GRIA2 anticorps (AA 652-807)

N° du produit ABIN969524

Détail du produit anti-GRIA2 anticorps

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Épitope: AA 652-807

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. coli. ,

Clone: 7G6

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-GRIA2 (ABIN969524)

Yu, Wu, Fu, Cheng, Yang, Chen, Long, Chen, Wang: "Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus." dans: Neuroscience letters, Vol. 497, Issue 1, pp. 42-5, (2011) (PubMed).

Shen, Jin: "[GluR2 expression in the developing rat inferior colliculus and the relationship with development of synapse]." dans: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, Vol. 24, Issue 4, pp. 173-6, (2010) (PubMed).

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: GRIA2 (GRIA2 Produits)

Synonymes: anticorps GLUR2, anticorps GLURB, anticorps GluA2, anticorps GluR-K2, anticorps HBGR2, anticorps GluR-2, anticorps GluR-B, anticorps Glur-2, anticorps Glur2, anticorps GluR2, anticorps gluR-B, anticorps glur2a, anticorps gria2.1, anticorps zfGRIA2[a], anticorps glur2, anticorps glutamate ionotropic receptor AMPA type subunit 2, anticorps glutamate receptor, ionotropic, AMPA 2, anticorps glutamate receptor, ionotropic, AMPA2 (alpha 2), anticorps glutamate receptor, ionotropic, AMPA 2a, anticorps glutamate receptor, ionotropic, AMPA 2 S homeolog, anticorps GRIA2, anticorps Gria2, anticorps gria2a, anticorps gria2.S

Sujet:

Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Aliases: GluA2, GluR2, gluR-B, GluR-K2

Poids moléculaire: 98.8 kDa

ID gène: 29627

HGNC: 29627

Pathways: Signalisation PI3K-Akt