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Aperçu des produits pour anti-UBR5 (UBR5) Anticorps

Full name:
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 Anticorps (UBR5)
Chez sont 81 Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions UBR5 Kits (3) et et beaucoup plus de produits pour cette protéine. Un total de 90 UBR5 produits sont actuellement listés.
4432411E13Rik, AW549941, C77315, D030042K14, Dd5, Edd, Edd1, HYD, mKIAA0896, Rat100

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anti-Human UBR5 Anticorps:

anti-Mouse (Murine) UBR5 Anticorps:

anti-Rat (Rattus) UBR5 Anticorps:

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anti-UBR5 Anticorps mieux référencés

  1. Human Polyclonal UBR5 Primary Antibody pour ICC, IF - ABIN151138 : Nash, Chen, Salganik, Muzyczka: Identification of cellular proteins that interact with the adeno-associated virus rep protein. dans Journal of virology 2008 (PubMed)
    Show all 7 references for ABIN151138

  2. Human Polyclonal UBR5 Primary Antibody pour IHC (p), IHC - ABIN249850 : Garbow, Doherty, Schugar, Travers, Weber, Wentz, Ezenwajiaku, Cotter, Brunt, Crawford: Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet. dans American journal of physiology. Gastrointestinal and liver physiology 2011 (PubMed)
    Show all 2 references for ABIN249850

  3. Cow (Bovine) Polyclonal UBR5 Primary Antibody pour EIA, IHC (p) - ABIN1109445 : Hay-Koren, Caspi, Zilberberg, Rosin-Arbesfeld: The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin. dans Molecular biology of the cell 2011 (PubMed)

  4. Human Polyclonal UBR5 Primary Antibody pour IHC, ELISA - ABIN184976 : Henderson, Russell, Hird, Muñoz, Clancy, Lehrbach, Calanni, Jans, Sutherland, Watts: EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response. dans The Journal of biological chemistry 2002 (PubMed)

Plus d’anticorps contre UBR5 partenaires d’interaction

Human Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) interaction partners

  1. Data show that ubiquitin protein ligase E3 component n-recognin 5 protein (UBR5) bound the tumor suppressor gastrokine 1 (GKN1 (Montrer GKN1 Anticorps)) and increased its ubiquitination to reduce the protein stability of GKN1 (Montrer GKN1 Anticorps).

  2. Findings unveil UBR5 as a novel and critical regulator of tumor growth, metastasis, and immune response in triple negative breast cancer.

  3. Study highlights many functional biological role of UBR5 especially in cancer where it seems to be a key regulator of cell signaling. [review]

  4. Colony-formation assays and soft agar assays show that gain of function of TIP60 or depletion of EDD1 in HPV-positive cervical cancer cells significantly inhibits cell growth in vitro

  5. Human herpesvirus-6 U14 induces cell cycle arrest in G2/M phase by associating with a cellular protein, EDD.

  6. Elevated metaphase RanGTP levels use Ubr5 to couple overall chromosome congression to SAC (Montrer ADCY10 Anticorps) silencing.

  7. results confirm the role of the MLLE domain of UBR5 in substrate recruitment and suggest a potential role in regulating UBR5 ligase activity.

  8. these observations highlight the potential role of EDD in regulating mitotic progression and the cellular response to perturbed mitosis.

  9. Utilizing a high throughput RNAi screening approach author identified UBR5, a protein commonly amplified in breast cancer, as a novel regulator of ERalpha (Montrer ESR1 Anticorps) protein levels and transcriptional activity.

  10. the alpha4 N-terminus binding to endogenous PP2Ac (Montrer PPP2CA Anticorps) and PABP (Montrer PABPC1 Anticorps), and the C-terminus to EDD, is reported.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) interaction partners

  1. Findings unveil UBR5 as a novel and critical regulator of tumor growth, metastasis, and immune response in triple negative breast cancer.

  2. UBR5-mediated ATMIN (Montrer ATMIN Anticorps) ubiquitination is a vital event for ATM (Montrer ATM Anticorps) pathway selection and activation in response to DNA damage

  3. a novel function of RIP1 (Montrer RALBP1 Anticorps) kinase involving its interaction with EDD to regulate JNK (Montrer MAPK8 Anticorps) activation and TNFalpha (Montrer TNF Anticorps) production.

  4. Silencing Edd1 with shRNA in mouse embryonic stem cells significantly suppressed their growth.

  5. The SCF (Montrer KITLG Anticorps) E3 ligase complex containing Fbxo40 (Montrer FBXO40 Anticorps) directly ubiquitinates IRS1 (Montrer IRS1 Anticorps), and this activity is enhanced by increased tyrosine phosphorylation of IRS1 (Montrer IRS1 Anticorps).

  6. Through the PABC domain, EDD participates in miRNA silencing by recruiting downstream effectors.

  7. UBR5 can attenuate myocardin (Montrer MYOCD Anticorps) protein degradation resulting in increased myocardin (Montrer MYOCD Anticorps) protein expression without affecting myocardin (Montrer MYOCD Anticorps) mRNA expression.

  8. Results suggest that Edd has an essential role in extraembryonic development.

UBR5 profil antigène

Antigen Summary

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Alternative names and synonyms associated with UBR5

  • ubiquitin protein ligase E3 component n-recognin 5 (UBR5) anticorps
  • ubiquitin protein ligase E3 component n-recognin 5 (Ubr5) anticorps
  • 4432411E13Rik anticorps
  • AW549941 anticorps
  • C77315 anticorps
  • D030042K14 anticorps
  • Dd5 anticorps
  • Edd anticorps
  • Edd1 anticorps
  • HYD anticorps
  • mKIAA0896 anticorps
  • Rat100 anticorps

Protein level used designations for UBR5

E3 identified by differential display , E3 ubiquitin protein ligase, HECT domain containing, 1 , E3 ubiquitin-protein ligase UBR5 , E3 ubiquitin-protein ligase, HECT domain-containing 1 , hHYD , hyperplastic discs protein homolog , progestin induced protein , progestin-induced protein , ubiquitin-protein ligase , extraembryonic development

51366 Homo sapiens
70790 Mus musculus
117060 Rattus norvegicus
420252 Gallus gallus
475055 Canis lupus familiaris
100157625 Sus scrofa
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