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Lipopolysaccharide/tumor necrosis factor-alpha (Montrer TNF Kits ELISA) treatment increased the expression of iNOS (Montrer NOS2 Kits ELISA), arginase II (Montrer ARG2 Kits ELISA), CAT-1, and CAT-2 (Montrer SLC7A2 Kits ELISA) mRNA.
Estradiol increases arginine transport and CAT-1 (Montrer CRAT Kits ELISA) activity through modulation of constitutive signaling transduction pathways involving ERK (Montrer EPHB2 Kits ELISA). Progesterone inhibits arginine transport and CAT-1 (Montrer CRAT Kits ELISA) via both PKCalpha (Montrer PKCa Kits ELISA) and ERK1/2 (Montrer MAPK1/3 Kits ELISA) phosphorylation.
The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.
Overexpression of arginine transporter CAT-1 (Montrer CRAT Kits ELISA) is associated with accumulation of L-arginine (Montrer GATM Kits ELISA) and cell growth in human colorectal cancer tissue.
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
mRNA levels for high-affini (Montrer CRAT Kits ELISA)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (Montrer DMD Kits ELISA)d 32% in mdx and transgenic mdx:utr mice respectively.
The data demonstrates that CAT1 (Montrer CRAT Kits ELISA) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.
In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (Montrer CRAT Kits ELISA) resulted in significantly greater L-arginine (Montrer GATM Kits ELISA) transport and NO production
In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (Montrer DDAH1 Kits ELISA)/CAT-1 (Montrer CRAT Kits ELISA) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.
Insulin (Montrer INS Kits ELISA) increased hCATs-L-arginine (Montrer GATM Kits ELISA) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (Montrer PSG1 Kits ELISA) nuclear protein (Montrer RDBP Kits ELISA) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (Montrer INS Kits ELISA).
Data show that the CAT-1 (Montrer CRAT Kits ELISA) isoform plays a role in arginine uptake.
Arginine supplementation enhances small intestinal expression of SLC7A7 (Montrer Slc7a7 Kits ELISA) and SLC7A1.
Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.
Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.
Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11
Study showed that TRPV6 (Montrer TRPV6 Kits ELISA)-expressing elements seem to be discretely organized in the brain of mouse. TRPV6 (Montrer TRPV6 Kits ELISA)-immunoreactive arcuate neurons co-express estrogen receptor alpha (Montrer ESR1 Kits ELISA) and the ion channel protein (Montrer TRPC3 Kits ELISA) expression in the mediobasal hypothalamus showed correlation with estrous cycle.
TRPV6 (Montrer TRPV6 Kits ELISA)-/- mice spontaneously developed osteoarthritis at a younger age and had more severe manifestations of OA than wild-type controls. TRPV6 (Montrer TRPV6 Kits ELISA) could regulate certain chondrocyte functions, including ECM (Montrer MMRN1 Kits ELISA) secretion, cell proliferation, and apoptosis.
A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.
TRPV6 (Montrer TRPV6 Kits ELISA) plays an essential role in bone metabolism and is a critical regulator in osteoclasts differentiation and bone resorption.
CAT1 overexpression prevents obesity-induced hypertension by reducing the influence of the SNS (Montrer SCN10A Kits ELISA) on the maintenance of arterial pressure but not by buffering pressor responses to stress.
Adra2a (Montrer ADRA2A Kits ELISA) is expressed in the mesenchyme of the mouse stomach primordium at E11.5. Fzd5 and Trpv6 (Montrer TRPV6 Kits ELISA) are expressed in the epithelial layer of the stomach primordium after E11.5.
Endothelial CAT-1 overexpression can counter the ability of oxidative stress.
focus on TRPV6 (Montrer TRPV6 Kits ELISA) gene polymorphisms, the start of TRPV6 (Montrer TRPV6 Kits ELISA) translation at a non-AUG codon and the functions of TRPV6 (Montrer TRPV6 Kits ELISA) in intestinal Ca(2 (Montrer CA2 Kits ELISA)+) uptake, sperm maturation, and male fertility.
these data indicate that obesity-induced down-regulation of CAT1 expression and subsequent reduced bioavailability of nitric oxide may contribute to the development of obesity-induced hypertension.
Fibroblasts from two long-lived mice mutants (Snell dwarf (Montrer POU1F1 Kits ELISA) and PAPP-A (Montrer PAPPA Kits ELISA) knockout) expressed higher levels of CAT1 (a ATF4 (Montrer ATF4 Kits ELISA) target gene) during stress, suggesting a connection to longevity.
acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system
high affinity cationic amino acid transporter 1
, cationic amino acid transporter 1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
, solute carrier family 7 member 1
, system Y+ basic amino acid transporter
, high affinity cationic amino acid transporter 1-like
, amino acid transporter, cationic 1
, ecotropic retroviral leukemia receptor homolog
, ecotropic retroviral receptor
, ecotropic retrovirus receptor homolog
, cationic amino acid transporter-1
, ecotropic retroviral leukemia receptor
, ecotropic retrovirus receptor
, Solute carrier family 7 member A1 (amino acid transporter cationic 1)
, cationic amino acid transporter, y+ system
, cationinc amino acid transporter 1
, solute carrier family 7, member 1
, calcium transport protein 1
, epithelial calcium channel 2
, osmosensitive transient receptor potential channel 3
, transient receptor potential cation channel subfamily V member 6