Aperçu des produits pour anti-PKD2 (PKD2) Anticorps

Full name:
anti-Protein Kinase D2 Anticorps (PKD2)
Chez www.anticorps-enligne.fr sont 124 Protein Kinase D2 (PKD2) Anticorps de 14 de différents fournisseurs disponibles. De plus, nous expédions PKD2 Protéines (13) et PKD2 Kits (8) et beaucoup plus de produits pour cette protéine. Un total de 153 PKD2 produits sont actuellement listés.
Synonymes:
AI325941, APKD2, nPKC-D2, Pc-2, PC2, PKD2, PKD4, PRKD2, RGD1308054, TRPP2

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anti-Human PKD2 Anticorps:

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anti-PKD2 Anticorps mieux référencés

  1. Human Polyclonal PKD2 Primary Antibody pour IP, WB - ABIN152061 : Liu, Evans, Britton, Zachary: The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis. dans Oncogene 2008 (PubMed)
    Show all 8 references for 152061

  2. Human Polyclonal PKD2 Primary Antibody pour EIA, IHC (p) - ABIN360330 : Stayner, Zhou: Polycystin channels and kidney disease. dans Trends in pharmacological sciences 2001 (PubMed)
    Show all 5 references for 360330

Plus d’anticorps contre PKD2 partenaires d’interaction

Human Protein Kinase D2 (PKD2) interaction partners

  1. Annualized median liver growth rates were 1.68, 1.5 and 1.24% for PKD1 (Montrer PKD1 Anticorps)-T, PKD1 (Montrer PKD1 Anticorps)-NT and PKD2 mutations, respectively (P = 0.49), and remained unaffected by the ADPKD genotype when adjusted for age, gender and baseline HtLV.

  2. Here, we review previous studies that connect the molecular properties of the domains of PC2 (Montrer KRT6B Anticorps) Cterm to distinct aspects of PC2 (Montrer KRT6B Anticorps) functions and regulation.

  3. Data show that in 82 (87.2%) of the patients, pathogenic mutations were detected in PKD1 (Montrer PKD1 Anticorps) (79.0%-92.5%), whereas in 12 (12.8%) patients pathogenic mutations were detected in PKD2 (7.5%-21.0%).

  4. Two cryo-EM structures of distinct channel states of full-length human PC2 (Montrer KRT6B Anticorps) in complex with lipids and cations.

  5. The structure of human PC2 (Montrer KRT6B Anticorps) in a closed conformation, solved by electron cryomicroscopy at 4.2-A resolution.

  6. SNPs in and near PKD2 showed significant evidence of association in individual samples of black adults (rs17013735, P-value=0.0009) and white adults (rs11938025; P-value=0.0005; rs2725270, P-value=0.003).

  7. Pancreatic cysts were more prevalent in patients with ADPKD with PKD2 mutation than in control subjects or patients with PKD1 (Montrer PKD1 Anticorps) mutation.

  8. This study discovered and characterized a novel, highly conserved N-terminal domain, comprising 92 amino acids, which mediates dimerization of Protein Kinase D (PKD) isoforms, PKD1 (Montrer PKD1 Anticorps), PKD2, and PKD3 (Montrer PRKD3 Anticorps) monomers.

  9. This suggests that a precise dosage of PC2 (Montrer KRT6B Anticorps) is necessary for an adequate mechanosensitive alpha-actinin (Montrer ACTN1 Anticorps) recruitment at junctions.

  10. PKD1 (Montrer PKD1 Anticorps) and PKD2 are susceptibility genes for familial intracranial aneurysms in a Japanese population.

Mouse (Murine) Protein Kinase D2 (PKD2) interaction partners

  1. Our studies demonstrate that PKD1 (Montrer PKD1 Anticorps)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (Montrer DGKA Anticorps) effect on MVB secretory traffic.

  2. Results reveal that whereas protein kinase D1 (Montrer PRKD1 Anticorps) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  3. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (Montrer CD8A Anticorps)(+) T cells that became effector cells.

  4. Protein kinase D2 promotes in vitro osteoclast differentiation and fusion

  5. A bioinformatic screen identified the serine-threonine kinase (Montrer CDK4 Anticorps) protein kinase D2 (PRKD2) as a potential effector of GABP in hematopoietic stem cells

  6. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by alpha/beta mature TCR complexes in peripheral T-cells.

  7. PKD2 is a common signaling target downstream of various agonist receptors in platelets and G(q)-mediated signals along with calcium and novel PKC (Montrer PKC Anticorps) isoforms, in particular, PKCdelta (Montrer PKCd Anticorps) activate PKD2 in platelets.

  8. Data demonstrate that, unlike PKD1 (Montrer PKD1 Anticorps), PKD2 catalytic activity is dispensable for normal embryogenesis.

  9. PKD2, like PKD (Montrer PRKD1 Anticorps), facilitates mitogenesis in 3T3 cells

PKD2 profil antigène

Antigen Summary

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PKD2

  • protein kinase D2 (PRKD2) anticorps
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) anticorps
  • protein kinase D2 (Prkd2) anticorps
  • AI325941 anticorps
  • APKD2 anticorps
  • nPKC-D2 anticorps
  • Pc-2 anticorps
  • PC2 anticorps
  • PKD2 anticorps
  • PKD4 anticorps
  • PRKD2 anticorps
  • RGD1308054 anticorps
  • TRPP2 anticorps

Protein level used designations for anti-Protein Kinase D2 (PKD2) Anticorps

protein kinase D2 , serine/threonine-protein kinase D2-like , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystin-2 , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , serine/threonine-protein kinase D2 , nPKC-D2

GENE ID SPECIES
468929 Pan troglodytes
782793 Bos taurus
100407181 Callithrix jacchus
100471375 Ailuropoda melanoleuca
5311 Homo sapiens
25865 Homo sapiens
101540 Mus musculus
292658 Rattus norvegicus
484427 Canis lupus familiaris
100517036 Sus scrofa
100355908 Oryctolagus cuniculus
100717067 Cavia porcellus
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