PTK7 anticorps

N° du produit ABIN969374

Détail du produit anti-PTK7 anticorps

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTK7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human PTK7 expressed in E. coli.

Clone: 4F9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-PTK7 (ABIN969374)

Shin, Maeng, Jung, Min, Kwon, Lee: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." dans: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).

Détails sur PTK7

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Autre désignation: PTK7 (PTK7 Produits)

Synonymes: anticorps PTK7, anticorps CCK-4, anticorps CCK4, anticorps Srf, anticorps 8430404F20Rik, anticorps chz, anticorps mPTK7/CCK4, anticorps KLG, anticorps protein tyrosine kinase 7 (inactive), anticorps protein tyrosine kinase 7, anticorps PTK7 protein tyrosine kinase 7, anticorps PTK7, anticorps Ptk7

Sujet:

Description: Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Aliases: CCK4, PTK7

Poids moléculaire: 118 kDa

ID gène: 5754

HGNC: 5754

Pathways: Signalisation RTK, Tube Formation