Aperçu des produits pour SCRIB (SCRIB) Kits ELISA

Full name:
Scribbled Homolog (Drosophila) Kits ELISA (SCRIB)
Chez www.anticorps-enligne.fr sont 1 Scribbled Homolog (Drosophila) (SCRIB) Kits ELISA de 1 de différents fournisseurs disponibles. De plus, nous expédions SCRIB Anticorps (24) et et beaucoup plus de produits pour cette protéine. Un total de 28 SCRIB produits sont actuellement listés.
Synonymes:
0424/05, AI118201, CG5462, CG5467, CG31082, CG42614, CG43398, Crc, CRIB, CRIB1, CT17324, Dmel\\CG43398, Dmel_CG5462, Dmel_CG5467, Dmel_CG31082, Dmel_CG42614, ird, ird15, l(3)673, l(3)c00119, l(3)j7B3, l(3)S042405, MENE (3R)-F, mKIAA0147, Scb, SCR, scrb, SCRB1, Scrib, SCRIB1, scribble, scribble1, si:ch211-12p8.1, si:zc12p8.1, smi97B, vart, Vartul
list all ELISA KIts Gène GeneID UniProt
SCRIB 105782 Q80U72
Humain SCRIB SCRIB 23513 Q14160

Afficher toutes les espèces

Afficher tous les synonymes

SCRIB (SCRIB) Kits ELISA par réactivité

Select your species

Plus Kits ELISA pour SCRIB partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. the effects of loss of scrib and the modification of these effects via cooperative interactions that enhance the overall tumorigenic potential of scrib deficient cells, is reported.

  2. Knocking down scribble expression in either Mushroom body neurons or Dopaminergic neurons impairs normal memory loss.

  3. Our data reveal that the basolateral determinant Scribbled (Scrib) is required for PCV formation through optimizing BMP (Montrer TGFb Kits ELISA) signaling. Scrib regulates BMP (Montrer TGFb Kits ELISA)-type I receptor Thickveins (Tkv) localization at the basolateral region of PCV cells and subsequently facilitates Tkv internalization to Rab5 (Montrer RAB5A Kits ELISA) endosomes, where Tkv is active

  4. Scrib module regulates epithelial polarity by influencing endocytic itineraries of Crumbs and other retromer-dependent cargo.

  5. Loss of scrib, dlg (Montrer DLG4 Kits ELISA) and lgl had no effect on gonad formation, but Dlg (Montrer DLG4 Kits ELISA) and Scrib in the gonadal mesoderm acted critically in the somatic wrapping of the pole cells and the internal structure of the Drosophila embryonic gonads.

  6. Drosophila scrib acts downstream of the Fat (Ft) receptor, and requires Hippo signaling for its growth regulatory functions.

  7. Loss of Scrib promotes Yorkie (Montrer YAP1 Kits ELISA)/Scalloped-dependent epithelial tissue overgrowth, and this is also important for driving cooperative tumor overgrowth with oncogenic Ras-Raf (Montrer RAF1 Kits ELISA) signaling.

  8. Data show that mutations causing the loss of Salvador (Sav (Montrer SAV1 Kits ELISA)) or Scribble (Scrib) or activation of Ras transform normal stem cells into cancer stem cells through a multistep process in the adult Drosophila Malpighian tubules.

  9. interaction between Ras(V12) and scrib(-) clones involves JNK (Montrer MAPK8 Kits ELISA) signalling propagation and JNK (Montrer MAPK8 Kits ELISA)-induced upregulation of JAK (Montrer JAK3 Kits ELISA)/STAT (Montrer STAT1 Kits ELISA)-activating cytokines, a compensatory growth mechanism for tissue homeostasis

  10. These results demonstrate distinct aPKC and JNK (Montrer MAPK8 Kits ELISA)-dependent pathways through which loss of Scrib promotes tumourigenesis in Drosophila.

Mouse (Murine) Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. SCRIB is a positive regulator of mammary epithelial cell proliferation during pregnancy.

