Aperçu des produits pour anti-PARP1 (PARP1) Anticorps

Full name:
anti-Poly (ADP-Ribose) Polymerase 1 Anticorps (PARP1)
Chez www.anticorps-enligne.fr sont 424 Poly (ADP-Ribose) Polymerase 1 (PARP1) Anticorps de 27 de différents fournisseurs disponibles. De plus, nous expédions PARP1 Kits (39) et PARP1 Protéines (31) et beaucoup plus de produits pour cette protéine. Un total de 522 PARP1 produits sont actuellement listés.
Synonymes:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1
afficher tous les anticorps Gène GeneID UniProt
PARP1 142 P09874
PARP1 25591 P27008
PARP1 11545  

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anti-PARP1 Anticorps mieux référencés

  1. Human Polyclonal PARP1 Primary Antibody pour IP, IHC - ABIN2854261 : Lamarre, Talbot, de Murcia, Laplante, Leduc, Mazen, Poirier: Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study. dans Biochimica et biophysica acta 1988 (PubMed)
    Show all 8 references for 2854261

  2. Human Polyclonal PARP1 Primary Antibody pour ChIP, WB - ABIN2668274 : Kim, Mauro, Gévry, Lis, Kraus: NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. dans Cell 2004 (PubMed)
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  3. Human Monoclonal PARP1 Primary Antibody pour IF, WB - ABIN394297 : Lee, Bang, Park, Kim, Shin, Bae: Lack of association between poly(ADP-ribose) polymerase (PARP) polymorphisms and rheumatoid arthritis in a Korean population. dans Rheumatology international 2012 (PubMed)
    Show all 5 references for 394297

  4. Human Polyclonal PARP1 Primary Antibody pour WB - ABIN1881628 : Dong, Bey, Li, Kabbani, Yan, Xie, Hsieh, Gao, Boothman: Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation. dans Cancer research 2010 (PubMed)
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  5. Human Polyclonal PARP1 Primary Antibody pour WB - ABIN1881627 : Krishnakumar, Kraus: PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. dans Molecular cell 2010 (PubMed)
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  6. Human Polyclonal PARP1 Primary Antibody pour IF (p), IHC (p) - ABIN677903 : Ma, Liu, Wang, Liu, Chen, Valle, Zuo, Xia, Liu: Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. dans ACS nano 2015 (PubMed)
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  7. Human Polyclonal PARP1 Primary Antibody pour EIA, WB - ABIN358977 : Tao, Gao, Hoffman, Liu: Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif. dans Biochemistry 2008 (PubMed)
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  8. Cow (Bovine) Polyclonal PARP1 Primary Antibody pour WB - ABIN2778108 : Pétrilli, Herceg, Hassa, Patel, Di Paola, Cortes, Dugo, Filipe, Thiemermann, Hottiger, Cuzzocrea, Wang: Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. dans The Journal of clinical investigation 2004 (PubMed)

Plus d’anticorps contre PARP1 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The results demonstrate that PARylation process in Drosophila is tightly regulated in the context of strands-breaks repair; PARP is essential during the maintenance of DNA integrity, but dispensable in the DNA repair process.

  2. A mutation of Parp also increases NAD+ levels; although, this was only observed in parkin (Montrer PARK2 Anticorps) mutant flies and not in the heterozygous Parp mutants, possibly owing to an increased PARP activity in the parkin (Montrer PARK2 Anticorps) mutants.

  3. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (Montrer H2AFV Anticorps) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  4. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  5. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  6. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  7. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  8. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  9. PARP-e autoregulates Parp transcription

  10. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The NF90 (Montrer MMP4 Anticorps) regulates PARP1 mRNA stability in hepatocellular carcinoma cells, and NF90 (Montrer MMP4 Anticorps) is a potential target to inhibit PARP1 activity.

  2. In response to UV irradiation, DICER (Montrer DICER1 Anticorps) is recruited to chromatin in a ZRF1 (Montrer DNAJC2 Anticorps)-mediated manner. The H2A-ubiquitin binding protein ZRF1 (Montrer DNAJC2 Anticorps) and DICER (Montrer DICER1 Anticorps) together impact on the chromatin conformation via PARP1.

  3. This paper summarises the most significant current literature on the involvement of PARP-1 in gastrointestinal cancer, focusing in particular on its role in the development and occurrence of tumours, providing information about clinical trials and exploring therapeutic possibilities. [review]

  4. PARP-1 stabilizes Sox2 (Montrer SOX2 Anticorps) binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 (Montrer SOX2 Anticorps) pioneer activity at intractable genomic loci.

