SOX2 anticorps (AA 1-170)

N° du produit ABIN969413

Détail du produit anti-SOX2 anticorps

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Épitope: AA 1-170

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of SOX2 (aa1-170) expressed in E. coli.

Clone: 10F10C9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-SOX2 (ABIN969413)

Park, Zhao, West, Yabuuchi, Huo, Ince, Lerou, Lensch, Daley: "Reprogramming of human somatic cells to pluripotency with defined factors." dans: Nature, Vol. 451, Issue 7175, pp. 141-6, (2008) (PubMed).

Baer, Eriksson, Faull, Rees, Curtis: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." dans: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, (2007) (PubMed).

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2 (SOX2 Produits)

Synonymes: anticorps ANOP3, anticorps MCOPS3, anticorps RGD1565646, anticorps Sox-2, anticorps lcc, anticorps ysb, anticorps cb236, anticorps wu:fb83g04, anticorps wu:fc14d07, anticorps zgc:65860, anticorps zgc:77389, anticorps SRY-box2, anticorps Xsox-2, anticorps anop3, anticorps mcops3, anticorps sox-2, anticorps SRY-box 2, anticorps SRY box 2, anticorps SRY (sex determining region Y)-box 2, anticorps SRY-box 2 S homeolog, anticorps SOX2, anticorps Sox2, anticorps sox2, anticorps sox2.S

Sujet:

Description: SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Aliases: ANOP3, MCOPS3, MGC2413

Poids moléculaire: 34.3 kDa

ID gène: 6657

HGNC: 6657

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis