Aperçu des produits pour Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) Kits ELISA

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Protein Phosphatase 1, Regulatory Subunit 3A Kits ELISA (PPP1R3A)
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Synonymes:
GM, PP1G, PPP1R3, PPP1R3A, RG1, RGL
list all ELISA KIts Gène GeneID UniProt
Souris PPP1R3A PPP1R3A 140491 Q99MR9
Humain PPP1R3A PPP1R3A 5506 Q16821

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Plus Kits ELISA pour Protein Phosphatase 1, Regulatory Subunit 3A partenaires d'interaction

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results show that dysfunction of subunit PPP1R3A of protein phosphatase 1 (Montrer PPP1CB Kits ELISA) leads to weight gain, increased fat deposition and insulin (Montrer INS Kits ELISA) resistance

  2. Mice in which human PPP1R3A C1984DeltaAG replaced mouse PP1R3A had decreased muscle glycogen leve (Montrer GYS1 Kits ELISA)ls because failure of the trunc (Montrer GYS1 Kits ELISA)ated mutant to bind glycogen & colocalize with glycogen synthase (GS) decreased GS & increased glycogen phosphorylase activity.

  3. Backcrossing of G(M)-/- mice onto two different genetic backgrounds gave rise to lean, glucose-tolerant, insulin (Montrer INS Kits ELISA)-sensitive G(M)-/- mice indicating that at least one variant gene,is required for the development of the prediabetic phenotype of obese mice.

  4. Disruption of the Ppp1r3a gene does not result in either fat deposition or insulin (Montrer INS Kits ELISA) resistance, but PPP1r3a is essential for control of glycogen (Montrer GYS1 Kits ELISA) metabolism by exercise.

Human Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results demonstrate that hScrib (Montrer SCRIB Kits ELISA) acts as a scaffold to integrate the control of the PP1gamma and ERK (Montrer EPHB2 Kits ELISA) signaling pathways and explains how disruption of hScrib (Montrer SCRIB Kits ELISA) localisation can contribute towards the development of human malignancy

  2. A joint effect between the Asp905 and BMI increases the risk of type 2 diabetes, and Asp905Tyr and ARE polymorphism of PPP1R3 gene are not the major diabetogenic gene variants in Chinese population.

  3. We describe a family in which five individuals with severe insulin (Montrer INS Kits ELISA) resistance, but no unaffected family members, were compound heterozygous with respect to frameshift/premature stop mutations in two unlinked genes, PPARG (Montrer PPARG Kits ELISA) and PPP1R3A

  4. G(M) promotes glycogen (Montrer GYS1 Kits ELISA) storage and inversely regulates glycogen synthase and glycogen (Montrer GYS1 Kits ELISA) phosphorylase activities, while, specifically, synthase phosphatase activity of G(M)-PP1 (Montrer PPA1 Kits ELISA) is inhibited by glycogen (Montrer GYS1 Kits ELISA).

  5. Among the largest cohort of nondiabetic subjects (Caucasian, n = 112), the presence of the deletion allele (ARE-2) was associated with insulin (Montrer INS Kits ELISA) resistance and hyperandrogenemia.

  6. Inactivation of PPP1R3 gene is associated with tumor progression and metastasis of colorectal cancers

  7. PPP1R3A C1984DeltaAG (stop codon 668) isthe 1st prevalent mutation that directly impairs glycogen (Montrer GYS1 Kits ELISA) synthesis & decreases glycogen (Montrer GYS1 Kits ELISA) levels in human skeletal muscle. It is present in approximately 1 in 70 UK whites.

Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) profil antigène

Antigen Summary

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A)

  • protein phosphatase 1, regulatory (inhibitor) subunit 3A (Ppp1r3a) Elisa Kit
  • protein phosphatase 1, regulatory subunit 3A (PPP1R3A) Elisa Kit
  • protein phosphatase regulatory subunit (RG1) Elisa Kit
  • GM Elisa Kit
  • PP1G Elisa Kit
  • PPP1R3 Elisa Kit
  • PPP1R3A Elisa Kit
  • RG1 Elisa Kit
  • RGL Elisa Kit

Protein level used designations for PPP1R3A

protein phosphatase 1 glycogen-associated regulatory subunit , protein phosphatase 1 regulatory subunit 3A , protein phosphatase type-1 glycogen targeting subunit , RG1 , glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle , glycogen-associated regulatory subunit of protein phosphatase-1 , protein phosphatase 1 glycogen- associated regulatory subunit , protein phosphatase 1 regulatory subunit GM , protein phosphatase 1, regulatory (inhibitor) subunit 3A , serine /threonine specific protein phosphatase , type-1 protein phosphatase skeletal muscle glycogen targeting subunit

GENE ID SPECIES
140491 Mus musculus
5506 Homo sapiens
100009140 Oryctolagus cuniculus
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