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Aperçu des produits pour anti-DACH1 (DACH1) Anticorps

Full name:
anti-Dachshund Homolog 1 (Drosophila) Anticorps (DACH1)
Chez www.anticorps-enligne.fr sont 75 Dachshund Homolog 1 (Drosophila) (DACH1) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions DACH1 Protéines (3) et DACH1 Kits (2) et beaucoup plus de produits pour cette protéine. Un total de 86 DACH1 produits sont actuellement listés.
Synonymes:
AI182278, Dac, DACH, E130112M23Rik, zgc:158869
afficher tous les anticorps Gène GeneID UniProt
DACH1 13134 Q9QYB2
DACH1 1602 Q9UI36
DACH1    

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Réactivités les plus populaires pour anti-DACH1 (DACH1) Anticorps

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anti-Mouse (Murine) DACH1 Anticorps:

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anti-DACH1 Anticorps mieux référencés

  1. Human Polyclonal DACH1 Primary Antibody pour ICC, IF - ABIN4304211 : Powe, Dhondalay, Lemetre, Allen, Habashy, Ellis, Rees, Ball: DACH1: its role as a classifier of long term good prognosis in luminal breast cancer. dans PLoS ONE 2014 (PubMed)
    Show all 4 references for ABIN4304211

  2. Human Polyclonal DACH1 Primary Antibody pour WB - ABIN2778443 : Wu, Katiyar, Li, Liu, Ju, Popov, Jiao, Lisanti, Casola, Pestell: Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal DACH1 Primary Antibody pour ELISA, WB - ABIN314239 : Wu, Yang, Wang, Davoli, DAmico, Li, Cveklova, Kozmik, Lisanti, Russell, Cvekl, Pestell: DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. dans The Journal of biological chemistry 2003 (PubMed)

Plus d’anticorps contre DACH1 partenaires d’interaction

Mouse (Murine) Dachshund Homolog 1 (Drosophila) (DACH1) interaction partners

  1. The results of this study suggested the involvement of the mouse Dach1 gene in adult neurogenesis; cells expressing this gene exhibit the properties of adult NSCs or neuroblasts and respond to MCAo by enhanced neurogenesis.

  2. find that in cells growing in IGF-1 (Montrer IGF1 Anticorps) (and unresponsive to EGF (Montrer EGF Anticorps)), DACH1 is devoid of tumor suppressor activity

  3. The mouse dachshund gene is related to the Ski (Montrer SKI Anticorps) proto-oncogene (Montrer RAB1A Anticorps) and is expressed in eye and limb.

  4. In the mouse, Dach1 expression in the developing ear also overlaps with the expression of Eya1 (Montrer EYA1 Anticorps) (an eya homologue)

  5. Dach1 is a target gene of FGF signaling during limb skeletal development, and Dach1 may function as an intermediary in the FGF signaling pathway regulating cell proliferation or differentiation

  6. Dach1 is critical for postnatal survival of mice

  7. The phosphatase function of Eya switches the function of Six1 (Montrer SIX1 Anticorps)-Dach from repression to activation, causing transcriptional activation through recruitment of co-activators

  8. The Pax (Montrer PXN Anticorps)-Eya-Six-Dach network is at best only partly conserved during lens and nasal placode development.

  9. DACH1 repressed cyclin D1 (Montrer CCND1 Anticorps) through a novel mechanism via a c-Jun (Montrer JUN Anticorps) DNA-binding partner, requiring the DACH1 alpha-helical DS domain which recruits corepressors to the local chromatin.

  10. These studies demonstrate a novel mechanism by which DACH1 blocks c-Jun (Montrer JUN Anticorps)-mediated contact-independent growth through repressing the c-Jun (Montrer JUN Anticorps) delta domain.

Human Dachshund Homolog 1 (Drosophila) (DACH1) interaction partners

  1. DACH1 expression regulates the pancreatic cancer cell apoptosis.

  2. Low DACH1 expression is associated with invasion of lung adenocarcinoma.

  3. This study concludes that MiR (Montrer MLXIP Anticorps)-217 is the upstream regulator of PGC-1alpha (Montrer PPARGC1A Anticorps) in breast cancer regulation in vitro, possibly independent of DACH1 signaling pathway.

  4. Kaplan-Mier analysis of human NSCLC samples demonstrated that high DACH1 mRNA levels predicted favorable prognosis for relapse-free and overall survival. In agreement, high CXCL5 (Montrer CXCL5 Anticorps) expression predicted a worse prognosis for survival.

  5. DACH1 expression was reduced in hepatocellular carcinoma even at early stage and associated with tumor progression. Overexpression inhibited HCC (Montrer FAM126A Anticorps) cell growth and migration by inactivating the Wnt (Montrer WNT2 Anticorps) pathway via GSK3beta (Montrer GSK3b Anticorps) phosphorylation to suppress beta-catenin (Montrer CTNNB1 Anticorps).

  6. In breast cancer, some GATA3 (Montrer GATA3 Anticorps) effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2 (Montrer BCL2 Anticorps), DACH1, THSD4, representing major GATA3 (Montrer GATA3 Anticorps)-controlled processes in cancer progression.

  7. Results indicated that DACH1 was a novel molecular marker of RCC (Montrer XRCC1 Anticorps) and it attributed to the malignant behavior of renal cancer cells.

  8. Data indicate that dachshund family transcription factor 1 (Montrer HNF1A Anticorps) (DACH1) suppresses gastric cancer cell proliferation, invasion and metastasis by inhibiting transforming growth factor beta (TGF-beta) signalling pathways both in vitro and in vivo.

  9. results suggest that DACH1 loss of function results in increased cell growth, motility and invasiveness through TGF-beta (Montrer TGFB1 Anticorps)-mediated EMT (Montrer ITK Anticorps), and DACH1 loss of function has important therapeutic implications for targeted therapies of CRC (Montrer CALR Anticorps)

  10. DACH1 is a determinant of benign and malignant prostate epithelium cellular growth, migration, and cytokine abundance in vivo.

DACH1 profil antigène

Antigen Summary

This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with DACH1

  • dachshund homolog 1 (Drosophila) (DACH1) anticorps
  • dachshund homolog 1 (dach1) anticorps
  • dachshund d (dachd) anticorps
  • dachshund homolog 1 (Drosophila) (dach1) anticorps
  • dachshund 1 (Drosophila) (Dach1) anticorps
  • AI182278 anticorps
  • Dac anticorps
  • DACH anticorps
  • E130112M23Rik anticorps
  • zgc:158869 anticorps

Protein level used designations for DACH1

dachshund homolog 1 (Drosophila) , dachshund homolog 1 , dachshund 1 , dachshund protein , dachshund homolog 1-like

GENE ID SPECIES
467281 Pan troglodytes
779068 Xenopus laevis
779442 Xenopus (Silurana) tropicalis
791191 Danio rerio
100303544 Saccoglossus kowalevskii
693532 Macaca mulatta
100010972 Monodelphis domestica
100224395 Taeniopygia guttata
100466304 Ailuropoda melanoleuca
100550020 Meleagris gallopavo
100553703 Anolis carolinensis
100595110 Nomascus leucogenys
13134 Mus musculus
1602 Homo sapiens
485489 Canis lupus familiaris
100156238 Sus scrofa
373935 Gallus gallus
100065685 Equus caballus
537184 Bos taurus
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