  5. PARP1 can modulate the tumor-suppressing function of HIPK2 (Montrer HIPK2 Anticorps) by regulating the protein stability of HIPK2 (Montrer HIPK2 Anticorps).

  6. HBx increased signs of DNA damage such as accumulation of 8-hydroxy-2'-deoxyguanosine and comet formation, which were reversed by overexpression of PARP1 and/or Sirt6 (Montrer SIRT6 Anticorps)..physical interaction of HBx and PARP1 accelerates DNA damage by inhibiting recruitment of the DNA repair complex to the damaged DNA sites, which may lead to the onset of hepatocarcinogenesis

  7. these findings provide a foundation for the potential use of PARP1 inhibitors as a new treatment option for lung adenocarcinoma patients with elevated PARP1 expression.

  8. Elevated PARP (Montrer COL11A2 Anticorps) expression correlated with worse prognosis in early stage breast cancer. [meta-analysis]

  9. study demonstrates that the individual and combined expression patterns of the DDR (Montrer DDR1 Anticorps) molecules PARP1, gammaH2AX (Montrer H2AFX Anticorps), BRCA1, and BRCA2 (Montrer BRCA2 Anticorps) could be predictive of the prognosis of STS (Montrer STS Anticorps) patients and suggests that controlling the activity of these DDR (Montrer DDR1 Anticorps) molecules could be employed in new therapeutic stratagems for the treatment of STS (Montrer STS Anticorps)

  10. PARP1/2 inhibitor simmiparib causes growth inhibition in cancer cell- or tissue-derived xenografts in nude mice.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. no difference was found in the level of SBDP145 between muscles, while SBDP120 and PARP-1 cleavage products were not detected

  2. ADPRT Val762Ala and APE1 (Montrer APEX1 Anticorps) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  3. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  4. FGF2 (Montrer FGF2 Anticorps) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (Montrer MAPK1 Anticorps))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The findings suggest that PARP1 inhibition protects against long-term ethanol-induced liver injury, as indicated by limited hepatocytes steatosis, apoptosis, inflammation levels, and neutrophil infiltration, mainly by limiting KC activation during the initiation of ALD.

  2. PARP-1 knockout resulted in lowered arginase II (Montrer ARG2 Anticorps) expression in macrophages and aortic endothelial cells.

  3. PARP-1 stabilizes Sox2 (Montrer SOX2 Anticorps) binding to nucleosomes at suboptimal sites through cooperative interactions on DNA to regulate Sox2 (Montrer SOX2 Anticorps) pioneer activity at intractable genomic loci.

  4. Delayed healing in ischemic and diabetic wounds is caused by PARP hyperactivity, and PARP inhibition significantly enhanced ischemic and diabetic wound healing by promoting angiogenesis.

  5. The findings highlight specific non-overlapping functions of PARP1 and PARP2 (Montrer PARP2 Anticorps) at H2AX (Montrer H2AFX Anticorps)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 in nonhomologous end-joining-deficient cells.

  6. data establish the importance of XRCC1 (Montrer XRCC1 Anticorps) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  7. this study shows that PARP-1 inhibition plays role in puerarin-mediated protection from liver fibrosis

  8. might be involved in streptomycin ototoxicity by regulating AIF (Montrer AIFM1 Anticorps) translocation in cochlear hair cells

  9. Nonionizing radiofrequency exposure is capable of inducing PARP-1.

  10. our data suggest that Parp1 is involved in the plastic remodeling of chromatin structure after NT by supporting DNA repair and specific histone code modifications.

PARP1 profil antigène

Antigen Summary

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) anticorps
  • poly (ADP-ribose) polymerase 1 (PARP1) anticorps
  • poly (ADP-ribose) polymerase 1 (Parp1) anticorps
  • poly (ADP-ribose) polymerase 1 (parp1) anticorps
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) anticorps
  • poly ADP-ribose polymerase (Parp) anticorps
  • 5830444G22Rik anticorps
  • Adprp anticorps
  • Adprt anticorps
  • ADPRT 1 anticorps
  • Adprt1 anticorps
  • AI893648 anticorps
  • ARTD1 anticorps
  • BEST:LD21673 anticorps
  • C80510 anticorps
  • CG17685 anticorps
  • CG17696 anticorps
  • CG17718 anticorps
  • CG40411 anticorps
  • D.PARP anticorps
  • Dm.pARTa anticorps
  • Dmel\\CG40411 anticorps
  • dPARP anticorps
  • LD21673.3prime anticorps
  • padprt-1 anticorps
  • parp anticorps
  • parp-1 anticorps
  • PARP1 anticorps
  • ppol anticorps
  • sPARP-1 anticorps

Protein level used designations for PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPECIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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