Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human FNDC5 Anticorps:
anti-Mouse (Murine) FNDC5 Anticorps:
anti-Rat (Rattus) FNDC5 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Human Polyclonal FNDC5 Primary Antibody pour IF (p), IHC (p) - ABIN1387505
Park, Kim, Choi, Heo, Park: New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro. dans Cellular signalling 2015
Human Polyclonal FNDC5 Primary Antibody pour IHC, IHC (p) - ABIN4327646
Komolka, Albrecht, Schering, Brenmoehl, Hoeflich, Maak: Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? dans PLoS ONE 2014
Human Polyclonal FNDC5 Primary Antibody pour WB - ABIN1169430
Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. dans Cell metabolism 2013
Neither FNDC5 nor its putatively secreted peptide irisin were found in circulation of bulls.
Irisin regulates the number and function of endothelial progenitor cells via the PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps)/eNOS (Montrer NOS3 Anticorps) pathway in mouse model of diabetes mellitus.
there is a correlation between sport performance, insulin (Montrer INS Anticorps) sensitivity, and irisin levels
results firstly revealed that irisin mitigated oxygen-glucose deprivation-induced neuronal injury in part via inhibiting ROS (Montrer ROS1 Anticorps)-NLRP3 (Montrer NLRP3 Anticorps) inflammatory signaling pathway, suggesting a likely mechanism for irisin-induced therapeutic effect in ischemic stroke.
These data indicate that increased irisin levels may have protective roles in liver cancer cells through partial activation of the PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps) pathway, which may facilitate liver cancer progression and decrease the sensitivity to chemotherapy.
Decreased serum irisin levels are related to emphysema in patients with COPD (Montrer ARCN1 Anticorps) and involved in epithelial apoptosis, resulting in emphysema.
Irisin levels are lower in MI and CAD (Montrer CAD Anticorps) implying that their production may depend on myocardial blood supply.
findings suggest that irisin plays an important role in metabolic disorders and may be affected by physiopathological status.
The FNDC5 rs3480 variant is associated with protection from clinically significant (Montrer TSC2 Anticorps) fibrosis in patients with NAFLD, while irisin expression is correlated with the severity of NAFLD and may be involved in extracellular matrix deposition. These data suggest that irisin is involved in regulation of hepatic fibrogenesis.
The median irisin levels were determined higher in T1DM group compared to the control one.
The modulation of body composition and muscle strength induced by 16-week of resistance training in older women with and without obesity is not associated with changes in circulating Irisin levels.
Irisin is upregulated in a murine model of fibrosis, but not in experimental NAFLD (Montrer TSC2 Anticorps) without significant fibrosis.
Irisin improved endothelial function by modulating HO-1 (Montrer HMOX1 Anticorps)/ adiponectin (Montrer ADIPOQ Anticorps) axis in perivascular adipose tissue (PVAT) in HFD-induced obese mice. These findings suggest that regulating PVAT function may be a potential mechanism by which irisin improves endothelial function in obesity.
results are the first to demonstrate that the protective effects of irisin in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (Montrer HDAC5 Anticorps) degradation.
The results indicate that FNDC5 deficiency impairs autophagy and FAO and enhances lipogenesis via the AMPK (Montrer PRKAA1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) pathway. FNDC5 deficiency aggravates whereas FNDC5 overexpression prevents the HFD-induced hyperlipemia, hepatic lipid accumulation, and impaired FAO and autophagy in the liver.
This research is the first to show that irisin modulates macrophage activity by reducing reactive oxygen species (ROS (Montrer ROS1 Anticorps)) overproduction, which could suggest its potential anti-inflammatory properties.
No FNDC5 expression was detected in normal or cancerous stomach tissues. FNDC5 expression in white and brown adipose tissues in the cancer group increased compared with the control and non-cancer groups.
Report showed that irisin suppressed cholesterol synthesis in hepatocytes through the activation of 5' AMP-activated protein kinase (AMPK (Montrer PRKAA2 Anticorps)) and subsequent inhibition of transcription and nuclear translocation of SREBP2 (Montrer SREBF2 Anticorps).
PGC1alpha regulates FNDC5 and its processed and secreted peptide Irisin, which has been proposed to play a critical role in energy expenditure and to promote neural differentiation of mouse embryonic stem cells. Review.
it is concluding that an enhanced expression of Fndc5 in neural progenitor cells is stimulated by Zfp521 (Montrer ZNF521 Anticorps) overexpression in these cells
Irisin directly targets osteoblast, promoting osteoblast proliferation and differentiation via activating P38/ERK MAP kinase (Montrer MAPK1 Anticorps) signaling cascades in vitro.
mouse homolog is linked to myoblast differentiation and development
fibronectin type III domain-containing protein 5
, fibronectin type III domain containing 5
, fibronectin type III repeat-containing protein 2
, peroxisomal protein