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Aperçu des produits pour SMAD2 (SMAD2) Kits ELISA

Full name:
SMAD, Mothers Against DPP Homolog 2 Kits ELISA (SMAD2)
Chez sont 32 SMAD, Mothers Against DPP Homolog 2 (SMAD2) Kits ELISA de 10 de différents fournisseurs disponibles. De plus, nous expédions SMAD2 Anticorps (420) et SMAD2 Protéines (28) et beaucoup plus de produits pour cette protéine. Un total de 500 SMAD2 produits sont actuellement listés.
7120426M23Rik, fj43c06, hMAD-2, hSMAD2, JV18, JV18-1, Madh2, Madr2, mMad2, Smad-2, wu:fj43c06, Xmad2, XSmad2

SMAD2 Kits ELISA mieux référencés

  1. Human SMAD2 Kit ELISA pour Sandwich ELISA - ABIN417849 : Piotrowski, Kiszałkiewicz, Górski, Antczak, Górski, Pastuszak-Lewandoska, Migdalska-Sęk, Domańska-Senderowska, Nawrot, Czarnecka, Kurmanowska, Brzeziańska-Lasota: Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients. dans BMC immunology 2015 (PubMed)

  2. Rat (Rattus) SMAD2 Kit ELISA pour Sandwich ELISA - ABIN432538 : Kabel, Abd Elmaaboud, Albarraq: Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. dans Prostaglandins, leukotrienes, and essential fatty acids 2015 (PubMed)

Plus Kits ELISA pour SMAD2 partenaires d'interaction

Zebrafish SMAD, Mothers Against DPP Homolog 2 (SMAD2) interaction partners

  1. The results of this study found that Bptf and TGF-beta (Montrer TGFB1 Kits ELISA)/Smad2 mediate nucleosome remodeling to regulate wnt8a (Montrer WNT8A Kits ELISA) expression and hence neural posteriorization.

  2. Smad2 and Eomesodermin (Montrer EOMES Kits ELISA) a (Eomesa (Montrer EOMES Kits ELISA)) bind common genomic regions proximal to genes involved in mesoderm and endoderm formation, suggesting Eomesa (Montrer EOMES Kits ELISA) forms a general component of the Smad2 signalling complex in zebrafish.

  3. These results reveal that kinesin-mediated transport of Smad2 along microtubules to the receptors is an essential step in ligand-induced Smad2 activation.

  4. study systemically uncovers a large number of Smad2 targets in early gastrulas and suggests cooperative roles of Smad2 and other transcription factors in controlling target gene transcription

  5. Nodal signaling and mesendoderm induction depend on Smad2/3 and suggest that transforming growth factor-beta signals other than Nodal also contribute to Smad2/3 signaling and embryonic patterning.

  6. Smad2/3 activities play important roles not only in mesendodermal development but also in neural development during early vertebrate embryogenesis

Human SMAD, Mothers Against DPP Homolog 2 (SMAD2) interaction partners

  1. overexpression of miR29b markedly reduced the expression levels of COL1A1 (Montrer COL1A1 Kits ELISA) and alphaSMA (Montrer ACTA2 Kits ELISA), and decreased the expression and nuclear accumulation of pSmad2/3.

  2. p-SMAD2/3 proteins were remarkably increased in bladder carcinoma. High p-SMAD2/3 was not statistically associated with clinicopathological characteristics of the patients. Overexpression of hepaCAM (Montrer HEPACAM Kits ELISA) prevented the p-SMAD2/3 translocation from the cytoplasm to the nucleus in bladder cancer cells. The p-SMAD2/3 pathway is critical for hepaCAM (Montrer HEPACAM Kits ELISA)-induced cancer cell apoptosis.

  3. silencing NLRC5 (Montrer NLRC5 Kits ELISA) reduced extracellular matrix expression in keloid fibroblasts through inhibiting the TGF-beta1 (Montrer TGFB1 Kits ELISA)/Smad (Montrer SMAD1 Kits ELISA) signaling pathway.

