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Vimentin anticorps

VIM Reactivité: Humain WB, IHC, ELISA Hôte: Souris Monoclonal 9E7E7 unconjugated
N° du produit ABIN969453
  • Antigène Voir toutes Vimentin (VIM) Anticorps
    Vimentin (VIM)
    Reactivité
    • 334
    • 127
    • 126
    • 61
    • 59
    • 44
    • 43
    • 37
    • 30
    • 22
    • 20
    • 14
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 190
    • 130
    • 9
    • 6
    • 4
    • 4
    • 2
    Souris
    Clonalité
    • 198
    • 146
    Monoclonal
    Conjugué
    • 201
    • 19
    • 13
    • 13
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Vimentin est non-conjugé
    Application
    • 283
    • 132
    • 100
    • 99
    • 96
    • 65
    • 49
    • 40
    • 39
    • 28
    • 23
    • 20
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of Vimentin expressed in E. coli.
    Clone
    9E7E7
    Isotype
    IgG1
    Top Product
    Discover our top product VIM Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
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  • Antigène
    Vimentin (VIM)
    Autre désignation
    Vimentin (VIM Produits)
    Synonymes
    anticorps CTRCT30, anticorps cb28, anticorps vime, anticorps vim, anticorps vim1, anticorps vim2, anticorps VIM, anticorps Vimentin, anticorps vim4, anticorps vimentin, anticorps vimentin L homeolog, anticorps vimentin S homeolog, anticorps VIM, anticorps Vim, anticorps vim, anticorps vim.L, anticorps vim.S
    Sujet

    Description: Vimentin is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis. Immunohistochemical staining for Vimentin is characteristic of sarcomas (of neural, muscle and fibroblast origin) compared to carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin antibodies are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors. They are generally used with a panel of other antibodies including those recognising cytokeratins, lymphoid markers, S100, desmin and neurofilaments.

    Aliases: FLJ36605, VIM

    ID gène
    7431
    HGNC
    7431
    Pathways
    Caspase Cascade in Apoptosis
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