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anti-Human B4GALT2 Anticorps:
anti-Mouse (Murine) B4GALT2 Anticorps:
anti-Rat (Rattus) B4GALT2 Anticorps:
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Study provides evidence that mutations in B3GNT2 (Montrer B3GNT2 Anticorps), B4GALT2, and ST6GALNAC2 (Montrer ST6GALNAC2 Anticorps) underlie aberrant glycosylation, and contribute to the pathogenesis of molecular subsets of colon and other gastrointestinal malignancies.
Significance of core 2 GlcNAc-T (Montrer GCNT1 Anticorps) in the pathogenesis of capillary occlusion in diabetic retinopathy.
results suggested that beta1,4GalT II might serve as a target gene of p53 (Montrer TP53 Anticorps) transcription factor during adriamycin-induced HeLa cell apoptosis, which elucidated a new mechanism of p53 (Montrer TP53 Anticorps)-mediated cell apoptosis
Data show that Beta4-Gal (Montrer GAL Anticorps)-transferase (beta4GalT) extends core 2 and forms the backbone structure for biologically important epitopes.
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose\; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene.
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2
, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2
, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2
, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2
, beta-1,4-GalTase 2
, beta-1,4-galactosyltransferase 2
, beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2
, beta-1,4-galactosyltransferase II
, Beta-1,4-GalTase 2