Aperçu des produits pour anti-XIAP (XIAP) Anticorps

Full name:
anti-X-Linked Inhibitor of Apoptosis Anticorps (XIAP)
Chez www.anticorps-enligne.fr sont 185 X-Linked Inhibitor of Apoptosis (XIAP) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions XIAP Kits (19) et XIAP Protéines (15) et beaucoup plus de produits pour cette protéine. Un total de 234 XIAP produits sont actuellement listés.
Synonymes:
1110015C02Rik, Aipa, Api3, Birc4, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, MIHA, mXIAP, riap3, XLP2, xxiap

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anti-Human XIAP Anticorps:

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anti-XIAP Anticorps mieux référencés

  1. Dog (Canine) Monoclonal XIAP Primary Antibody pour IF, IP - ABIN968132 : Duckett, Nava, Gedrich, Clem, Van Dongen, Gilfillan, Shiels, Hardwick, Thompson: A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. dans The EMBO journal 1996 (PubMed)
    Show all 6 references for 968132

  2. Frog Monoclonal XIAP Primary Antibody pour IF, IP - ABIN968163 : Deng, Lin, Wu: TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. dans Genes & development 2002 (PubMed)
    Show all 5 references for 968163

  3. Human Polyclonal XIAP Primary Antibody pour IF (cc), IF (p) - ABIN674364 : Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. dans PLoS ONE 2013 (PubMed)
    Show all 4 references for 674364

  4. Human Polyclonal XIAP Primary Antibody pour IHC (p), WB - ABIN3044425 : Li, Zhang, Fang, Yan, Zhao, Feng, Ma, Ye: Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1. dans Biochemical and biophysical research communications 2013 (PubMed)
    Show all 3 references for 3044425

  5. Human Polyclonal XIAP Primary Antibody pour EIA, IHC (p) - ABIN358604 : Srinivasula, Gupta, Datta, Zhang, Hegde, Cheong, Fernandes-Alnemri, Alnemri: Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 358604

  6. Human Polyclonal XIAP Primary Antibody pour IHC (p), WB - ABIN390070 : Miranda, Dyer, Grandis, Johnson: Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells. dans Leukemia 2003 (PubMed)
    Show all 2 references for 390070

Plus d’anticorps contre XIAP partenaires d’interaction

Human X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. The authors find that primary human aggressive B-cell lymphoma samples exhibit high USP9X (Montrer USP9X Anticorps) expression that correlate with XIAP overexpression.

  2. Findings reveal important new insights into how XIAP 3'UTR (Montrer UTS2R Anticorps) works, suggesting that the non-coding XIAP 3'UTR (Montrer UTS2R Anticorps) serves as a competitor for miRNA binding and subsequently inactivates miRNA functions, by which XIAP 3'UTR (Montrer UTS2R Anticorps) frees the target mRNAs from being repressed.

  3. XIAP is stable during mitotic arrest, but its function is controlled through phosphorylation by the mitotic kinase CDK1 (Montrer CDK1 Anticorps)-cyclin-B1 (Montrer CCNB1 Anticorps) at S40.

  4. our findings suggest that X-linked inhibitor of apoptosis protein 3'-untranslated region serves as a competitive endogenous RNA for HMGA2 to activate hepatocellular carcinoma progression by arresting endogenous let-7a-5p.

  5. In chronic myeloid leukemia (Montrer BCL11A Anticorps) cells, EZH2 (Montrer EZH2 Anticorps) modulates epigenetic changes at DNA methylated regions encoding miR (Montrer MLXIP Anticorps)-219 and downregulates the level of miR (Montrer MLXIP Anticorps)-219. Downregulation of miR (Montrer MLXIP Anticorps)-219 results in upregulation of XIAP and supports the survival of leukemia cells.

  6. IFNgamma positively affects NOD2 (Montrer NOD2 Anticorps)-mediated signaling in human conventional dendritic cells, in a manner considerably dependent on XIAP and partially dependent on mTOR (Montrer FRAP1 Anticorps).

  7. miR (Montrer MLXIP Anticorps)-137 expression is inversely correlated with the level of XIAP protein in both ovarian cancer tissues and cell lines. these data suggest that multiple miRNAs can regulate XIAP via its 3'UTR (Montrer UTS2R Anticorps). miR (Montrer MLXIP Anticorps)-137 can sensitise ovarian cancer cells to cisplatin-induced apoptosis, providing new insight into overcoming drug resistance in ovarian cancer

  8. results of this work support the role of XIAP in mediating NOD2 (Montrer NOD2 Anticorps) signaling while reconciling the role of X-linked lymphoproliferative syndrome 2 and very-early-onset inflammatory bowel disease XIAP mutations in inflammatory cell death and provide a set of tools and framework to rapidly test newly discovered XIAP variants.

