LRP5 anticorps (Low Density Lipoprotein Receptor-Related Protein 5)

Details for Product anti-LRP5 Antibody No. ABIN969535, Fournisseur: Connectez-vous pour afficher
Antigène
  • Xlrp5
  • bmnd1
  • evr1
  • evr4
  • hbm
  • lr3
  • lrp5-A
  • lrp7
  • oppg
  • ops
  • opta1
  • vbch2
  • LRP5
  • LRP6
  • BMND1
  • EVR1
  • EVR4
  • HBM
  • LR3
  • LRP7
  • OPPG
  • OPS
  • OPTA1
  • VBCH2
  • mKIAA4142
  • low density lipoprotein receptor-related protein 5
  • LRP5
  • lrp5
  • LOC100220027
  • Lrp5
Reactivité
Humain
105
82
49
3
2
1
1
1
1
Hôte
Souris
98
16
11
2
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp LRP5 est non-conjugé
8
8
7
5
5
5
3
3
3
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
81
60
36
29
14
6
5
4
2
2
2
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène Purified recombinant fragment of human LRP5 expressed in E. Coli.
Clone 2B11
Isotype IgG1
Purification Purified
Autre désignation LRP5 (LRP5 Antibody Extrait)
Sujet This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Poids moléculaire 179 kDa
ID gène 4041
HGNC 4041
Domaine de recherche Stem Cells, Wnt, Extracellular Matrix
Pathways Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibody (ABIN969535) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibody (ABIN969535) Figure 2: Flow cytometric analysis of HeLa cells using LRP5 mouse mAb (green) and neg...
Western Blotting (WB) image for anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibody (ABIN969535) Figure 3: Western blot analysis using LRP5 mAb against human LRP5 (AA: 1422-1615) rec...
Produit citée dans: Saarinen, Mäyränpää, Lehesjoki, Mäkitie: "Low-density lipoprotein receptor-related protein 5 (LRP5) variation in fracture prone children." dans: Bone, Vol. 46, Issue 4, pp. 940-5, 2010 (PubMed).

Urano, Shiraki, Usui, Sasaki, Ouchi, Inoue: "A1330V variant of the low-density lipoprotein receptor-related protein 5 (LRP5) gene decreases Wnt signaling and affects the total body bone mineral density in Japanese women." dans: Endocrine journal, Vol. 56, Issue 4, pp. 625-31, 2009 (PubMed).

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