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CYP1A1 anticorps

CYP1A1 Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 6G5 unconjugated
N° du produit ABIN969511
  • Antigène Voir toutes CYP1A1 Anticorps
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    Reactivité
    • 53
    • 25
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 37
    • 23
    • 1
    Souris
    Clonalité
    • 40
    • 21
    Monoclonal
    Conjugué
    • 39
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYP1A1 est non-conjugé
    Application
    • 47
    • 26
    • 16
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CYP1A1 expressed in E. coli.
    Clone
    6G5
    Isotype
    IgG1
    Top Product
    Discover our top product CYP1A1 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: "Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ..." dans: Cancer research, Vol. 69, Issue 7, pp. 2956-65, (2009) (PubMed).

    Breuer, Schmidt, Schuphan: "Utility of Nicotiana tabacum cell suspension cultures expressing human CYP1A1, CYP1A2 and CYP3A4 to study the oxidative metabolism of the herbicide 14C-fluometuron." dans: Drug metabolism letters, Vol. 3, Issue 1, pp. 18-27, (2009) (PubMed).

  • Antigène
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    Autre désignation
    CYP1A1 (CYP1A1 Produits)
    Synonymes
    anticorps AHH, anticorps AHRR, anticorps CP11, anticorps CYP1, anticorps P1-450, anticorps P450-C, anticorps P450DX, anticorps Cyp1a2, anticorps P450-1, anticorps cyp1a1, anticorps CYP1A1, anticorps CYPIA1, anticorps Cyp45c, anticorps Cypc45c, anticorps P-450MC, anticorps wu:fb63b04, anticorps zfCYP1A, anticorps zgc:109747, anticorps ahh, anticorps ahrr, anticorps cp11, anticorps cyp1, anticorps cyp1a, anticorps p1-450, anticorps p450-c, anticorps p450dx, anticorps cytochrome P450 family 1 subfamily A member 1, anticorps cytochrome P450 1A1, anticorps cytochrome P450, family 1, subfamily a, polypeptide 1, anticorps cytochrome P450, family 1, subfamily A, polypeptide 1, anticorps cytochrome P450 family 1 subfamily D polypeptide 1, anticorps cytochrome P4501A1, anticorps polycyclic hydrocarbon-inducible cytochrome P450c, anticorps cytochrome P450, family 1, subfamily A, anticorps cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1, anticorps cytochrome P450 family 1 subfamily A member 1 L homeolog, anticorps CYP1A1, anticorps CpipJ_CPIJ010542, anticorps Cyp1a1, anticorps cyp1d1, anticorps LOC100328613, anticorps cyp1a, anticorps LOC102129994, anticorps cyp1a1.L
    Sujet

    Description: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

    Aliases: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX

    Poids moléculaire
    58 kDa
    ID gène
    1543
    HGNC
    1543
    Pathways
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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