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anti-Human Thrombospondin 1 Anticorps:
anti-Rat (Rattus) Thrombospondin 1 Anticorps:
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Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody pour BP, ICC - ABIN151527
Cupi, Sarra, De Nitto, Franzè, Marafini, Monteleone, Del Vecchio Blanco, Paoluzi, Di Fusco, Gentileschi, Ortenzi, Colantoni, Pallone, Monteleone: Defective expression of scavenger receptors in celiac disease mucosa. dans PLoS ONE 2014
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Human Polyclonal Thrombospondin 1 Primary Antibody pour ELISA, WB - ABIN4359279
Pan, Chang, Chuang, Hung: The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. dans Experimental biology and medicine (Maywood, N.J.) 2008
Genetic variants of THBS1 were significantly more frequent in patients affected by idiopathic/genetic generalized epilepsies than in non-epileptic controls.
In pulmonary hypertension TSP1-CD47 (Montrer CD47 Anticorps) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
High THBS1 expression is associated with primary effusion lymphoma.
Results show that the presence of OPN (Montrer SPP1 Anticorps) and TSP-1 in the serum of patients with non-small cell lung cancer may reflect the aggressiveness of the tumor.
KLK4 (Montrer KLK4 Anticorps) further liberated an N-terminal product, with purported angiogenic activity, from thrombospondin-1 (TSP1) and cleaved TSP1 in an osteoblast-derived matrix.
Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1/CD47 (Montrer CD47 Anticorps) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
The levels of CD36 (Montrer CD36 Anticorps), STAT3 (Montrer STAT3 Anticorps) and TGFbetaR2 mRNA were significantly higher in the TSP1-high group.
Study discovered novel and independent associations of prediabetes and related traits with MASP1 (Montrer MASP1 Anticorps), and some evidence for associations with THBS1, GPLD1 (Montrer GPLD1 Anticorps) and ApoA-IV (Montrer APOA4 Anticorps), suggesting a role for these proteins in the pathophysiology of type 2 diabetes.
TSP-1 deficiency promotes maladaptive remodelling of the ECM (Montrer MMRN1 Anticorps) leading to accelerated abdominal aortic aneurysms progression.
In pulmonary hypertension TSP1 (Montrer GZMA Anticorps)-CD47 (Montrer CD47 Anticorps) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
HIF-1alpha (Montrer HIF1A Anticorps) induced angiogenesis by upregulating not only vascular endothelial growth factor but also miR (Montrer MLXIP Anticorps)-21 via inhibiting a novel target gene TSP-1 (Montrer GZMA Anticorps). Both of them may contribute to the protective effect of HIF-1alpha (Montrer HIF1A Anticorps) on renal I/R injury.
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (Montrer GZMA Anticorps)/CD47 (Montrer CD47 Anticorps) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
TSP-1 (Montrer GZMA Anticorps) deficiency promotes maladaptive remodelling of the ECM (Montrer MMRN1 Anticorps) leading to accelerated abdominal aortic aneurysms progression.
TSP-1 (Montrer GZMA Anticorps) suppressed insulin (Montrer INS Anticorps) signaling in cultured muscle cells, which was accompanied by the activation of stress signaling such as JNK (Montrer MAPK8 Anticorps), p38 (Montrer CRK Anticorps), and IKK (Montrer CHUK Anticorps).
Three transcription factors were overexpressed and eleven underexpressed in TSP1 (Montrer GZMA Anticorps)(-/-) compared to WT LGs (Montrer LGSN Anticorps).
THSD1 (Montrer THSD1 Anticorps) is a new regulator of endothelial barrier function during vascular development and protects intraplaque microvessels against haemorrhaging in advanced atherosclerotic lesions
Data indicate that thrombospondin-1 may contribute to a destructive macrophage response in dysferlinopathy and pose the intriguing possibility that thrombospondin-1 levels may serve as a biomarker for disease progression.
demonstrate that HIF-2alpha (Montrer EPAS1 Anticorps) is clearly implicated in the TSP1 (Montrer GZMA Anticorps) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction
Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (Montrer TP53 Anticorps) expression or mutational status
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (Montrer THBS2 Anticorps) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (Montrer THBS2 Anticorps), up-regulates expression of FGF2 (fibroblast growth factor 2 (Montrer FGF2 Anticorps)).
Thrombospondin has a role in inducing RhoA (Montrer RHOA Anticorps) inactivation through FAK (Montrer PTK2 Anticorps)-dependent signaling to stimulate focal adhesion disassembly
Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.
Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (Montrer INS Anticorps)-like growth factor
The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications
The novel finding that TSP-1-induced migration is dependent on the CD44 (Montrer CD44 Anticorps) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (Montrer KDM5D Anticorps)).
These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (Montrer IGF1 Anticorps) and the mechanisms by which hyperglycemia regulates TSP-1 protein.
Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (Montrer TGFB1 Anticorps) expression.
ELL (Montrer ELL Anticorps) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation
May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
, thrombospondin type-1 domain-containing protein 1
, thrombospondin, type I, domain 1
, transmembrane molecule with thrombospondin module
, cancer/testis antigen 36
, glyceraldehyde-3-phosphate dehydrogenase-like 5
, testis specific protein 1 (probe H4-1 p3-1)
, testis-specific protein TPX-1
, thrombospondin 1