Aperçu des produits pour anti-Desmoglein 2 (DSG2) Anticorps

Full name:
anti-Desmoglein 2 Anticorps (DSG2)
Chez www.anticorps-enligne.fr sont 178 Desmoglein 2 (DSG2) Anticorps de 26 de différents fournisseurs disponibles. De plus, nous expédions Desmoglein 2 Kits (11) et Desmoglein 2 Protéines (7) et beaucoup plus de produits pour cette protéine. Un total de 202 Desmoglein 2 produits sont actuellement listés.
Synonymes:
AA408168, ARVC10, ARVD10, CDHF5, CMD1BB, D18Ertd293e, dsc, DSG2, dsga, HDGC, si:dkeyp-51f12.6, wu:fj23f02

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anti-Desmoglein 2 Anticorps mieux référencés

  1. Cow (Bovine) Monoclonal Desmoglein 2 Primary Antibody pour IHC (fro), IF - ABIN111817 : Yang, Shaio, Wang, Wu, Stone: Neuroblastoma cell-mediated leukocyte chemotaxis: lineage-specific differentiation of interleukin-8 expression. dans Experimental cell research 1994 (PubMed)
    Show all 9 references for 111817

  2. Human Monoclonal Desmoglein 2 Primary Antibody pour FACS, IF - ABIN1106982 : Wahl: Generation of monoclonal antibodies specific for desmoglein family members. dans Hybridoma and hybridomics 2002 (PubMed)
    Show all 8 references for 1106982

  3. Human Monoclonal Desmoglein 2 Primary Antibody pour EIA, IHC (fro) - ABIN112136 : Franke, Nuber, Schmidt, Schäfer: Desmosomes--dual junctional principles of intra- and supracellular order in epithelial differentiation and tissue formation. dans Verhandlungen der Deutschen Gesellschaft für Pathologie 1995 (PubMed)
    Show all 6 references for 112136

  4. Human Monoclonal Desmoglein 2 Primary Antibody pour EIA, IHC (fro) - ABIN112242 : Demlehner, Schäfer, Grund, Franke: Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle. dans The Journal of cell biology 1995 (PubMed)
    Show all 3 references for 112242

  5. Human Polyclonal Desmoglein 2 Primary Antibody pour EIA, WB - ABIN360106 : Posch, Posch, Geier, Erdmann, Mueller, Richter, Ruppert, Pankuweit, Maisch, Perrot, Buttgereit, Dietz, Haverkamp, Ozcelik: A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy. dans Molecular genetics and metabolism 2008 (PubMed)
    Show all 2 references for 360106

  6. Cow (Bovine) Polyclonal Desmoglein 2 Primary Antibody pour IHC, WB - ABIN2782147 : Cirillo, Lanza, De Rosa, Cammarota, La Gatta, Gombos, Lanza: The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery. dans Journal of cellular biochemistry 2008 (PubMed)
    Show all 2 references for 2782147

  7. Human Monoclonal Desmoglein 2 Primary Antibody pour ICC, IF - ABIN1169682 : Keim, Johnson, Wheelock, Wahl: Generation and characterization of monoclonal antibodies against the proregion of human desmoglein-2. dans Hybridoma (2005) 2008 (PubMed)

Plus d’anticorps contre Desmoglein 2 partenaires d’interaction

Zebrafish Desmoglein 2 (DSG2) interaction partners

Human Desmoglein 2 (DSG2) interaction partners

  1. The homozygous desmoglein 2 variant c.1003A;G co-segregated with Arrhythmogenic right ventricular cardiomyopathy, indicating autosomal recessive inheritance and complete penetrance.

  2. these data suggest that palmitoylation of Dsg2 regulates protein transport to the plasma membrane. Modulation of the palmitoylation status of desmosomal cadherins can affect desmosome dynamics.

  3. Both Dsg2 mRNA and protein were highly expressed in non-small cell lung cancer (NSCLC) tissues and associated with NSCLC size, but not with overall survival of patients.