  2. Suggest a role for Plexin-B1 (Montrer PLXNB1 Kits ELISA) as a ligand and Sema4A (Montrer Sema4a Kits ELISA) as a receptor and characterize a reverse signaling pathway downstream of Sema4A (Montrer Sema4a Kits ELISA) regulating cell migration via Scrib.

  3. SCRIB uncouples reactive oxygen species-dependent bacterial killing activity from M1 polarization and inflammatory functions of macrophages

  4. we provide genetic evidence of a unique link between skin carcinogenesis and loss of the epithelial polarity regulator Scrib, emphasizing that Scrib exerts a wide-spread tumor suppressive function in epithelia.

  5. The polarity protein Scribble regulates myelination and remyelination in the central nervous system.

  6. Scrib is a regulator of tissue stem cells, controlling population expansion and self-renewal with Scrib expression dynamics directing satellite cell fate.

  7. Scrib is a novel proinflammatory regulator in endothelial cells, which maintains the protein expression of GATA-like protein-1.

  8. The Scrib-Rac1 interaction plays a crucial role in the organization of developing cardiomyocytes and formation of the ventricular myocardium.

  9. We show that loss of Scrib and activated oncogenic KRas cooperate in vivo, resulting in more aggressive lung tumors

  10. findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib loss activates a MAPK (Montrer MAPK1 Kits ELISA)/Fra1 (Montrer FOSL1 Kits ELISA) pathway that alters mammary progenitor activity

Zebrafish Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. Results demonstrate that anterior guidance decisions by commissural primary ascending (CoPA (Montrer COPA Kits ELISA)) axons are dependent on the function of planar cell polarity genes Fzd3a, Vangl2 (Montrer VANGL2 Kits ELISA) and Scribble both prior to and after midline crossing; experiments establish CoPA (Montrer COPA Kits ELISA) axons as a model system to investigate the mechanism of planar cell polarity signaling in commissural axon guidance.

  2. Zygotic expression of Scribble1 (scrb1) is required for migration of the nVII motor neurons mainly in a non cell-autonomous manner, while maternal expression is required for convergent extension movements during gastrulation.

  3. Suppression of scrib and puf60 in zebrafish (Montrer PUF60 Kits ELISA)leads to reduction in body length, small head size, and craniofacial defects.

  4. It was found that Scribble is required for oriented cell division and that its function in this process is independent of canonical apicobasal and planar polarity pathways.

  5. Lpp interacts with the PCP (Montrer PRCP Kits ELISA) protein Scrib in zebrafish, and that Lpp and Scrib cooperate for the mediation of convergence and extension.

  6. Scribble is a candidate link between Fat and the Hippo signaling cascade in vertebrates

Human Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. a new function for Scribble in Rho regulation that entails positioning of DLC3 (Montrer STARD8 Kits ELISA) GAP activity at cell junctions in polarized epithelial cells, is reported.

  2. Low Scribble expression in the primary breast tumor was correlated to prognosis in estrogen receptor (Montrer ESR1 Kits ELISA)-positive breast cancer patients.

  3. Suggest a role for Plexin-B1 (Montrer PLXNB1 Kits ELISA) as a ligand and Sema4A (Montrer Sema4a Kits ELISA) as a receptor and characterize a reverse signaling pathway downstream of Sema4A (Montrer Sema4a Kits ELISA) regulating cell migration via Scrib.

  4. SCRIB uncouples reactive oxygen species-dependent bacterial killing activity from M1 polarization and inflammatory functions of macrophages

  5. The Palmitoylation-deficient mutants of SCRIB were mislocalized, leading to disruption of cell polarity and loss of their tumor-suppressive activities to oncogenic YAP (Montrer YAP1 Kits ELISA), MAPK (Montrer MAPK1 Kits ELISA) and PI3K (Montrer PIK3CA Kits ELISA)/AKT (Montrer AKT1 Kits ELISA) pathways.

  6. Data show hepatitis C virus (HCV) nonstructural protein 4B (NS4B) PDZ (Montrer INADL Kits ELISA)-binding motif (PBM) promotes the colony formation of hepatoma cells by degrading human Scribble protein.

