Aperçu des produits pour anti-Aurora Kinase C (AURKC) Anticorps

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anti-Aurora Kinase C Anticorps (AURKC)
Chez www.anticorps-enligne.fr sont 126 Aurora Kinase C (AURKC) Anticorps de 16 de différents fournisseurs disponibles. De plus, nous expédions Aurora Kinase C Protéines (12) et beaucoup plus de produits pour cette protéine. Un total de 148 Aurora Kinase C produits sont actuellement listés.
Synonymes:
AIE1, AIE2, AIK3, ARK-3, ARK3, AurC, AURKC, aurora-C, IAK3, SPGF5, Stk13
afficher tous les anticorps Gène GeneID UniProt
AURKC 6795 Q9UQB9
AURKC 20871  
AURKC 292554  

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anti-Aurora Kinase C Anticorps mieux référencés

  1. Human Polyclonal Aurora Kinase C Primary Antibody pour WB - ABIN390979 : Burum-Auensen, Skotheim, Schjølberg, Røislien, Lothe, Clausen: Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. dans Journal of carcinogenesis 2010 (PubMed)
    Show all 4 references for 390979

  2. Human Polyclonal Aurora Kinase C Primary Antibody pour WB - ABIN1882164 : Kimura, Matsuda, Yoshioka, Okano: Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3. dans The Journal of biological chemistry 1999 (PubMed)
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  3. Human Polyclonal Aurora Kinase C Primary Antibody pour WB - ABIN390977 : Tseng, Chen, Hsu, Tang: Protein kinase profile of sperm and eggs: cloning and characterization of two novel testis-specific protein kinases (AIE1, AIE2) related to yeast and fly chromosome segregation regulators. dans DNA and cell biology 1998 (PubMed)
    Show all 3 references for 390977

  4. Cow (Bovine) Polyclonal Aurora Kinase C Primary Antibody pour WB - ABIN2785453 : Lee, Lim, Park, Lee, Han, Kim, Cheang, Lee, Lee, Ko, Jang, Kim, Miniaci, Bartsch, Kim, Bailey, Kandel, Kaang: Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia. dans Cell 2007 (PubMed)
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  5. Human Polyclonal Aurora Kinase C Primary Antibody pour WB - ABIN4890463 : Doyle, Lee, Selesniemi, Styer, Rueda: The impact of vitrification on murine germinal vesicle oocyte In vitro maturation and aurora kinase A protein expression. dans Journal of assisted reproduction and genetics 2014 (PubMed)

  6. Human Polyclonal Aurora Kinase C Primary Antibody pour ELISA, WB - ABIN4282476 : Dieterich, Zouari, Harbuz, Vialard, Martinez, Bellayou, Prisant, Zoghmar, Guichaoua, Koscinski, Kharouf, Noruzinia, Nadifi, Sefiani, Lornage, Zahi, Viville, Sèle, Jouk, Jacob, Escalier, Nikas et al.: The Aurora Kinase C c.144delC mutation causes meiosis I arrest in men and is frequent in the North African population. ... dans Human molecular genetics 2009 (PubMed)

Plus d’anticorps contre Aurora Kinase C partenaires d’interaction

Human Aurora Kinase C (AURKC) interaction partners

  1. Aurora-C interactions with members of the Chromosome Passenger Complex (CPC), Survivin (Montrer BIRC5 Anticorps) and Inner Centromere Protein (INCENP (Montrer INCENP Anticorps)) in reference to known Aurora-B (Montrer AURKB Anticorps) interactions to understand the functional significance of Aurora-C overexpression in human cancer cells, is reported.

  2. Patients presenting with a monomorphic teratozoospermia such as globozoospermia or macrospermia with more than 85% of the spermatozoa presenting this specific abnormality have been analyzed permitting to identify several key genes for spermatogenesis such as AURKC and DPY19L2 (Montrer DPY19L2 Anticorps).

  3. Homozygous c.144delC mutation in AURKC gene in infertile men with macrozoospermia in the Tunisian population

  4. AURKC mutations are more frequent than Klinefelter syndrome and constitute the leading genetic cause of infertility in North African men.

  5. Low AURKC expression is associated with cancer.

  6. Overexpression of AURKC is associated with breast tumors.

  7. Data indicate that the selective Aurora A (Montrer AURKA Anticorps), B, and C inhibitor SAR156497 showed antineoplastic activity in HCT116 cell xenograft model.

