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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, ICC - ABIN250638
Sarkar, Krishna, Imarisio, Saiki, OKane, Rubinsztein: A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. dans Human molecular genetics 2008
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Cow (Bovine) Polyclonal MAP1LC3B Primary Antibody pour EM, FACS - ABIN153145
Pyo, Nah, Kim, Lee, Heo, Lee, Jung: Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. dans Autophagy 2008
Show all 172 Pubmed References
Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, IHC (fro) - ABIN250640
Mizushima, Yamamoto, Hatano, Kobayashi, Kabeya, Suzuki, Tokuhisa, Ohsumi, Yoshimori: Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. dans The Journal of cell biology 2001
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Human Polyclonal MAP1LC3B Primary Antibody pour ICC, IF - ABIN388484
English, Chemali, Duron, Rondeau, Laplante, Gingras, Alexander, Leib, Norbury, Lippé, Desjardins: Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. dans Nature immunology 2009
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Polyclonal MAP1LC3B Primary Antibody pour IHC (fro), WB - ABIN540679
Miller, Zhao, Stephenson, Cadwell, Pua, Lee, Mizushima, Iwasaki, He, Swat, Virgin: The autophagy gene ATG5 plays an essential role in B lymphocyte development. dans Autophagy 2008
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Cow (Bovine) Polyclonal MAP1LC3B Primary Antibody pour ICC, IF - ABIN269556
Aoki, Takada, Kondo, Sawaya, Aggarwal, Kondo: Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. dans Molecular pharmacology 2007
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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, ICC - ABIN250639
Settembre, Fraldi, Jahreiss, Spampanato, Venturi, Medina, de Pablo, Tacchetti, Rubinsztein, Ballabio: A block of autophagy in lysosomal storage disorders. dans Human molecular genetics 2007
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Human Polyclonal MAP1LC3B Primary Antibody pour WB - ABIN1883178
Han, Hou, Goldstein, Lu, Stolz, Yin, Rabinowich: Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. dans The Journal of biological chemistry 2008
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Human Monoclonal MAP1LC3B Primary Antibody pour FACS, ELISA - ABIN969267
Othman, Kaur, Mutee, Muhammad, Tan: Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues. dans Journal of clinical laboratory analysis 2009
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analysis of the RavZ and LC3 (Montrer MAP1LC3A Anticorps) complex reveals the mechanism for deconjugation of LC3 (Montrer MAP1LC3A Anticorps) on the phagophore membrane
SQSTM1 is ubiquitinated by NEDD4 while LC3 functions as an activator of NEDD4 ligase activity.
Cardiolipin interaction with various Atg8 (Montrer GABARAPL2 Anticorps) human orthologs, namely LC3B, GABARAPL2 (Montrer GABARAPL2 Anticorps) and GABARAP (Montrer GABARAP Anticorps), was investigated.
Insights into links between autophagy and the ubiquitin system showed that LC3B-binding can steer intrinsic NEDD4 E3 ligase activity.
Determined is the three-dimensional crystal structures of LC3B in complex with three different LIR (Montrer CD300C Anticorps) motifs of RavZ from Legionella pneumophila, an intracellular pathogen that can manipulate the host autophagy system.
We found that 25-epi (Montrer TFPI Anticorps) Ritterostatin GN1N induced cell death in melanoma cells at nanomolar concentrations, and this cell death was characterized by inhibition of GRP78 (Montrer HSPA5 Anticorps) expression, increased expression of the ER stress marker CHOP (Montrer DDIT3 Anticorps), loss of mitochondrial membrane potential, and lipidation of the autophagy marker protein LC3B.
Double IF showed the co-localization of AQP5 (Montrer AQP5 Anticorps) and LC3B on BafA1-treated heated cells. In conclusion, we demonstrated that heat shock decreased AQP5 (Montrer AQP5 Anticorps) on cellular membranes and in the cytoplasm by activating autophagic degradation, and heat shock and AQP5 (Montrer AQP5 Anticorps) knockdown exerted similar anticancer effects, suggesting that heat shock exerts anticancer effects via the autophagic degradation of AQP5 (Montrer AQP5 Anticorps).
structural and biochemical results reveal a working model for the specific recognition of FUNDC1 (Montrer FUNDC1 Anticorps) by LC3B and imply that the reversible phosphorylation modification of mitophagy receptors may be a switch for selective mitophagy.
