nagase, Suzuki, Akahira, Okamura, Yaegashi, Sasano: "Progesterone receptor isoforms as a prognostic marker in human endometrial carcinoma." dans: Cancer science, Vol. 97, Issue 12, pp. 1308-14, (2006) (PubMed).

    Tung, Abdel-Hafiz, Shen, Harvell, Nitao, Richer, Sartorius, Takimoto, Horwitz: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." dans: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, (2006) (PubMed).

    Buser, Gass-Handel, Wyszomierski, Doppler, Leonhardt, Schaack, Rosen, Watkin, Anderson, Edwards: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, (2006) (PubMed).

  • Antigène
    Progesterone Receptor (PGR)
    Autre désignation
    PGR (PGR Produits)
    Synonymes
    anticorps NR3C3, anticorps PR, anticorps 9930019P03Rik, anticorps BB114106, anticorps ENSMUSG00000074510, anticorps PR-A, anticorps PR-B, anticorps XPR-1, anticorps pgr, anticorps xpr-2, anticorps LOC443444, anticorps PGR, anticorps pg, anticorps pr, anticorps gb:dq017620, anticorps progesterone receptor, anticorps progesterone receptor L homeolog, anticorps PGR, anticorps Pgr, anticorps pgr.L, anticorps pgr
    Sujet

    Description: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.

    Aliases: PR, NR3C3, PGR

    ID gène
    5241
    HGNC
    5241
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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