Aperçu des produits pour anti-HIPK2 (HIPK2) Anticorps

Full name:
anti-Homeodomain Interacting Protein Kinase 2 Anticorps (HIPK2)
Chez www.anticorps-enligne.fr sont 97 Homeodomain Interacting Protein Kinase 2 (HIPK2) Anticorps de 14 de différents fournisseurs disponibles. De plus, nous expédions HIPK2 Protéines (9) et HIPK2 Kits (4) et beaucoup plus de produits pour cette protéine. Un total de 115 HIPK2 produits sont actuellement listés.
Synonymes:
1110014O20Rik, B230339E18Rik, cb1009, HIPK2, MGC146781, PKM, PRO0593, si:dkey-16j24.2, si:dkey-239k7.1, Stank, wu:fk56d12

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anti-HIPK2 Anticorps mieux référencés

  1. Human Polyclonal HIPK2 Primary Antibody pour EIA - ABIN358542 : Guha, Chaerkady, Marimuthu, Patterson, Kashyap, Harsha, Sato, Bader, Lash, Minna, Pandey, Varmus: Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
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  2. Human Polyclonal HIPK2 Primary Antibody pour DB - ABIN389999 : Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. dans Molecular cell 2008 (PubMed)
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  3. Cow (Bovine) Polyclonal HIPK2 Primary Antibody pour IHC, WB - ABIN2779735 : Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300. dans Oncogene 2009 (PubMed)
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  4. Human Polyclonal HIPK2 Primary Antibody pour EIA, IHC (p) - ABIN359690 : Li, Wang, Debatin, Hug: The serine/threonine kinase HIPK2 interacts with TRADD, but not with CD95 or TNF-R1 in 293T cells. dans Biochemical and biophysical research communications 2000 (PubMed)
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  5. Human Polyclonal HIPK2 Primary Antibody pour EIA, WB - ABIN359691 : Kammeraat, Veldstra: Characterization of succinate semialdehyde dehydrogenase from rat brain. dans Biochimica et biophysica acta 1970 (PubMed)
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  6. Human Monoclonal HIPK2 Primary Antibody pour ELISA, WB - ABIN565400 : Esposito, Tornincasa, Chieffi, De Martino, Pierantoni, Fusco: High-mobility group A1 proteins regulate p53-mediated transcription of Bcl-2 gene. dans Cancer research 2010 (PubMed)

Plus d’anticorps contre HIPK2 partenaires d’interaction

Zebrafish Homeodomain Interacting Protein Kinase 2 (HIPK2) interaction partners

  1. Hipk2 promotes PP1c-mediated Dvl (Montrer DVL2 Anticorps) dephosphorylation via its C-terminal domain and is essential Dvl (Montrer DVL2 Anticorps) stability.

Human Homeodomain Interacting Protein Kinase 2 (HIPK2) interaction partners

  1. PARP1 (Montrer PARP1 Anticorps) can modulate the tumor-suppressing function of HIPK2 by regulating the protein stability of HIPK2.

  2. Data show that HIPK2-T566 phosphorylation contributes to UV-induced HIPK2 activity but it is dispensable for doxorubicin response.

  3. In this study, we report that the kinase HIPK2 is responsible for facilitating the Fbw7 (Montrer FBXW7 Anticorps)-dependent proteasomal degradation of Notch1 (Montrer NOTCH1 Anticorps) by phosphorylating its intracellular domain (Notch1 (Montrer NOTCH1 Anticorps)-IC) within the Cdc4 (Montrer FBXW7 Anticorps) phosphodegron motif.

  4. the migration and invasion of hepatocellular carcinoma cells were impaired by knockdown of histone deacetylase 5 (Montrer HDAC5 Anticorps) or hypoxia-inducible factor-1alpha but rescued when eliminating homeodomain-interacting protein kinase-2 in hepatocellular carcinoma cells, which suggested the critical role of histone deacetylase 5 (Montrer HDAC5 Anticorps)-homeodomain-interacting protein kinase-2-hypoxia-inducible factor-1alpha pathway in hypoxia-induced metastasis.

  5. These results suggest that the HIPK2-phospho-Ser271 CREB (Montrer CREB1 Anticorps) axis is a new arsenic-responsive CREB (Montrer CREB1 Anticorps) activation mechanism in parallel with the PKA-phospho-Ser133 CREB (Montrer CREB1 Anticorps) axis.

  6. Results demonstrated that HIPK2 may function as a novel regulator to modulate hepatic stellate cells activation, potentially by inhibiting the TGF-beta1 (Montrer TGFB1 Anticorps)/Smad3 (Montrer SMAD3 Anticorps) signaling pathway.

