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Aperçu des produits pour anti-Caspase 4 (CASP4) Anticorps

Full name:
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase Anticorps (CASP4)
Chez sont 264 Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions Caspase 4 Kits (52) et Caspase 4 Protéines (23) et beaucoup plus de produits pour cette protéine. Un total de 352 Caspase 4 produits sont actuellement listés.
CASP1, CASP4, Casp11, CASP13, Caspl, ICE(rel)II, ICEREL-II, ICH-2, ich-3, Mih1/TX, TX
afficher tous les anticorps Gène GeneID UniProt
CASP4 837 P49662
CASP4 12363 P70343
CASP4 114555  

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anti-Human Caspase 4 Anticorps:

anti-Mouse (Murine) Caspase 4 Anticorps:

anti-Rat (Rattus) Caspase 4 Anticorps:

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anti-Caspase 4 Anticorps mieux référencés

  1. Mouse (Murine) Monoclonal Caspase 4 Primary Antibody pour ELISA, ICC - ABIN265762 : Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. dans The Biochemical journal 2012 (PubMed)
    Show all 19 references for ABIN265762

  2. Human Polyclonal Caspase 4 Primary Antibody pour EIA, IF - ABIN499561 : Kamens, Paskind, Hugunin, Talanian, Allen, Banach, Bump, Hackett, Johnston, Li: Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. dans The Journal of biological chemistry 1995 (PubMed)
    Show all 4 references for ABIN499561

  3. Human Polyclonal Caspase 4 Primary Antibody pour EIA, IHC (p) - ABIN499563 : Gracie, Robertson, McInnes: Interleukin-18. dans Journal of leukocyte biology 2003 (PubMed)
    Show all 4 references for ABIN499563

  4. Human Monoclonal Caspase 4 Primary Antibody pour WB - ABIN967534 : Faucheu, Diu, Chan, Blanchet, Miossec, Hervé, Collard-Dutilleul, Gu, Aldape, Lippke: A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. dans The EMBO journal 1995 (PubMed)
    Show all 2 references for ABIN967534

  5. Human Polyclonal Caspase 4 Primary Antibody pour ELISA, WB - ABIN268673 : Munday, Vaillancourt, Ali, Casano, Miller, Molineaux, Yamin, Yu, Nicholson: Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. dans The Journal of biological chemistry 1995 (PubMed)

  6. Mouse (Murine) Polyclonal Caspase 4 Primary Antibody pour WB - ABIN222879 : Huang, Xie, Qiao, Qiu, Huang, Li, Chen, Liu, Wang, Lin, Wang: Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. dans Toxicological sciences : an official journal of the Society of Toxicology 2015 (PubMed)

  7. Human Monoclonal Caspase 4 Primary Antibody pour WB - ABIN223055 : Kim, Zhang, Hitomi, Lee, Mukherjee: Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. dans Human molecular genetics 2006 (PubMed)

Plus d’anticorps contre Caspase 4 partenaires d’interaction

Human Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Specific activation of caspase-3 (Montrer CASP3 Anticorps) and caspase-4 was found in proplatelets. Consistent with previous observations of caspase-4 autoactivation in response to endoplasmic reticulum (ER) stress, several ER stress marker proteins were expressed during proplatelet formation.

  2. apoptosis is induced by rhein traditional Chinese medicine via induction of endoplasmic reticulum stress, caspase-4 and intracellular calcium in primary human hepatic HL-7702 cells

  3. Caspase-4 and caspase-5 (Montrer CASP5 Anticorps) mediate IL-1alpha and IL-1beta (Montrer IL1B Anticorps) release from human monocytes after lipopolysaccharides stimulation.

  4. both caspase-4 and caspase-5 (Montrer CASP5 Anticorps) are functionally important for appropriate responses to intracellular Gram-negative bacteria.

  5. caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 (Montrer NLRP3 Anticorps) inflammasome activation to drive IL-1beta (Montrer IL1B Anticorps) maturation.