Low expression of MAP1LC3B is associated with lymph node metastasis in gastric cancer.
Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation
The crystal structure of mouse LC3B in complex with the FYCO1 (Montrer FYCO1 Anticorps) LC3 (Montrer MAP1LC3A Anticorps)-interacting region (LIR (Montrer CD300C Anticorps)) reveals the importance of the flanking region of the LIR (Montrer CD300C Anticorps) motif.
Data suggest that maternal nutrition modulates expression of autophagy proteins p62/Sqstm1 (Montrer SQSTM1 Anticorps) and Lc3 (Montrer MAP1LC3A Anticorps)-II/Map1lc3 in liver and hypothalamus of offspring (newborn, suckling, and adult stages); for example, high-fat diet leading to maternal obesity up-regulates p62 (Montrer GTF2H1 Anticorps) and down-regulates Lc3 (Montrer MAP1LC3A Anticorps)-II in neonatal liver. (p62/Sqstm1 (Montrer SQSTM1 Anticorps) = sequestosome 1 (Montrer SQSTM1 Anticorps); Lc3 (Montrer MAP1LC3A Anticorps)-II/Map1lc3 = microtubule-associated protein (Montrer SPAG5 Anticorps) 1-light chain 3)
Treatment of aged mice and their derived macrophages with methyltransferase inhibitor (2)-epigallocatechin-3-gallate (EGCG) or specific DNA methyltransferase 2 (DNMT2 (Montrer TRDMT1 Anticorps)) siRNA restored the expression of Atg5 (Montrer ATG5 Anticorps) and LC3 (Montrer MAP1LC3A Anticorps) in vivo and in vitro.
MREG (Montrer MREG Anticorps)-dependent processing links both autophagic and phagocytic processes in LC3 (Montrer MAP1LC3A Anticorps)-associated phagocytosis. MREG (Montrer MREG Anticorps) participates in coordinating the association of phagosomes with LC3 (Montrer MAP1LC3A Anticorps) for content degradation with the MREG (Montrer MREG Anticorps) loss leading to phagosome accumulation.
This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.
Deficiency of autophagy protein Map1 (Montrer MOAP1 Anticorps)-LC3b mediates IL-17 (Montrer IL17A Anticorps)-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1 (Montrer IL1A Anticorps).
This study suggests that autophagy could play a role in placental invasion system and that nutrient starvation affects LC3B expression.
Data indicate that the recombinant plasmid encoding pCMV-LC3 (Montrer MAP1LC3A Anticorps)-LpqH could be a practical strategy for the development of improved vaccines against Mycobacterium tuberculosis.
Lipidation of the LC3 (Montrer MAP1LC3A Anticorps)/GABARAP (Montrer GABARAP Anticorps) family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3 (Montrer ATG3 Anticorps).
p62 (Montrer GTF2H1 Anticorps)/LC3b complex regulates lung alveolar epithelial cell homeostasis and cytoprotection after hyperoxia.
Data indicate that the expression of MAP1LC3A (Montrer MAP1LC3A Anticorps), B and autophagy-associated genes (ATG5 (Montrer ATG5 Anticorps), mTOR (Montrer FRAP1 Anticorps), Beclin-1 (Montrer BECN1 Anticorps)) was increased in normal pigs, while decreased in miniature pigs.
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1 light chain 3-like protein 2
, MAP1A/MAP1B LC3 B
, MAP1A/MAP1B light chain 3 B
, autophagy-related ubiquitin-like modifier LC3 B
, microtubule-associated proteins 1A/1B light chain 3B
, MAP1A/1B light chain 3 B
, autophagy-related protein LC3 B
, microtubule-associated proteins 1A/1B light chain 3
, microtubule-associated protein 1 light chain 3 beta