  8. This review will describe the functions of each Aurora kinase (Montrer AURKA Anticorps) which include Aurora A (AURKA (Montrer AURKA Anticorps)), Aurora B (AURKB (Montrer AURKB Anticorps)) and Aurora C (AURKC summarize their involvement in leukemia and discuss inhibitor development and efficacy in leukemia clinical trials

  9. Aberrantly expressed Aurora-C in somatic cancer cells may impair spindle checkpoint assembly by displacing the centromeric localization of chromosomal passenger complexes.

  10. Our data indicate that the AURKC c.144delC mutation has a relatively high carrier frequency in the Moroccan population.

Mouse (Murine) Aurora Kinase C (AURKC) interaction partners

  1. Three of these mutations AURKC c.144delC (AURKC p.L49Wfs22), AURKC c.686G > A (AURKC p.C229Y) and AURKC c.744C > G (AURKC p.Y248*) are the focus of this study. AURKC p.L49Wfs22 is a loss-of-function mutant that perturbs localization of the chromosomal passenger complex (CPC), AURKC p.C229Y is a hypomorph that cannot fully support cell-cycle progression, and AURKC p.Y248* fails to support chromosome segregation.

  2. These data uncover a role for haspin (Montrer GSG2 Anticorps) as a regulator of bipolar spindle assembly by regulating AURKC function at acentriolar microtubule-organizing centers in oocytes.

  3. these data suggest that mammalian oocytes contain AURKC to efficiently execute meiosis I and ensure high-quality eggs necessary for sexual reproduction.

  4. These findings suggest a model for the presence of AURKC in oocytes: that AURKC compensates for loss of AURKB (Montrer AURKB Anticorps) through differences in both message recruitment and protein stability.

  5. Overexpressed Aurora-C (aurkc) is an oncogene (Montrer RAB1A Anticorps). Overexpression of Aurora-C induces abnormal cell division resulting in centrosome amplification and multinucleation. Cells overexpressing active Aurora-C induced tumour formation.

  6. Conditional deletion of aurora B in somatic cells that do not express aurora C results in chromosomal misalignment and lack of chromosome segregation.

  7. Aurora-C, but not Aurora-B, plays essential roles in female mouse meiosis.

  8. role in regulating the cleavage furrow-specific vimentin (Montrer VIM Anticorps) phosphorylation in the cytokinetic process

  9. INCENP (Montrer INCENP Anticorps) recruits Aurora-C (or some other factor(s) recruit INCENP (Montrer INCENP Anticorps) and Aurora-C) to meiotic chromosomes, while Aurora-C may either work alone or cooperate with Aurora-B to regulate chromosome segregation during male meiosis

  10. Aurora-B and Aurora-C serve specialized functions in mammalian spermatogenesis.

Cow (Bovine) Aurora Kinase C (AURKC) interaction partners

  1. AURKB (Montrer AURKB Anticorps), AURKC, and Thr (Montrer TRH Anticorps)-phosphorylated AURKA (Montrer AURKA Anticorps) were detected at a contractile ring/midbody during the first polar body extrusion.

Aurora Kinase C (AURKC) profil antigène

Antigen Summary

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Aurora Kinase C (AURKC)

  • aurora kinase C (AURKC) anticorps
  • aurora kinase C (LOC100343856) anticorps
  • aurora kinase C (Aurkc) anticorps
  • aurora kinase C-like (LOC618599) anticorps
  • AIE1 anticorps
  • AIE2 anticorps
  • AIK3 anticorps
  • ARK-3 anticorps
  • ARK3 anticorps
  • AurC anticorps
  • AURKC anticorps
  • aurora-C anticorps
  • IAK3 anticorps
  • SPGF5 anticorps
  • Stk13 anticorps

Protein level used designations for anti-Aurora Kinase C (AURKC) Anticorps

aurora kinase C , ARK-3 , aurora 3 , aurora-related kinase 3 , aurora/IPL1-related kinase 3 , aurora/IPL1/EG2 protein 2 , serine/threonine kinase 13 (aurora/IPL1-like) , serine/threonine-protein kinase 13 , serine/threonine-protein kinase aurora-C , aurora B , aurora/Ipl1/Eg2 protein 1 , serine/threonine kinase 13 (aurora/IPL-like)

GENE ID SPECIES
740217 Pan troglodytes
100343856 Oryctolagus cuniculus
709801 Macaca mulatta
6795 Homo sapiens
20871 Mus musculus
292554 Rattus norvegicus
618599 Bos taurus
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