  4. a novel pathway of CSTA (Montrer CSTA Anticorps) regulation involving Dsg2

  5. DSG2 and DSG3 (Montrer DSG3 Anticorps) might be potential diagnostic markers for squamous cell carcinoma of the lung.

  6. In endometrial luminal epithelium, cadherin 6 (Montrer CDH6 Anticorps), desmoglein 2 and plexin b2 (Montrer PLXNB2 Anticorps) were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  7. a low DSG2 expression phenotype is a useful prognostic biomarker of tumor aggressiveness and may serve as an aid in identifying patients with clinically significant prostate cancer.

  8. Six variants of uncertain clinical significance in the PKP2 (Montrer PKP2 Anticorps), JUP (Montrer JUP Anticorps), and DSG2 genes showed a deleterious effect on mRNA splicing, indicating these are ARVD (Montrer TGFB3 Anticorps)/C-related pathogenic splice site mutations.

  9. This structure reveals that the ectodomain of Dsg2 is flexible even in the calcium-bound state and, on average, is shorter than the type 1 cadherin crystal structures.

  10. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (Montrer DSC2 Anticorps) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (Montrer EGFR Anticorps) signaling.

Mouse (Murine) Desmoglein 2 (DSG2) interaction partners

  1. Data suggest that loss of desmoglein 2 (Dsg2) compromises adhesion, and that this is a major pathogenic mechanism in DSG2-related and probably other desmosome-related arrhythmogenic cardiomyopathy (AC).

  2. Dsg2 modulates Gli1 (Montrer GLI1 Anticorps) expression. Dsg2-mediated hyperproliferation, MEK (Montrer MDK Anticorps)/Erk1/2 (Montrer MAPK1/3 Anticorps) activation, and accelerated squamous tumor development are enhanced on the Ptc1 (Montrer PTCH1 Anticorps)+/lacZ (Montrer GLB1 Anticorps) background.

  3. a novel pathway of CSTA (Montrer CSTA Anticorps) regulation involving Dsg2

  4. Data demonstrate that desmoglein-2 plays a critical role in cardiomyocyte cohesion and function.

  5. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (Montrer DSC2 Anticorps) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (Montrer EGFR Anticorps) signaling.

  6. Dsg2 compensates for Dsg3 (Montrer DSG3 Anticorps) depletion with regard to cell cohesion, but does not regulate p38 MAPK (Montrer MAPK14 Anticorps) signaling.

  7. In vivo interaction between Dsg2 and Na(V)1.5 provides a molecular pathway for the observed electrical disturbances during the early arrhythmogenic right ventricular cardiomyopathy.

  8. Mutant desmoglein 2 cannot support the increased requirements placed on intercalated disc adhesion during postnatal heart development. This induces cardiomyocyte death, aseptic inflammation and fibrotic replacement.

  9. ventricular arrhythmias that has been linked to mutations in desmosomal proteins including desmoglein 2

  10. Myocyte necrosis underlies progressive myocardial dystrophy in N271S-dsg2-related arrhythmogenic right ventricular cardiomyopathy.

Desmoglein 2 (DSG2) profil antigène

Antigen Summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Alternative names and synonyms associated with Desmoglein 2 (DSG2)

  • desmoglein 2 (DSG2) anticorps
  • desmoglein 2 (dsg2) anticorps
  • desmoglein 2 (LOC100348149) anticorps
  • desmoglein 2 (Dsg2) anticorps
  • AA408168 anticorps
  • ARVC10 anticorps
  • ARVD10 anticorps
  • CDHF5 anticorps
  • CMD1BB anticorps
  • D18Ertd293e anticorps
  • dsc anticorps
  • DSG2 anticorps
  • dsga anticorps
  • HDGC anticorps
  • si:dkeyp-51f12.6 anticorps
  • wu:fj23f02 anticorps

Protein level used designations for anti-Desmoglein 2 (DSG2) Anticorps

desmoglein 2 , Dsg alpha , desmocollin a , desmoglein-2-like , HDGC , cadherin family member 5 , desmoglein-2

GENE ID SPECIES
100066038 Equus caballus
428529 Gallus gallus
455356 Pan troglodytes
560026 Danio rerio
705805 Macaca mulatta
100348149 Oryctolagus cuniculus
100456327 Pongo abelii
100565052 Anolis carolinensis
1829 Homo sapiens
13511 Mus musculus
307562 Rattus norvegicus
490500 Canis lupus familiaris
100625833 Sus scrofa
508151 Bos taurus
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