Aperçu des produits pour anti-GIGYF2 (GIGYF2) Anticorps

Full name:
anti-GRB10 Interacting GYF Protein 2 Anticorps (GIGYF2)
Chez www.anticorps-enligne.fr sont 15 GRB10 Interacting GYF Protein 2 (GIGYF2) Anticorps de 5 de différents fournisseurs disponibles. De plus, nous expédions GIGYF2 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 24 GIGYF2 produits sont actuellement listés.
Synonymes:
2610016F01Rik, A830080H02Rik, AI852361, AW259676, BC006835, fb57e02, GIGYF2, GYF2, im:6911549, mKIAA0642, PARK11, PERQ2, PERQ3, Tnrc15, wu:fb57e02, zgc:111944
afficher tous les anticorps Gène GeneID UniProt
GIGYF2 26058 Q6Y7W6
GIGYF2 227331 Q6Y7W8
GIGYF2    

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Plus d’anticorps contre GIGYF2 partenaires d’interaction

Human GRB10 Interacting GYF Protein 2 (GIGYF2) interaction partners

  1. Full-length GIGYF2 coimmunoprecipitates with AGO2 (Montrer EIF2C2 Anticorps) in human cells, and upon tethering to a reporter mRNA, GIGYF2 exhibits strong, dose-dependent silencing activity, involving both mRNA destabilization and translational repression.

  2. required, this finding may shed light on the GIGYF2-associated mechanisms that lead to PD and suggests insulin (Montrer INS Anticorps) dysregulation as a disease-specific mechanism for both PD and cognitive dysfunction.

  3. Results suggest that the N56S and N457T of GIGYF2 are risk factors for Parkinson's disease in Caucasians, but not in Asians

  4. GIGYF2 and the zinc finger protein 598 (ZNF598) are identifie (Montrer EIF4E Anticorps)d as components of the 4EHP complex.

  5. Our result indicated that SCNA, LRRK2 (Montrer LRRK2 Anticorps), UCHL1 (Montrer UCHL1 Anticorps), HtrA2 (Montrer HTRA2 Anticorps) and GIGYF2 genes' mutations might not be a main reason for Chinese Autosomal dorminant Parkinson's disease

  6. within the Chinese population, the c.297T>C p.Ala99Ala polymorphism of the GIGYF2 gene may be associated with an increased risk of developing Parkinson disease.

  7. These data, together with those recently reported by other groups, suggest that GIGYF2 is unlikely to be the PARK11 gene.

  8. No clearly pathogenic mutations are identified in GIGYF2 and ATP13A2 (Montrer ATP13A2 Anticorps) in Brazilian patients with early-onset Parkinson's disease.

  9. The results of this study did not support a role for GIGYF2 in the genetic etiology of Belgian Parkinson disease.

  10. GIGYF2 is unlikely to play a major role in PD in Japanese patients, similar to other populations.

Mouse (Murine) GRB10 Interacting GYF Protein 2 (GIGYF2) interaction partners

  1. Negative regulation of Grb10 (Montrer GRB10 Anticorps) Interacting GIGYF2 protein on IGF-1 (Montrer IGF1 Anticorps) receptor signaling pathway caused diabetic mice cognitive impairment.

  2. Disruption of the eukaryotic translation initiation factor 4E (Montrer EIF4E Anticorps) - Gigyf2 complex leads to increased translation and perinatal lethality in mice.

  3. Primary cultured embryo fibroblasts from Gigyf2 null mice exhibit decreased IGF1 (Montrer IGF1 Anticorps) signaling.

  4. identification of proteins linked to insulin (Montrer INS Anticorps)-like growth factor (IGF-I (Montrer IGF1 Anticorps)) receptors by the Grb10 (Montrer GRB10 Anticorps) adapter and modulate IGF-I (Montrer IGF1 Anticorps) signaling

GIGYF2 profil antigène

Antigen Summary

The protein encoded by this gene interacts with GRB10 and may be involved in the regulation of tyrosine kinase receptor signaling. This gene contains CAG repeats, and the encoded protein contains stretches glutamine and glutamic acid residues. Defects in this gene are a cause of Parkinson disease type 11 (PARK11). Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative names and synonyms associated with GIGYF2

  • trinucleotide repeat containing 15 (TNRC15) anticorps
  • GRB10 interacting GYF protein 2 (GIGYF2) anticorps
  • GRB10 interacting GYF protein 2 (Gigyf2) anticorps
  • GRB10 interacting GYF protein 2 (gigfy2) anticorps
  • GRB10 interacting GYF protein 2 (gigyf2) anticorps
  • 2610016F01Rik anticorps
  • A830080H02Rik anticorps
  • AI852361 anticorps
  • AW259676 anticorps
  • BC006835 anticorps
  • fb57e02 anticorps
  • GIGYF2 anticorps
  • GYF2 anticorps
  • im:6911549 anticorps
  • mKIAA0642 anticorps
  • PARK11 anticorps
  • PERQ2 anticorps
  • PERQ3 anticorps
  • Tnrc15 anticorps
  • wu:fb57e02 anticorps
  • zgc:111944 anticorps

Protein level used designations for GIGYF2

trinucleotide repeat containing 15 , GRB10 interacting GYF protein 2 , PERQ amino acid-rich with GYF domain-containing protein 2 , PERQ amino acid rich, with GYF domain 3 , Parkinson disease (autosomal recessive, early onset) 11 , trinucleotide repeat-containing gene 15 protein , GRB10-interacting GYF protein 2

GENE ID SPECIES
424743 Gallus gallus
506913 Bos taurus
612838 Canis lupus familiaris
713675 Macaca mulatta
100021597 Monodelphis domestica
100064814 Equus caballus
100401755 Callithrix jacchus
100439308 Pongo abelii
100547124 Meleagris gallopavo
26058 Homo sapiens
227331 Mus musculus
561830 Danio rerio
495698 Xenopus laevis
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