anti-Souris Caspase 8 anticorps pour Enzyme Immunoassay

Recommended Caspase 8 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Anticorps
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Épitope
C-Term
42
19
18
16
15
12
10
10
9
8
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
360
120
95
25
21
20
3
2
1
Hôte
Lapin
278
115
10
2
Clonalité
Polyclonal
Conjugué
Cet anticorp Caspase 8 est non-conjugé
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
360
109
92
79
51
36
36
27
14
13
9
7
6
5
2
2
2
1
1
1
1
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N° du produit ABIN5554665
$ 375.38
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN5554666 EIA WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN187452 EIA IHC (fro) WB Rat IgG1 Connectez-vous pour afficher 1G12
1 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Connectez-vous pour afficher 1H11

General

Antigène Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Anticorps
Épitope C-Term
(42), (19), (18), (16), (15), (12), (10), (10), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(360), (120), (95), (25), (21), (20), (3), (2), (1)
Hôte Lapin
(278), (115), (10), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp Caspase 8 est non-conjugé
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(360), (109), (92), (79), (51), (36), (36), (27), (14), (13), (9), (7), (6), (5), (2), (2), (2), (1), (1), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-Caspase 8 anticorps

Détail du antigène Caspase 8 Information d'application Stockage Images
Specificité Caspase-8 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-8 isoform A.
Purification Affinity chromatography purified via peptide column
Immunogène Virus Casp-8 / FLICE / MACH / Mch5 (C-Terminus) Peptide
Isotype IgG

Détail du antigène Caspase 8

Détail du produit anti-Caspase 8 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation Caspase-8 (CASP8 Antibody Extrait)
Sujet Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex (4). The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation (reviewed in 5). FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis (6).Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
ID gène 841
NCBI Accession NP_001219
UniProt Q14790
Domaine de recherche Apoptosis/Necrosis
Pathways Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Information d'application

Détail du produit anti-Caspase 8 anticorps Détail du antigène Caspase 8 Stockage Images Haut de la page
Indications d'application ELISA. Western Blot: Caspase-8 antibody can be used for the detection of caspase-8 at 0.5 μg/mL. Depending on cell lines or tissues used, either full-length or other cleavage products maybe observed. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-Caspase 8 anticorps Détail du antigène Caspase 8 Information d'application Images Haut de la page
Buffer PBS containing 0.02 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C.