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Aperçu des produits pour anti-FLASH (CASP8AP2) Anticorps

Full name:
anti-CASP8 Associated Protein 2 Anticorps (CASP8AP2)
Chez www.anticorps-enligne.fr sont 49 CASP8 Associated Protein 2 (CASP8AP2) Anticorps de 14 de différents fournisseurs disponibles. De plus, nous expédions FLASH Kits (7) et beaucoup plus de produits pour cette protéine. Un total de 59 FLASH produits sont actuellement listés.
Synonymes:
AA387232, CASP8AP2, CED-4, D4Ertd659e, fc74h10, FLASH, mKIAA1315, RIP25, wu:fc74h10, zgc:113449
afficher tous les anticorps Gène GeneID UniProt
CASP8AP2 9994 Q9UKL3
CASP8AP2 26885 Q9WUF3
CASP8AP2 313128  

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Réactivités les plus populaires pour anti-FLASH (CASP8AP2) Anticorps

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anti-Human FLASH Anticorps:

anti-Mouse (Murine) FLASH Anticorps:

anti-Rat (Rattus) FLASH Anticorps:

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anti-FLASH Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal FLASH Primary Antibody pour WB - ABIN2784233 : Lee, Pi, Lee: Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis. dans Biotechnology letters 2008 (PubMed)
    Show all 2 references for ABIN2784233

  2. Human Polyclonal FLASH Primary Antibody pour ICC, IF - ABIN4312087 : Chen, Evans, Evans: FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short. dans PLoS ONE 2012 (PubMed)

  3. Human Polyclonal FLASH Primary Antibody pour EIA, IF - ABIN499842 : Imai, Kimura, Murakami, Yajima, Sakamaki, Yonehara: The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. dans Nature 1999 (PubMed)

Plus d’anticorps contre FLASH partenaires d’interaction

Human CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. Our results indicate that the APAF1 (Montrer APAF1 Anticorps), BAX (Montrer BAX Anticorps), and FLASH genes not only harbor frameshift mutations but also demonstrate mutational ITH, which together might play a role in the tumorigenesis of CRC (Montrer CALR Anticorps) with MSI (Montrer MSI1 Anticorps)-H by affecting the apoptosis of cancer cells.

  2. High-quality solution NMR structures of three homeodomains from human proteins ALX4 (Montrer ALX4 Anticorps), ZHX1 (Montrer ZHX1 Anticorps) and CASP8AP2 were solved.

  3. the predictive values regarding low expressions of H2AFZ (Montrer H2AFZ Anticorps) and CASP8AP2 and high white blood cell count suggest that these features could help to identify more accurately patients at greater risk of relapse.

  4. ARS2 (Montrer SRRT Anticorps) and CASP8AP2 expressions can precisely predict high-risk of relapse and ALL prognosis.

  5. The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT (Montrer NPAT Anticorps) orthologues, thus acting as a signal targeting proteins to histone locus bodies.

  6. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (Montrer PML Anticorps) bodies.

  7. Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.

  8. FLASH/Lsm11 (Montrer LSM11 Anticorps) complex bind a unique combination of polyadenylation factors

  9. These data demonstrate that methylation within the Casp8AP2 promoter correlates with the development of drug resistance and might serve as a biomarker and treatment target for drug resistance in cancer cells.

  10. FLASH knockdown in HT1080 (Montrer CDC123 Anticorps) mutant cells defective in p53 (Montrer TP53 Anticorps) did not significantly accelerate Fas (Montrer FAS Anticorps) mediated apoptosis indicating that the effect was dependent on functional p53 (Montrer TP53 Anticorps).

Mouse (Murine) CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. the functional interaction of E2A (Montrer TCF3 Anticorps) and FLASH play an important role in cell proliferation and cellular senescence via regulation of p21 (Montrer D4S234E Anticorps) expression in experimental glomerulonephritis.

  2. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (Montrer PML Anticorps) bodies.

FLASH (CASP8AP2) profil antigène

Antigen Summary

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with FLASH (CASP8AP2)

  • caspase 8 associated protein 2 (CASP8AP2) anticorps
  • CASP8 associated protein 2 (casp8ap2) anticorps
  • CASP8 associated protein 2 (CASP8AP2) anticorps
  • CASP8 associated protein 2 (LOC100232114) anticorps
  • caspase 8 associated protein 2 (Casp8ap2) anticorps
  • AA387232 anticorps
  • CASP8AP2 anticorps
  • CED-4 anticorps
  • D4Ertd659e anticorps
  • fc74h10 anticorps
  • FLASH anticorps
  • mKIAA1315 anticorps
  • RIP25 anticorps
  • wu:fc74h10 anticorps
  • zgc:113449 anticorps

Protein level used designations for CASP8AP2

CASP8 associated protein 2 , caspase 8 associated protein 2 , CASP8-associated protein 2-like , CASP8-associated protein 2 , FLASH homolog RIP25 , FLICE associated huge , FLICE-associated huge protein , human FLASH

GENE ID SPECIES
421810 Gallus gallus
472070 Pan troglodytes
541521 Danio rerio
100065766 Equus caballus
100232114 Taeniopygia guttata
702294 Macaca mulatta
100342805 Oryctolagus cuniculus
100401726 Callithrix jacchus
100445558 Pongo abelii
100523759 Sus scrofa
9994 Homo sapiens
26885 Mus musculus
481921 Canis lupus familiaris
505138 Bos taurus
313128 Rattus norvegicus
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