  4. Data indicate the TGF-beta (Montrer TGFB1 Kits ELISA) pathway regulates the epithelial-to-mesenchymal transition (EMT (Montrer ITK Kits ELISA)) of gastric cancer cells by increasing the levels of microRNA miRNA-181b to target Timp3 (Montrer TIMP3 Kits ELISA) via the Smad2/3/4-dependent pathway.

  5. GDF-9 (Montrer GDF9 Kits ELISA) promotes the proliferation and migration of keloid fibroblasts via a mechanism involving the Smad2/3 pathway.

  6. High expression of p-Smad2 is associated with glioma.

  7. The data showed that the effect of Activin A (Montrer INHBA Kits ELISA) on ESCs (Montrer NR2E3 Kits ELISA) was partially abrogated by pretreatment with an inhibitor of ALK4 (Montrer ACVR1B Kits ELISA) (the type I receptor, ActRIB (Montrer ACVR1B Kits ELISA)) and Smad4 (Montrer SMAD4 Kits ELISA)-siRNA. Cumulatively, these data suggest that Activin A (Montrer INHBA Kits ELISA) promotes the secretion of estradiol from ESCs (Montrer NR2E3 Kits ELISA) by increasing the expression of P450arom (Montrer CYP19A1 Kits ELISA) via the ALK4 (Montrer ACVR1B Kits ELISA)-Smad (Montrer SMAD1 Kits ELISA) pathway. These findings indicate the ALK4 (Montrer ACVR1B Kits ELISA)-Smad (Montrer SMAD1 Kits ELISA) pathway may promote ectopic lesion survival and developmen

  8. miR (Montrer MLXIP Kits ELISA)-128 regulates the differentiation of human hair follicle mesenchymal stem cells into smooth muscle cells via targeting SMAD2, a main transcription regulator in TGF-beta (Montrer TGFB1 Kits ELISA) signaling pathway involving smooth muscle cell differentiation.

  9. Smad2 and Smad3 (Montrer SMAD3 Kits ELISA) possess differential sensitivities in relaying TGFbeta (Montrer TGFB1 Kits ELISA) signaling and have distinct roles in regulating early developmental events.

  10. Results provide evidence that miR (Montrer MLXIP Kits ELISA)-148a decreases the expression of TGFbeta2 and SMAD2 in gastric cancer cells through binding to their 3'UTRs.

Xenopus laevis SMAD, Mothers Against DPP Homolog 2 (SMAD2) interaction partners

  1. E2a (Montrer TCF3 Kits ELISA) is necessary to drive transcription of Smad2/3 target genes, including critical regulators of dorsal cell fate and morphogenesis

  2. GDF11 (Montrer GDF11 Kits ELISA) has a central role in the activation of Smad2 phosphorylation in tailbud stage Xenopus embryos.

  3. XPIASy functions as an essential negative regulator of the XSmad2 pathway to ensure proper mesoderm induction at the appropriate time and in the appropriate region.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 2 (SMAD2) interaction partners

  1. the present work provides evidence supporting a functional role of SMAD2/3 in bovine early embryogenesis

  2. Mechanical compression not only with physiological but also with excessive stress can activate Smad2/3P signaling, which is known to be protective for articular cartilage and to block chondrocyte terminal differentiation.

  3. a detailed computational model for TGF-beta (Montrer TGFB1 Kits ELISA) signalling that incorporates elements of previous models together with crosstalking between Smad1 (Montrer SMAD1 Kits ELISA)/5/8 and Smad2/3 channels through a negative feedback loop dependent on Smad7 (Montrer SMAD7 Kits ELISA).

Mouse (Murine) SMAD, Mothers Against DPP Homolog 2 (SMAD2) interaction partners

  1. This study found evidence of increased leukocyte phosphorylated-Smad2/3 staining in both single leukocytes and platelet-leukocyte aggregates in mice that developed aortic valve stenosis, suggesting the presence of increased circulating active TGF-beta1 (Montrer TGFB1 Kits ELISA).

