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Détail du produit
anti-c-erb-2 anticorps
Aperçu
| Antigène: | C-erb-2 |
| Clonalité: | Monoclonal (CB11) |
| Application: | Immunohistochemistry (IHC) |
| Reactivité: | Human |
| Hôte: | Mouse |
|
1 référence disponible |
| Quantité: | |
| Prix: | 279,00 € (Plus frais de livraison et TVA) |
| Numéro du produit: | ABIN97147 |
| Disponibilité: | Envoi sous 5 jours ouvrables |
Description du produit » anti-c-erb-2 anticorps
| Antigène | C-erb-2 |
| Immunogène | Synthetic peptide representing the internal domain. |
| Reactivité | Human |
| Clonalité | Monoclonal |
| Format | Supernatant (prediluted) |
| Isotype | IgG1-kappa »Anticorps secondaires correspondants |
| Clone | CB11 |
| Hôte | Mouse |
| Specificité | This antibody reacts with internal domain of c-erbB-2 oncoprotein. c-erbB-2 is a 185 kD transmembrane protein considered to be a growth factor receptor. About 15 to 30% of invasive ductal carcinoma and 70% of in situ ductal carcinoma are positive for c-erbB-2. |
Applications » anti-c-erb-2 anticorps
| Application | Immunohistochemistry (IHC) |
| Indications d'application | Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma. Cellular localization: Cell membrane |
| Concentration | 1 to 4 ug/ml |
| Buffer | This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. |
| Stock | Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label. |
| Domaine de recherche | Récepteurs, Facteurs de croissance |
| Restrictions | For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union |
Références » anti-c-erb-2 anticorps
| Références |
Wright, Angus, Nicholson et al.: "Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer." In: Cancer research
, Vol. 49, Issue 8, pp. 2087-90, 1989 (PubMed)
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Antigènes
