Aperçu des produits pour anti-NCOA2 (NCOA2) Anticorps

Full name:
anti-Nuclear Receptor Coactivator 2 Anticorps (NCOA2)
Chez www.anticorps-enligne.fr sont 70 Nuclear Receptor Coactivator 2 (NCOA2) Anticorps de 15 de différents fournisseurs disponibles. De plus, nous expédions NCOA2 Protéines (4) et beaucoup plus de produits pour cette protéine. Un total de 79 NCOA2 produits sont actuellement listés.
Synonymes:
9530095N19, bHLHe75, c-fgr, c-src2, D1Ertd433e, GRIP-1, Grip1, KAT13C, NCoA-2, NCOA2, ncoa2-A, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, SRC-2, SRC2, TIF-2, Tif2, wu:fc41a10, wu:fe26a11, XTIF2

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anti-Human NCOA2 Anticorps:

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anti-NCOA2 Anticorps mieux référencés

  1. Human Polyclonal NCOA2 Primary Antibody pour EIA, WB - ABIN493179 : Mukherjee, Soyal, Fernandez-Valdivia, Gehin, Chambon, Demayo, Lydon, OMalley: Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. dans Molecular and cellular biology 2006 (PubMed)
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  2. Dog (Canine) Monoclonal NCOA2 Primary Antibody pour IF, WB - ABIN968296 : Heery, Kalkhoven, Hoare, Parker: A signature motif in transcriptional co-activators mediates binding to nuclear receptors. dans Nature 1997 (PubMed)
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  3. Human Polyclonal NCOA2 Primary Antibody pour ICC, IF - ABIN151282 : Tognoni, Chadwick, Ackeifi, Tetel: Nuclear receptor coactivators are coexpressed with steroid receptors and regulated by estradiol in mouse brain. dans Neuroendocrinology 2011 (PubMed)
    Show all 3 references for 151282

  4. Human Polyclonal NCOA2 Primary Antibody pour IHC, ELISA - ABIN1450725 : Carapeti, Aguiar, Goldman, Cross: A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. dans Blood 1998 (PubMed)

  5. Cow (Bovine) Polyclonal NCOA2 Primary Antibody pour WB - ABIN2780788 : Strehl, Nebral, König, Harbott, Strobl, Ratei, Struski, Bielorai, Lessard, Zimmermann, Haas, Izraeli: ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

Plus d’anticorps contre NCOA2 partenaires d’interaction

Human Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. T3 promotes differentiation towards chondrocytes-like cells in our in vitro model, that this differentiation is mediated by steroid receptor (Montrer ESR2 Anticorps) co-activator 2 (SRC2) and does not induce hypertrophy

  2. Pancreatic involvement occurs in mesenchymal chondrosarcoma harboring the HEY1 (Montrer HEY1 Anticorps)-NCOA2 gene fusion.

  3. Data suggest that steroid receptor (Montrer ESR2 Anticorps) coactivators (NCOA1 (Montrer NCOA1 Anticorps), NCOA2, NCOA3 (Montrer NCOA3 Anticorps)) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (Montrer ESR2 Anticorps) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  4. SRC-2 may exhibit oncogenic or tumor suppressor activity depending on the target genes and nuclear receptors that are expressed in distinct tissues

  5. NCOA2ETV4 protein would contain the helixloophelix, PAS_9 and PAS_11, CITED domains, the SRC1 (Montrer SRC Anticorps) domain of NCOA2 and the ETS (Montrer ETS1 Anticorps) DNAbinding domain of ETV4 (Montrer ETV4 Anticorps).

  6. Altered expression of TIF2 may play a role in adenomyosis development and treatment outcome with levonorgestrel-releasing intrauterine system.

  7. evaluating if NCOA2 relative copy-number gain presents prognostic value for prostate cancer

  8. Report NcoA2-regulation of the AhR (Montrer AHR Anticorps)-ARNT (Montrer ARNT Anticorps)-HIF-1a (Montrer HIF1A Anticorps) interaction.

  9. Data suggest that LRH1/NR5A2 (Montrer NR5A2 Anticorps) (liver receptor homologue-1) exhibits phospholipid-mediated allosteric control of protein-protein binding interface in interactions with TIF2 and SHP (Montrer LAMC1 Anticorps) (co-repressor; small heterodimer partner (Montrer NR0B2 Anticorps) protein).

  10. NCOA2 is a novel negative growth regulatory gene repressing the Wnt/beta-catenin pathway in colorectal cancer, where recurrent fusion with LACTB2 contributes to its disruption.

Mouse (Murine) Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. the expression of MOZ (Montrer MYST3 Anticorps)-TIF2 fusion protein represses the transcription of p16INK4a (Montrer CDKN2A Anticorps) and p19ARF (Montrer CDKN2A Anticorps) and blocks senescence.