  7. Data show strong reduction of cell viability was induced in vitro and in vivo by the homeodomain interacting protein kinase 2 exon 8 spliced isoform (Hipk2-Deltae8)-specific siRNA, supporting a potential therapeutic application.

  8. Results indicate that Hipk2 exerts a relevant role in the survival of cerebellar Purkinje cells and that Hipk2 genetic ablation generates cerebellar dysfunction compatible with an ataxic-like phenotype.

  9. Our findings indicate that phosphorylation-dependent restriction of SIRT1 (Montrer SIRT1 Anticorps) activity by HIPK2 shapes the p53 (Montrer TP53 Anticorps) response

  10. The findings highlight a complex regulation of CREB-binding protein (Montrer CREBBP Anticorps) activity by HIPK2, which might be relevant for the control of specific sets of target genes involved in cellular proliferation, differentiation and apoptosis.

Mouse (Murine) Homeodomain Interacting Protein Kinase 2 (HIPK2) interaction partners

  1. Data show that HIPK2-T566 phosphorylation contributes to UV-induced HIPK2 activity but it is dispensable for doxorubicin response.

  2. reveal a previously unrecognized role of HIPK2 activation in ER-stress-mediated neurodegeneration and its potential role as a biomarker and therapeutic target for amyotrophic lateral sclerosis

  3. Results indicate that Hipk2 exerts a relevant role in the survival of cerebellar Purkinje cells and that Hipk2 genetic ablation generates cerebellar dysfunction compatible with an ataxic-like phenotype.

  4. HIPK2 is ubiquitinated upon heat shock.

  5. Phosphorylation of KLF3 (Montrer KLF3 Anticorps) and CtBP2 (Montrer CTBP2 Anticorps) by HIPK2 strengthens the interaction between these two factors and increases transcriptional repression by KLF3 (Montrer KLF3 Anticorps).

  6. Homeodomain-interacting protein kinase 2, a novel autoimmune regulator (Montrer AIRE Anticorps) interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells.

  7. Hipk2 has an essential role in mouse white fat development

  8. data identify Hipk2 as a novel regulator of C/EBPbeta (Montrer CEBPB Anticorps) and implicate different protein kinases in the cooperation of p300 (Montrer NOTCH1 Anticorps) with C/EBPbeta (Montrer CEBPB Anticorps) and C/EBPalpha (Montrer CEBPA Anticorps)

  9. Data indicate a critical kinase HIPK2 function in cytokinesis and in the prevention of tetraploidization.

  10. Hipk2 is a haploinsufficient tumor suppressor gene for mouse lymphoma development.

HIPK2 profil antigène

Antigen Summary

This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HIPK2

  • homeodomain interacting protein kinase 2 (HIPK2) anticorps
  • serine/threonine protein kinase (HIPK2) anticorps
  • homeodomain interacting protein kinase 2 (hipk2) anticorps
  • homeodomain interacting protein kinase 2 (Hipk2) anticorps
  • 1110014O20Rik anticorps
  • B230339E18Rik anticorps
  • cb1009 anticorps
  • HIPK2 anticorps
  • MGC146781 anticorps
  • PKM anticorps
  • PRO0593 anticorps
  • si:dkey-16j24.2 anticorps
  • si:dkey-239k7.1 anticorps
  • Stank anticorps
  • wu:fk56d12 anticorps

Protein level used designations for HIPK2

homeodomain interacting protein kinase 2 , serine/threonine protein kinase , homeodomain-interacting protein kinase 2-like , homeodomain-interacting protein kinase 2 , homeodomain-interacting protein kinase-2 , hHIPk2 , nuclear body-associated kinase 1 , sialophorin tail-associated nuclear serine/threonine-protein kinase , Mx-interacting protein kinase PKM

GENE ID SPECIES
716152 Macaca mulatta
8343557 Schistosoma mansoni
100064748 Equus caballus
100359086 Oryctolagus cuniculus
100406246 Callithrix jacchus
100436791 Pongo abelii
100463537 Ailuropoda melanoleuca
100566230 Anolis carolinensis
100585699 Nomascus leucogenys
463772 Pan troglodytes
495265 Xenopus laevis
510158 Bos taurus
557551 Danio rerio
780207 Xenopus (Silurana) tropicalis
28996 Homo sapiens
15258 Mus musculus
362342 Rattus norvegicus
374138 Gallus gallus
482772 Canis lupus familiaris
100627515 Sus scrofa
101842840 Mesocricetus auratus
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