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Human Fibronectin Kit ELISA pour Sandwich ELISA - ABIN411271
Tang, Song, Shi, Yuan, Li: Dicer knockdown induces fibronectin-1 expression in HEK293T cells via induction of Egr1. dans Biochimica et biophysica acta 2010
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Rat (Rattus) Fibronectin Kit ELISA pour Sandwich ELISA - ABIN411272
Owerbach, Doyle, Shows: Genetics of the large, external, transformation-sensitive (LETS) protein: assignment of a gene coding for expression of LETS to human chromosome 8. dans Proceedings of the National Academy of Sciences of the United States of America 1979
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Mouse (Murine) Fibronectin Kit ELISA pour Sandwich ELISA - ABIN921056
Gao, Huang, Li: NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. dans Molecular and cellular biochemistry 2013
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Rat (Rattus) Fibronectin Kit ELISA pour Sandwich ELISA - ABIN2684301
Kornblihtt, Umezawa, Vibe-Pedersen, Baralle: Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. dans The EMBO journal 1985
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Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.
Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage
Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.
Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.
reduction of fn1 function enables rescue of cardiac fusion in hand2 (Montrer HAND2 Kits ELISA) mutants
Fibronectin regulates epithelial organization during myocardial migration in zebrafish.
FN1 overexpression is an important determinant of thyroid cancer aggressiveness.
Thyroid hormone (Montrer PTH Kits ELISA) T3 induces fibronectin and HIF-1alpha (Montrer HIF1A Kits ELISA) synthesis via PI3K (Montrer PIK3CA Kits ELISA)/AKT (Montrer AKT1 Kits ELISA) signaling pathway.
Fibronectin and Hepatocyte Growth Factor (Montrer HGF Kits ELISA) were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion
Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (Montrer WWC1 Kits ELISA)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (Montrer CELSR3 Kits ELISA)), NIPBL (Montrer NIPBL Kits ELISA) (Nipped (Montrer RPL38 Kits ELISA)-B-like), and FN1 (fibronectin 1).
fibrillar fibronectin on this polymer, but not a globular conformation obtained on control polymers, promotes synergistic presentation of integrin-binding sites and bound bone morphogenetic protein 2 (BMP-2 (Montrer BMP2 Kits ELISA)), which enhances mesenchymal stem cell osteogenesis in vitro and drives full regeneration of a nonhealing bone defect in vivo at low GF concentrations.
Fn plays a critical role in inflammasome-activated cells by amplifying caspase-1 (Montrer CASP1 Kits ELISA) activation and inducing inflammatory cell death.
If the expression of Capon (Montrer NOS1AP Kits ELISA) is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon (Montrer NOS1AP Kits ELISA) in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells.
C-terminal truncation of transglutaminase 2 (TG2 (Montrer TGM2 Kits ELISA)) reduces binding to the small intestinal extracellular matrix (ECM (Montrer MMRN1 Kits ELISA)) despite retained fibronectin (FN)-binding capacity.
analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation
In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (Montrer ANGPT2 Kits ELISA) Ang-1 (Montrer ANGPT1 Kits ELISA), but not the receptor binding domain of Ang-2 (Montrer ANGPT2 Kits ELISA), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (Montrer MAPK1 Kits ELISA) signaling in the presence of both Ang-1 (Montrer ANGPT1 Kits ELISA) and fibronectin
fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities
The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (Montrer MAPK14 Kits ELISA) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.
scleraxis was required for TGFbeta-induced fibronectin expression: TGFbeta lost its ability to induce fibronectin expression following scleraxis knockdown.
The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (Montrer LGALS3 Kits ELISA) as opposed to fibronectin.
Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.
These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.
Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (Montrer GP6 Kits ELISA) and Toll-like receptor 4 (Montrer TLR4 Kits ELISA).
Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (Montrer NOTCH1 Kits ELISA) signaling.
A novel mechanism of transcriptional regulation of fibronectin through CREB (Montrer CREB1 Kits ELISA).
plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.
Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (Montrer TGFB1 Kits ELISA) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.
Putative function of fibronectin and its receptor (integrin alpha(5 (Montrer ITGA5 Kits ELISA))beta(1)) in male and female gametes during bovine fertilization in vitro.
These results highlight a crucial role for caveolin-1 (Montrer CAV1 Kits ELISA) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.
P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn
The expression of extracellular matrix molecules fibronectin and osteopontin (Montrer SPP1 Kits ELISA) in vitreous and retina samples in autoimmune uveitis was investigated.
The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.
The relationship between hyaluronan synthesis and levels of versican (Montrer Vcan Kits ELISA), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
fibronectin has a cryptic binding site for tenascin (Montrer TNC Kits ELISA)
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
, gene C
, cold-insoluble globulin
, migration-stimulating factor
, cumulus cell-specific fibronectin 1 transcript
, embryo-specific fibronectin 1 transcript
, fibronectin ED-A- region
, fibronectin variable region