  9. Using recombinant proteins, this study investigated the influence of survivin (Montrer BIRC5 Anticorps) on the inhibition of caspase-9 (Montrer CASP9 Anticorps) by XIAP in vitro. With a fluorescence-based assay for the apoptosome-stimulated activity of caspase-9 (Montrer CASP9 Anticorps), the study shows that survivin (Montrer BIRC5 Anticorps) has no effect on the inhibition of caspase-9 (Montrer CASP9 Anticorps) by XIAP, neither in the presence nor in the absence of Smac (Montrer DIABLO Anticorps).

  10. Study found a negative correlation between Smac (Montrer DIABLO Anticorps) and XIAP at the level of protein but not mRNA in non-small cell lung carcinoma (NSCLC) patients. Overexpressed XIAP could degrade through ubiquitination, the mature Smac (Montrer DIABLO Anticorps) inhibiting NSCLC apoptosis.

Mouse (Murine) X-Linked Inhibitor of Apoptosis (XIAP) interaction partners

  1. These results indicate that XIAP plays an important physiologic role in regulating sublethal CASP-3 (Montrer CASP3 Anticorps) activity within central neurons and thereby facilitates synaptic plasticity and memory acquisition.

  2. XIAP antagonizes the switch from TNFalpha (Montrer TNF Anticorps)-induced apoptosis to necroptosis in mouse neutrophils.

  3. Results show that XIAP binds to the C terminus of Ptch1 (Montrer PTCH1 Anticorps) and mediates the death-dependent function of Ptch1 (Montrer PTCH1 Anticorps).

  4. XIAP modulates ubiquitylation of RIP1 (Montrer RALBP1 Anticorps) and suppresses RIP3 (Montrer MPRIP Anticorps)-dependent cell death and inflammasome activation in response to TNF (Montrer TNF Anticorps)-signaling in innate immune cells.

  5. XIAP deficiency selectively impaired B-cell chronic lymphocytic leukemia/lymphoma 10 (BCL10 (Montrer BCL10 Anticorps))-mediated innate responses to dectin-1 (Montrer CLEC7A Anticorps) ligands but did not affect responses to various Toll (Montrer TLR4 Anticorps)-like receptor agonists.

  6. XIAP mRNA level was also reduced in the BRE (Montrer BRE Anticorps)-depleted cells, but the level of reduction was less profound than that of the protein level. However, BRE (Montrer BRE Anticorps) could not delay protein turnover of XIAP.

  7. Identify xIAP and cIAP1 (Montrer BIRC2 Anticorps) as molecular targets of ceramide and show ceramide analog LCL85 is an effective sensitizer in overcoming resistance of metastatic colon and breast cancers to apoptosis induction to suppress metastasis in vivo.

  8. XIAP-/- DRG sensory neurons degenerate more rapidly and contain more active caspase-3 (Montrer CASP3 Anticorps).

  9. XIAP ubiquitylates RIPK2 (Montrer RIPK2 Anticorps) and recruits the linear ubiquitin chain assembly complex to NOD2 (Montrer NOD2 Anticorps)

  10. XIAP is expressed in oligodendrocytes in vivo and in vitro. Increased XIAP expression is associated with protection against selected cell death pathways, whereas decreased expression increases oligodendroglial cell death.

XIAP profil antigène

Antigen Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

Alternative names and synonyms associated with XIAP

  • X-linked inhibitor of apoptosis (XIAP) anticorps
  • X-linked inhibitor of apoptosis (xiap) anticorps
  • X-linked inhibitor of apoptosis (Xiap) anticorps
  • 1110015C02Rik anticorps
  • Aipa anticorps
  • Api3 anticorps
  • Birc4 anticorps
  • hIAP-3 anticorps
  • hIAP3 anticorps
  • IAP-3 anticorps
  • IAP3 anticorps
  • ILP-1 anticorps
  • ILP1 anticorps
  • MIHA anticorps
  • mXIAP anticorps
  • riap3 anticorps
  • XLP2 anticorps
  • xxiap anticorps

Protein level used designations for XIAP

X-linked inhibitor of apoptosis protein , baculoviral IAP repeat-containing 4 , baculoviral IAP-repeat containing protein 4 , Baculoviral IAP repeat-containing protein 4 , E3 ubiquitin-protein ligase XIAP , X-linked IAP , IAP-like protein , baculoviral IAP repeat-containing protein 4 , inhibitor of apoptosis protein 3 , IAP homolog A , IAP-3 , apoptosis inhibitor 3 , mIAP-3 , mIAP3 , RIAP-3 , apoptosis inhibitor protein 3

GENE ID SPECIES
442989 Canis lupus familiaris
594971 Xenopus (Silurana) tropicalis
331 Homo sapiens
11798 Mus musculus
63879 Rattus norvegicus
733235 Xenopus laevis
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