Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Select your species
The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis.
FOSL2 facilitates TGF-beta1 (Montrer TGFB1 Kits ELISA)-induced migration by interaction with Smad3 (Montrer SMAD3 Kits ELISA) in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 (Montrer TGFB1 Kits ELISA) signalling .
FRA2 is a STAT5 (Montrer STAT5A Kits ELISA) target gene regulated by IL-2 (Montrer IL2 Kits ELISA) in human CD4 (Montrer CD4 Kits ELISA) T cells.
we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 (Montrer FOSB Kits ELISA) transcription factor complex, c-Jun (Montrer JUN Kits ELISA) and Fra2
SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 (Montrer HDAC8 Kits ELISA) in adult T-cell leukemia/lymphoma.
This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease.
results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND (Montrer JUND Kits ELISA) in CCR4 (Montrer CCR4 Kits ELISA)-expressing mature T-cell malignancies such as ATLL and CTCLs
FOSL2 is a critical regulator of leptin (Montrer LEP Kits ELISA) expression in adipocytes
Results suggest that Fra-2 protein may be more effective than ATF-2 (Montrer ATF2 Kits ELISA) protein in cyst formation originated from epithelial cells of dental follicles.
These findings reveal a novel function of Fra-2/AP-1 (Montrer FOSB Kits ELISA) as a positive regulator of bone and matrix formation in mice and humans.
Deletion of Fra-2 leads to increased PPARgamma2 (Montrer PPARG Kits ELISA) expression and adipocyte differentiation as well as increased adipocyte apoptosis through upregulation of hypoxia-inducible factors.
Osteoblast-specific expression of Fra-2/AP-1 (Montrer JUN Kits ELISA) controls adiponectin (Montrer ADIPOQ Kits ELISA) and osteocalcin (Montrer BGLAP Kits ELISA) expression and affects metabolism.
Cytokine-mediated Fra-2 expression and stabilization is linked to regulation of myogenic progenitor cells.
AP-1 (Montrer JUN Kits ELISA) composed with JunD (Montrer JUND Kits ELISA) and Fra2 protein plays a primary role in enhancing the transcription level of the CD11c (Montrer ITGAX Kits ELISA) gene in dendritic cells
Identify Fra-2 as an O(2)-sensitive transcriptional regulator of inducible TGFbeta (Montrer TGFB1 Kits ELISA) expression and position Fra-2 as an important player in reoxygenation-induced myocardial fibrosis.
These findings reveal a novel function of Fra-2/AP-1 (Montrer JUN Kits ELISA) as a positive regulator of bone and matrix formation in mice and humans.
Since transgenic overexpression of Fra-2 causes not only fibrosis but also vascular disease, Fra-2 might be an interesting novel candidate for molecular-targeted therapies for systemic sclerosis.
AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers
Fra2 is a novel transcription factor important for skeletogenesis by affecting chondrocyte differentiation
Fos-like antigen 2 (Fosl2), potentiates the rate of myocardial accretion from the zebrafish second heart field.
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
fos-related antigen 2
, FOS-like antigen 2
, phospholipase B1