anti-Boeuf (Vache) KRT18 anticorps pour Immunofluorescence

Recommended KRT18 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Keratin 18 (KRT18) Anticorps
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • CYK18
  • K18
  • CK18
  • Krt1-18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krtt1c6
  • zgc:66015
  • keratin 18
  • similar to Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
  • Keratin, type I cytoskeletal 18
  • cytokeratin 18
  • K18, simple type I keratin
  • zgc:77517
  • krt18
  • KRT18
  • k1c18
  • LOC100008885
  • LOC100136778
  • Krt18
  • zgc:77517
Reactivité
Boeuf (Vache), Chien, Hamster, Humain, Souris, Porc, Rat (Rattus), Mouton, Truite
947
199
170
70
64
41
35
33
27
27
23
20
17
15
12
7
7
5
5
4
3
3
2
1
1
1
1
Hôte
Souris
698
275
12
11
4
3
2
Clonalité
Monoclonal
Conjugué
Cet anticorp KRT18 est conjugé à/à la FITC
52
47
22
18
17
17
14
14
14
14
14
14
14
14
14
11
11
8
4
3
3
3
3
3
3
3
3
2
2
2
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
656
466
388
349
330
300
225
179
125
40
26
18
18
14
11
9
3
2
2
1
1
1
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N° du produit ABIN111182
$ 434.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN3026966 FACS IF IHC (p) WB Mouse IgG1, kappa Connectez-vous pour afficher C-04 or Ks18-04
1 ABIN3026968 FACS IF IHC (p) WB Mouse IgG1, kappa Connectez-vous pour afficher C-04 or Ks18-04

General

Antigène Keratin 18 (KRT18) Anticorps
Reactivité Boeuf (Vache), Chien, Hamster, Humain, Souris, Porc, Rat (Rattus), Mouton, Truite
(947), (199), (170), (70), (64), (41), (35), (33), (27), (27), (23), (20), (17), (15), (12), (7), (7), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Hôte Souris
(698), (275), (12), (11), (4), (3), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp KRT18 est conjugé à/à la FITC
(52), (47), (22), (18), (17), (17), (14), (14), (14), (14), (14), (14), (14), (14), (14), (11), (11), (8), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(656), (466), (388), (349), (330), (300), (225), (179), (125), (40), (26), (18), (18), (14), (11), (9), (3), (2), (2), (1), (1), (1)
Pubmed 9 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-KRT18 anticorps

Détail du antigène KRT18 Information d'application Stockage References for anti-KRT18 antibody (ABIN111182) Images
Specificité Ks 18.04 represents an excellent marker to discriminate simple epithelia from those of different origin. Tumors Specifically Detected: all adenocarcinoma, mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma. Polypeptide Reacting: Mr 45 000 polypeptide (human keratin K18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia. Reacts with HeLa and MCF-7 (cell lines tested so far).
Purification Protein A Chromatography
Immunogène Human keratin K18 from a HeLa cytoskeletal preparation
Clone Ks18-04
Isotype IgG1

Détail du antigène KRT18

Détail du produit anti-KRT18 anticorps Information d'application Stockage References for anti-KRT18 antibody (ABIN111182) Images Haut de la page
Antigène
Autre désignation Cytokeratin 18 (KRT18 Antibody Extrait)
Sujet Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
ID gène 3875
NCBI Accession NP_000215
UniProt P05783
Domaine de recherche Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptose, Caspase Cascade in Apoptosis

Information d'application

Détail du produit anti-KRT18 anticorps Détail du antigène KRT18 Stockage References for anti-KRT18 antibody (ABIN111182) Images Haut de la page
Indications d'application Immunoflourescence. Cytological material. Flow Cytometry: 1/5-1/10. Immunohistochemistry of Frozen Sections. Immunohistochemistry of Paraffin Sections: 1/10. Working dilution: 1/10 for immunohistochemistry. Incubation Time: 1 h at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-KRT18 anticorps Détail du antigène KRT18 Information d'application References for anti-KRT18 antibody (ABIN111182) Images Haut de la page
Format Liquid
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-KRT18 antibody (ABIN111182)

Détail du produit anti-KRT18 anticorps Détail du antigène KRT18 Information d'application Stockage Images Haut de la page
Produit citée dans:

Trowe, Airik, Weiss, Farin, Foik, Bettenhausen, Schuster-Gossler, Taketo, Kispert: "Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter." dans: Development (Cambridge, England), Vol. 139, Issue 17, pp. 3099-108, 2012

Hantel, Lewrick, Schneider, Zwermann, Perren, Reincke, Süss, Beuschlein: "Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency." dans: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 2, pp. 943-52, 2010

Ikenouchi, Matsuda, Furuse, Tsukita: "Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail." dans: Journal of cell science, Vol. 116, Issue Pt 10, pp. 1959-67, 2003

Stumptner, Fuchsbichler, Heid, Zatloukal, Denk: "Mallory body--a disease-associated type of sequestosome." dans: Hepatology (Baltimore, Md.), Vol. 35, Issue 5, pp. 1053-62, 2002

Bantel, Ruck, Gregor, Schulze-Osthoff: "Detection of elevated caspase activation and early apoptosis in liver diseases." dans: European journal of cell biology, Vol. 80, Issue 3, pp. 230-9, 2001

Gomi, Yokoyama, Fujimoto, Ikeda, Katoh, Itoh, Itohara: "Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions." dans: Neuron, Vol. 14, Issue 1, pp. 29-41, 1995

Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." dans: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." dans: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989

Moll, Franke, Schiller, Geiger, Krepler: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." dans: Cell, Vol. 31, Issue 1, pp. 11-24, 1983