NFKBIA anticorps
Aperçu rapide pour NFKBIA anticorps (ABIN155061)
Antigène
Voir toutes NFKBIA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody detects both phosphorylated and non-phosphorylated forms of IκB-alpha.
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Attributs du produit
- Synonyms: I-kappa-B-alpha, MAD3, NFKBI, I kappa B-alpha, IkappaBalpha, IkB-alpha, NF-kappa-Binhibitor alpha, Major histocompatibility complex enhancer-binding protein MAD3
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Purification
- Immunoaffinity Chromatography.
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Immunogène
- Recombinant Human IkBa
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Isotype
- IgG1
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (N-Term) antibody
NFKBIA Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 74-247) antibodyNFKBIA Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (pSer32), (pSer36) antibodyNFKBIA Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 150-291) antibodyNFKBIA Reactivité: Humain IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 4D4C4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 3-112) antibodyNFKBIA Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-317) antibodyNFKBIA Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 3H4 unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (Center) antibodyNFKBIA Reactivité: Humain, Souris WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibodyNFKBIA Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibodyKD Validated NFKBIA Reactivité: Humain WB, IF (p), FACS Hôte: Lapin Monoclonal 25GB4040 unconjugated Recombinant Antibody
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Indications d'application
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Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, pH 7.2, containing 50 % Glycerol, 1 % BSA and 0.02 % Thimerosal.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
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Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to-70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
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Autre désignation
- NFKBIA / IKBA
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Sujet
- NF-κB is silenced in the cytoplasm by an inhibitory protein, IκB. IκB proteins are phosphorylated by IκB kinase complex consisting of at least three proteins, IKK1/α, IKK2/β, and IKK3/γ. External stimuli such TNF-α or other cytokines results in phosphorylation and degradation of IκB releasing NF-κB dimers. NF-κB dimer subsequently translocates to the nucleus and activates target genes. Six members of IκB family members have been identified. One of the first gene induced following NF-κB activation is IκBα.Synonyms: I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
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ID gène
- 4792
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UniProt
- P25963
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Pathways
- Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
Antigène
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