Aperçu des produits pour SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Kits ELISA

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SH3-Domain Kinase Binding Protein 1 Kits ELISA (SH3KBP1)
Chez www.anticorps-enligne.fr sont 0 SH3-Domain Kinase Binding Protein 1 (SH3KBP1) Kits ELISA de de différents fournisseurs disponibles. De plus, nous expédions SH3-Domain Kinase Binding Protein 1 Anticorps (42) et SH3-Domain Kinase Binding Protein 1 Protéines (9) et beaucoup plus de produits pour cette protéine. Un total de 54 SH3-Domain Kinase Binding Protein 1 produits sont actuellement listés.
1200007H22Rik, 1700125L08Rik, 5830464D22Rik, AI447724, CD2BP3, CIN85, GIG10, HSB-1, HSB1, IN85, MIG18, Ruk, Seta
list all ELISA KIts Gène GeneID UniProt
Humain SH3KBP1 SH3KBP1 30011 Q96B97
Souris SH3KBP1 SH3KBP1 58194 Q8R550
Rat SH3KBP1 SH3KBP1 84357 Q925Q9

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Plus Kits ELISA pour SH3-Domain Kinase Binding Protein 1 partenaires d'interaction

Human SH3-Domain Kinase Binding Protein 1 (SH3KBP1) interaction partners

  1. these data support a role for the novel PP2Ac-CIN85 complex in supporting integrin-dependent platelet function by dampening the phosphatase activity.

  2. CIN85 promotes recycling of TGF-beta (Montrer TGFB1 Kits ELISA) receptors and thereby positively regulates TGF-beta (Montrer TGFB1 Kits ELISA) signaling.

  3. we demonstrate that SEPT9 (Montrer SEPT9 Kits ELISA) negatively regulates EGFR (Montrer EGFR Kits ELISA) degradation by preventing the association of the ubiquitin ligase Cbl (Montrer CBL Kits ELISA) with CIN85, resulting in reduced EGFR (Montrer EGFR Kits ELISA) ubiquitylation

  4. Results support the model that Cbl (Montrer CBL Kits ELISA)-CIN85-endophilin complex is not required for efficient internalization of EGFR (Montrer EGFR Kits ELISA), a prototype RTK.

  5. Multiple molecular forms of adaptor protein Ruk/CIN85 specifically associate with different subcellular compartments in human breast adenocarcinoma cell line.

  6. LOX (Montrer LOX Kits ELISA)-PP interacts with CIN85 via a novel SH3-binding motif and this association reduces CIN85-promoted invasion by breast cancer cells.

  7. an FRS2beta (Montrer FRS3 Kits ELISA)-CIN85/CD2AP (Montrer Cd2ap Kits ELISA)-Cbl (Montrer CBL Kits ELISA) axis for downregulation of ErbB2 (Montrer ERBB2 Kits ELISA) may regulate ErbB2 (Montrer ERBB2 Kits ELISA) protein levels in physiological and pathological settings

  8. Data show that EGFR (Montrer EGFR Kits ELISA) activation leads to a pronounced src (Montrer SRC Kits ELISA)-mediated tyrosine phosphorylation of CIN85 that subsequently influences EGFR (Montrer EGFR Kits ELISA) ubiquitination.

  9. this study indicates that high levels of Ruk(l)/CIN85 contribute to the conversion of breast adenocarcinoma cells into a more malignant phenotype via modulation of the Src (Montrer SRC Kits ELISA)/Akt (Montrer AKT1 Kits ELISA) pathway.

  10. Data show that CIN85 (c-Cbl interacting protein of 85 kDa) is constitutively associated with c-Cbl (Montrer CBL Kits ELISA), Cbl-b, and B-cell linker (Montrer BLNK Kits ELISA) in B cells.

Mouse (Murine) SH3-Domain Kinase Binding Protein 1 (SH3KBP1) interaction partners

  1. CIN85/RukL is involved in endocytosis of nephrin (Montrer NPHS1 Kits ELISA) in podocytes under diabetic conditions, causing podocyte depletion and promoting proteinuria. CIN85/RukL expression therefore shows potential to be a novel target for antiproteinuric therapy in diabetes.

  2. Dab1 (Montrer DAB1 Kits ELISA) mediated the association of CIN85 with ApoER2 (Montrer LRP8 Kits ELISA) or VLDLR (Montrer VLDLR Kits ELISA) in neurons.

  3. Data suggest that Ser587 Cin85 phosphomimetic mutant protein shows dramatically reduced binding to Dab1 (Montrer DAB1 Kits ELISA) (disabled protein 1) (without affecting binding to CapZ (Montrer CAPZA1 Kits ELISA)).

  4. Sh3kbp1 is SUMOylated by SUMO-1 (Montrer SUMO1 Kits ELISA), -2, and -3 and that SUMOylation is enhanced in the presence of Cd2ap (Montrer Cd2ap Kits ELISA).

  5. the interaction between SHIP-1 (Montrer INPP5D Kits ELISA) and CIN85 might synergistically facilitate the down-regulation of phosphatidylinositol-3,4,5-trisphosphate levels.

  6. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 (Montrer BLNK Kits ELISA) and CIN85 are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  7. a B cell-specific deletion of CIN85 led to impaired T cell-independent type II antibody responses in vivo and diminished IKK-beta (Montrer IKBKB Kits ELISA) activation and cellular responses to B (Montrer TDO2 Kits ELISA) cell receptor cross-linking in vitro

  8. Coexpression of CIN85/Ruk(L) with CD2AP (Montrer Cd2ap Kits ELISA) led to a decreased binding of CIN85/Ruk(L) to nephrin (Montrer NPHS1 Kits ELISA) and podocin, which indicates a functional competition between CD2AP (Montrer Cd2ap Kits ELISA) and CIN85/Ruk(L).

  9. Data indicate an important function of CIN85 (SH3KBP1) in the regulation of dopamine D2 receptor (Montrer DRD2 Kits ELISA) functions and provide a molecular explanation for the hyperactive behaviour of CIN85(Deltaex2) mice.

  10. CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

SH3-Domain Kinase Binding Protein 1 (SH3KBP1) profil antigène

Antigen Summary

This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with SH3-Domain Kinase Binding Protein 1 (SH3KBP1)

  • SH3-domain kinase binding protein 1 (SH3KBP1) Elisa Kit
  • SH3-domain kinase binding protein 1 (sh3kbp1) Elisa Kit
  • SH3-domain kinase binding protein 1 (Sh3kbp1) Elisa Kit
  • 1200007H22Rik Elisa Kit
  • 1700125L08Rik Elisa Kit
  • 5830464D22Rik Elisa Kit
  • AI447724 Elisa Kit
  • CD2BP3 Elisa Kit
  • CIN85 Elisa Kit
  • GIG10 Elisa Kit
  • HSB-1 Elisa Kit
  • HSB1 Elisa Kit
  • IN85 Elisa Kit
  • MIG18 Elisa Kit
  • Ruk Elisa Kit
  • Seta Elisa Kit

Protein level used designations for SH3KBP1

SH3-domain kinase binding protein 1 , SH3 domain-containing kinase-binding protein 1-like , CD2-binding protein 3 , SH3 domain-containing kinase-binding protein 1 , Src family kinase-binding protein 1 , c-Cbl-interacting protein , cbl-interacting protein of 85 kDa , human Src family kinase-binding protein 1 , migration-inducing gene 18 , src-related kinase binding protein-1 , SH3-containing, expressed in tumorigenic astrocytes , Sh3 containing, expressed in astrocytes , regulator of ubiquitous kinase , SH3 domain-containing adapter protein , ruk

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