  2. findings position SRC-2 as a major regulator of polygenic inputs to metabolic gene regulation and perhaps identify a previously unappreciated model that helps to explain the clinical spectrum of glucose dysregulation

  3. fetal lungs produce signals to initiate labor when mature, and SRC-1 (Montrer NCOA1 Anticorps)/-2-dependent production of SP-A (Montrer SFTPA1 Anticorps) and PAF (Montrer KIAA0101 Anticorps) is crucial for this process

  4. In a murine model, overexpression of NCoA2 in the prostate epithelium resulted in neoplasia.

  5. the PAX3 (Montrer PAX3 Anticorps)-NCOA2 fusion gene has a dual role in the tumorigenesis of rhabdomyosarcoma

  6. Transcription factor 23 (Tcf23 (Montrer TCF23 Anticorps)), a basic-helix-loop-helix transcription factor (Montrer HEY1 Anticorps), is a new progesterone-induced target gene that requires SRC-2 for full induction.

  7. SRC-2 is a transcriptional coactivator for BMAL1 (Montrer ARNTL Anticorps):CLOCK. Ablation of SRC-2 disrupts the central clock.

  8. SRC-2 is critical to transcriptional control modulated by MEF2 (Montrer MEF2C Anticorps), GATA-4 (Montrer GATA4 Anticorps), and Tbx5 (Montrer TBX5 Anticorps), thereby enhancing gene expression associated with cardiac growth.

  9. SRC2 regulates anxiety response with SRC2(-/-) females showing decreased anxiety in novel environments.

  10. Our results indicate that SRC-2 is involved in maintenance of the steady-state adult heart transcriptional profile, with its ablation inducing transcriptional changes that mimic a stressed heart.

Cow (Bovine) Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. SNP 1718 in the NCOA2 gene was significant for early pregnancy probability (P=0.02) and age at first calving (P=0.03), and SNP 2038 in the same gene was significant for days to calving (P=0.03).

Zebrafish Nuclear Receptor Coactivator 2 (NCOA2) interaction partners

  1. The tif2 is involved in embryogenesis and in primitive hematopoiesis. tif2-knockdown zebrafish embryos are smaller than controls.

NCOA2 profil antigène

Antigen Summary

The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997

Alternative names and synonyms associated with NCOA2

  • nuclear receptor coactivator 2 (NCOA2) anticorps
  • nuclear receptor coactivator 2 (ncoa2) anticorps
  • feline Gardner-Rasheed sarcoma viral oncogene homolog (FGR) anticorps
  • nuclear receptor coactivator 2 (Ncoa2) anticorps
  • 9530095N19 anticorps
  • bHLHe75 anticorps
  • c-fgr anticorps
  • c-src2 anticorps
  • D1Ertd433e anticorps
  • GRIP-1 anticorps
  • Grip1 anticorps
  • KAT13C anticorps
  • NCoA-2 anticorps
  • NCOA2 anticorps
  • ncoa2-A anticorps
  • p55-Fgr anticorps
  • p55c-fgr anticorps
  • p58-Fgr anticorps
  • p58c-fgr anticorps
  • SRC-2 anticorps
  • SRC2 anticorps
  • TIF-2 anticorps
  • Tif2 anticorps
  • wu:fc41a10 anticorps
  • wu:fe26a11 anticorps
  • XTIF2 anticorps

Protein level used designations for NCOA2

nuclear receptor coactivator 2 , Transcriptional intermediary factor 2 , nuclear receptor coactivator 2-like , Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog , c-fgr protooncogene , c-src-2 proto-oncogene , p55-c-fgr protein , proto-oncogene c-Fgr , proto-oncogene tyrosine-protein kinase FGR , tyrosine-protein kinase Fgr , v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog , class E basic helix-loop-helix protein 75 , glucocorticoid receptor-interacting protein-1 , hTIF2 , transcriptional intermediary factor 2 , NCoA-2 , TIF2/GRIP-1 , glucocorticoid receptor interacting protein 1 , glucocorticoid receptor-interacting protein 1 , transcriptional intermediary factor-2 , grip1 , src2 , steroid receptor coactivator 2

GENE ID SPECIES
464226 Pan troglodytes
693455 Macaca mulatta
100028678 Monodelphis domestica
100051656 Equus caballus
100089041 Ornithorhynchus anatinus
100216190 Xenopus (Silurana) tropicalis
100220180 Taeniopygia guttata
100409563 Callithrix jacchus
100458310 Pongo abelii
100468579 Ailuropoda melanoleuca
100567715 Anolis carolinensis
100594525 Nomascus leucogenys
2268 Homo sapiens
10499 Homo sapiens
17978 Mus musculus
83724 Rattus norvegicus
394405 Xenopus laevis
420176 Gallus gallus
486989 Canis lupus familiaris
100135658 Sus scrofa
508162 Bos taurus
81884 Danio rerio
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