  2. Data show that muscle-specific (Montrer EIF3K Kits ELISA) Smad (Montrer SMAD1 Kits ELISA) proteins Smad2/3-deficient mice exhibited significant resistance to denervation-induced muscle atrophy.

  3. these data demonstrate that the SMI drives ES cells to skeletal muscle via concerted activation of the Wnt (Montrer WNT2 Kits ELISA) pathway, and inhibition of Smad2/3 signaling and Shh (Montrer SHH Kits ELISA) pathways.

  4. Arsenite disrupts zinc-dependent TGFbeta2-SMAD2/3 activity during murine cardiac progenitor cell differentiation.

  5. Smad2 and Smad3 (Montrer SMAD3 Kits ELISA) oppositely modify STAT3 (Montrer STAT3 Kits ELISA)-induced transcription of IL-17A (Montrer IL17A Kits ELISA) and retinoic acid receptor (Montrer RARA Kits ELISA)-related orphan nuclear receptor (Montrer NR1D1 Kits ELISA), RORgammat encoded by Rorc (Montrer RORC Kits ELISA), by acting as a co-activator and co-repressor of STAT3 (Montrer STAT3 Kits ELISA), respectively.

  6. Endoplasmic reticulum stress in hepatic stellar cells promotes liver fibrosis by inducing over expression of SMAD2.

  7. pSmad3L-Ser (Montrer SIGLEC1 Kits ELISA) signalling correlates with carcinogenesis of colon tumors and this work supports the hypothesis that pSmad2/3L-Thr (Montrer TRH Kits ELISA) immunostaining-positive cells are cancer stem cells.

  8. These results suggest that TGF-beta regulates RANKL-induced osteoclastogenesis through reciprocal cooperation between Smad2/3 and c-Fos.

  9. Treatment with geniposide almost completely blocked the phosphorylation of Smad2/3, extracellular signal-regulated kinase (ERK (Montrer EPHB2 Kits ELISA)) and Akt (Montrer AKT1 Kits ELISA) in AML12 cells.

  10. Deficiency of MKP5 (Montrer DUSP10 Kits ELISA) resulted in increased inflammatory activation in macrophages. These findings thus demonstrate that MKP5 (Montrer DUSP10 Kits ELISA) critically controls inflammation in white adipose tissue and the development of metabolic disorders

SMAD2 profil antigène

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with SMAD2

  • SMAD family member 2 (SMAD2) Elisa Kit
  • SMAD family member 2 (smad2) Elisa Kit
  • MAD homolog 2 (Drosophila) (smad2) Elisa Kit
  • SMAD family member 2 (Smad2) Elisa Kit
  • 7120426M23Rik Elisa Kit
  • fj43c06 Elisa Kit
  • hMAD-2 Elisa Kit
  • hSMAD2 Elisa Kit
  • JV18 Elisa Kit
  • JV18-1 Elisa Kit
  • Madh2 Elisa Kit
  • Madr2 Elisa Kit
  • mMad2 Elisa Kit
  • Smad-2 Elisa Kit
  • wu:fj43c06 Elisa Kit
  • Xmad2 Elisa Kit
  • XSmad2 Elisa Kit

Protein level used designations for SMAD2

SMAD, mothers against DPP homolog 2 , MAD (mothers against decapentaplegic, Drosophila) homolog 2 , SMA- and MAD-related protein 2 , SMAD 2 , SMAD family member 2 , mothers against DPP homolog 2 , mothers against decapentaplegic homolog 2 , MAD homolog 2 , Sma- and Mad-related protein 2 , mother against DPP homolog 2 , mothers against decapentaplegic-like 2 , Smad 2 , mad-related protein 2

100033843 Equus caballus
496586 Xenopus (Silurana) tropicalis
30639 Danio rerio
4087 Homo sapiens
432023 Xenopus laevis
395247 Gallus gallus
480144 Canis lupus familiaris
100155304 Sus scrofa
516010 Bos taurus
17126 Mus musculus
29357 Rattus norvegicus
455407 Pan troglodytes
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