MMP3 anticorps

N° du produit ABIN969539

Détail du produit anti-MMP3 anticorps

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human MMP3 expressed in E. coli.

Clone: 4F10

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-MMP3 (ABIN969539)

Jin, Miao, Hu, Xu, Huang, Chen, Tian, Wei, Boffetta, Shen: "Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population." dans: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 2172-8, (2009) (PubMed).

Nan, Niu, Hunter, Han: "Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3551-7, (2008) (PubMed).

Détails sur MMP3

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Autre désignation: MMP3 (MMP3 Produits)

Sujet:

Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Aliases: SL-1, STMY, STR1, CHDS6, MMP-3, STMY1

Poids moléculaire: 54 kDa

ID gène: 4314

HGNC: 4314