  6. This study reveled that CASP4 having a central role in the bipolar disease and schizophrenia manifestation.

  7. NF-kappaB (Montrer NFKB1 Anticorps) can mediate Fas (Montrer FAS Anticorps)-induced apoptosis through caspase-4 protease

  8. implicate caspase-4 as a critical regulator of noncanonical inflammasome activation that initiates defense against bacterial pathogens in primary macrophages

  9. Authors observed increases in the endoplasmic reticulum stress markers BiP (Montrer GDF10 Anticorps) and cleaved caspase-4 in Duchenne muscular dystrophy (Montrer DMD Anticorps) patient biopsies, compared with controls.

  10. The caspase-4/11 inflammasome also governs activation of the proinflammatory cytokine, interleukin (IL)-18 (Montrer IL18 Anticorps), in response to intracellular and extracellular enteric pathogens.

Mouse (Murine) Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Caspase-11 targets cofilin (Montrer CFL1 Anticorps) via the RhoA GTPase, whereas caspase-1 (Montrer CASP1 Anticorps) engages the Slingshot phosphatase

  2. Hyperactive dendritic cells induce potent adaptive immune responses and are elicited by caspase-11, an enzyme that binds oxidized phospholipids and bacterial lipopolysaccharide.

  3. Caspase-1 (Montrer CASP1 Anticorps)-activated IL-18 (Montrer IL18 Anticorps) induces IFN-gamma (Montrer IFNG Anticorps) to prime caspase-11 and rapidly clear Burkholderia thailandensis infection.

  4. These results argue that caspase-1 (Montrer CASP1 Anticorps), -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  5. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  6. But not in Casp11(-/-), Panx1 (Montrer PANX1 Anticorps)(-/-), or P2x7 (Montrer P2RX7 Anticorps)(-/-) mice.

  7. active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3 (Montrer NLRP3 Anticorps).

  8. Data show that caspase-1 (Montrer CASP1 Anticorps) but not caspase-11 was essential for the functional activities of the NLRC4 (Montrer NLRC4 Anticorps) inflammasome.

  9. Data indicate that genetic ablation of caspase-1 (Montrer CASP1 Anticorps) and -11 from cpdm (Montrer SHARPIN Anticorps) mice significantly reduced skin inflammation in sharpin (Montrer SHARPIN Anticorps)-deficient mice.

  10. These results suggest a role for other caspase-11 effector mechanisms such as pyroptosis in protection against intestinal inflammation.

Caspase 4 (CASP4) profil antigène

Antigen Summary

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 4 (CASP4)

  • caspase 4 (CASP4) anticorps
  • caspase 11 (LOC100101589) anticorps
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) anticorps
  • caspase 4, apoptosis-related cysteine peptidase (Casp4) anticorps
  • caspase-4-like (LOC100359184) anticorps
  • CASP1 anticorps
  • CASP4 anticorps
  • Casp11 anticorps
  • CASP13 anticorps
  • Caspl anticorps
  • ICE(rel)II anticorps
  • ICEREL-II anticorps
  • ICH-2 anticorps
  • ich-3 anticorps
  • Mih1/TX anticorps
  • TX anticorps

Protein level used designations for CASP4

caspase 4 , CASP-4 , ICE(rel)-II , apoptotic cysteine protease Mih1/TX , caspase 4, apoptosis-related cysteine protease , caspase-4 , protease ICH-2 , protease TX , CASP-11 , caspase 11, apoptosis-related cysteine peptidase , caspase 11, apoptosis-related cysteine protease , caspase-11 short form splicing , protease ICH-3 , caspase 11 , CASP-1 , ICE , IL-1 beta-converting enzyme , IL-1BC , caspase-1 , caspase-1/caspase-4 hybrid , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , CASP-13 , ERICE , caspase 13 , caspase-13 , evolutionary related interleukin-1-beta-converting enzyme

704864 Macaca mulatta
100101589 Oryctolagus cuniculus
837 Homo sapiens
12363 Mus musculus
114555 Rattus norvegicus
403724 Canis lupus familiaris
338039 Bos taurus
100359184 Oryctolagus cuniculus
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