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WDR5 anticorps

WDR5 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 7B11 unconjugated
N° du produit ABIN969456
  • Antigène Voir toutes WDR5 Anticorps
    WDR5 (WD Repeat Domain 5 (WDR5))
    Reactivité
    • 66
    • 34
    • 26
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 60
    • 5
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 52
    • 15
    • 1
    Monoclonal
    Conjugué
    • 38
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp WDR5 est non-conjugé
    Application
    • 43
    • 31
    • 11
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human WDR5 expressed in E. coli.
    Clone
    7B11
    Isotype
    IgG2b
    Top Product
    Discover our top product WDR5 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." dans: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Antigène
    WDR5 (WD Repeat Domain 5 (WDR5))
    Autre désignation
    WDR5 (WDR5 Produits)
    Synonymes
    anticorps BIG-3, anticorps SWD3, anticorps 2410008O07Rik, anticorps AA408785, anticorps AA960360, anticorps Big, anticorps Big-3, anticorps zgc:56591, anticorps zgc:76895, anticorps wu:fk47f04, anticorps wdr5-a, anticorps MGC80538, anticorps wdr5-b, anticorps MGC81485, anticorps big-3, anticorps swd3, anticorps xwdr5, anticorps WDR5B, anticorps WD repeat domain 5, anticorps WD repeat domain 5 L homeolog, anticorps WD repeat domain 5 S homeolog, anticorps WDR5, anticorps Wdr5, anticorps wdr5, anticorps wdr5.L, anticorps wdr5.S
    Sujet

    Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

    Aliases: SWD3, BIG-3, WDR5

    Poids moléculaire
    36.6 kDa
    ID gène
    11091
    HGNC
    11091
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