  7. the inclusion/exclusion of specific SCRIB exons is a mechanistic hallmark of breast cancer, which could potentially be exploited to develop more efficient diagnostics and therapies.

  8. loss of Scribble-induced HuR (Montrer ELAVL1 Kits ELISA) translocation mediates the accumulation of Snail (Montrer SNAI1 Kits ELISA) via activation of the p38 MAPK (Montrer MAPK14 Kits ELISA) pathway.

  9. The two PDZ (Montrer INADL Kits ELISA) domains within the PDZ34 tandem of Scribble, a cell polarity regulator, tightly pack in a 'front-to-back' mode to form a compact supramodule.

  10. We show that loss of Scrib and activated oncogenic KRas cooperate in vivo, resulting in more aggressive lung tumors

SCRIB profil antigène

Antigen Summary

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with SCRIB

  • scribbled (scrib) Elisa Kit
  • scribbled homolog (Drosophila) (Scrib) Elisa Kit
  • scribbled homolog (Drosophila) (scrib) Elisa Kit
  • scribbled planar cell polarity protein (SCRIB) Elisa Kit
  • 0424/05 Elisa Kit
  • AI118201 Elisa Kit
  • CG5462 Elisa Kit
  • CG5467 Elisa Kit
  • CG31082 Elisa Kit
  • CG42614 Elisa Kit
  • CG43398 Elisa Kit
  • Crc Elisa Kit
  • CRIB Elisa Kit
  • CRIB1 Elisa Kit
  • CT17324 Elisa Kit
  • Dmel\\CG43398 Elisa Kit
  • Dmel_CG5462 Elisa Kit
  • Dmel_CG5467 Elisa Kit
  • Dmel_CG31082 Elisa Kit
  • Dmel_CG42614 Elisa Kit
  • ird Elisa Kit
  • ird15 Elisa Kit
  • l(3)673 Elisa Kit
  • l(3)c00119 Elisa Kit
  • l(3)j7B3 Elisa Kit
  • l(3)S042405 Elisa Kit
  • MENE (3R)-F Elisa Kit
  • mKIAA0147 Elisa Kit
  • Scb Elisa Kit
  • SCR Elisa Kit
  • scrb Elisa Kit
  • SCRB1 Elisa Kit
  • Scrib Elisa Kit
  • SCRIB1 Elisa Kit
  • scribble Elisa Kit
  • scribble1 Elisa Kit
  • si:ch211-12p8.1 Elisa Kit
  • si:zc12p8.1 Elisa Kit
  • smi97B Elisa Kit
  • vart Elisa Kit
  • Vartul Elisa Kit

Protein level used designations for SCRIB

CG43398-PA , CG43398-PB , CG43398-PC , CG43398-PD , CG43398-PH , CG43398-PI , CG43398-PJ , CG43398-PK , CG43398-PL , CG43398-PM , CG43398-PN , CG43398-PO , CG43398-PP , CG43398-PQ , CG43398-PR , CG43398-PS , CG43398-PT , CG43398-PU , CG43398-PX , gp150-like , immune response deficient 15 , lethal (3) c00119 , scrib-PA , scrib-PB , scrib-PC , scrib-PD , scrib-PH , scrib-PI , scrib-PJ , scrib-PK , scrib-PL , scrib-PM , scrib-PN , scrib-PO , scrib-PP , scrib-PQ , scrib-PR , scrib-PS , scrib-PT , scrib-PU , scrib-PX , scribble , scribbles , smell impaired 97B , vartul , PDZ-domain protein scribble , circletail , protein scribble homolog , scribble homolog 1 , landlocked , llk , scribbled homolog

GENE ID SPECIES
44448 Drosophila melanogaster
105782 Mus musculus
368473 Danio rerio
23513 Homo sapiens
Fournisseurs de qualité sélectionnés pour SCRIB (SCRIB) Kits ELISA
Avez-vous cherché autre chose?