Aperçu des produits pour anti-NEK2 (NEK2) Anticorps

Full name:
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 Anticorps (NEK2)
Chez www.anticorps-enligne.fr sont 164 NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions NEK2 Protéines (11) et NEK2 Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 187 NEK2 produits sont actuellement listés.
Synonymes:
AA617254, ATNEK2, C77054, HsPK21, NEK2A, NIMA-RELATED KINASE2, NIMA-related kinase 2, NLK1, T9J14.24, T9J14_24

Réactivités les plus populaires pour anti-NEK2 (NEK2) Anticorps

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anti-Mouse (Murine) NEK2 Anticorps:

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anti-NEK2 Anticorps mieux référencés

  1. Human Polyclonal NEK2 Primary Antibody pour WB - ABIN392650 : Chen, Riley, Zheng, Chen, Lee: Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. dans The Journal of biological chemistry 2002 (PubMed)
    Show all 6 references for 392650

  2. Human Polyclonal NEK2 Primary Antibody pour EIA, WB - ABIN360538 : Eto, Elliott, Prickett, Brautigan: Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation. dans The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for 360538

  3. Human Monoclonal NEK2 Primary Antibody pour ICFC - ABIN2666354 : Hames, Fry: Alternative splice variants of the human centrosome kinase Nek2 exhibit distinct patterns of expression in mitosis. dans The Biochemical journal 2001 (PubMed)
    Show all 3 references for 2666354

  4. Human Polyclonal NEK2 Primary Antibody pour IF (p), IHC (p) - ABIN713921 : Zhong, Guan, Dong, Yang, Liu, Zhang: Examining Nek2 as a better proliferation marker in non-small cell lung cancer prognosis. dans Tumour biology 2014 (PubMed)
    Show all 3 references for 713921

  5. Human Monoclonal NEK2 Primary Antibody pour IHC (f), IF - ABIN968053 : Fry, Schultz, Bartek, Nigg: Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans. dans The Journal of biological chemistry 1995 (PubMed)
    Show all 2 references for 968053

  6. Human Polyclonal NEK2 Primary Antibody pour EIA, WB - ABIN360537 : Cantrell: Phosphoinositide 3-kinase signalling pathways. dans Journal of cell science 2001 (PubMed)

  7. Human Polyclonal NEK2 Primary Antibody pour WB - ABIN392649 : Blume-Jensen, Hunter: Oncogenic kinase signalling. dans Nature 2001 (PubMed)

Plus d’anticorps contre NEK2 partenaires d’interaction

Mouse (Murine) NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) interaction partners

  1. Cep85 is a bona fide Nek2A-binding partner that surrounds the proximal ends of centrioles where it cooperates with PP1gamma (also known as PPP1CC (Montrer PPP1CC Anticorps)) to antagonize Nek2A

  2. The results suggest that overexpression of NEK2 has the potential to serve as a biomarker for PCa (Montrer ENPP1 Anticorps) prognosis.

  3. Nek2 transgenic mice develop spontaneous germinal centers and exhibit an enhanced T cell dependent immune response our data demonstrates a novel role for Nek2 in regulating B cell development and the immune response

  4. these data indicate that Nek2 has a pivotal role in breast cancer growth at primary and secondary sites, and thus may be an attractive and novel therapeutic target for this disease.

  5. CIP2A (Montrer KIAA1524 Anticorps) strongly interacts with NEK2 during G2/M phase, thereby enhancing NEK2 kinase activity to facilitate centrosome separation in a PP1 (Montrer PPP1CC Anticorps)- and PP2A (Montrer PPP2R2B Anticorps)-independent manner.

  6. Nek2 and its substrate, centrobin/Nip2, are required for proper meiotic spindle formation of the mouse oocytes

  7. Data show that NEK2 was identified as a tumor-associated antigen.

  8. Nek2 may be a mitotic regulator that is involved in diverse cell cycle events.

  9. Tcp10 promoter-directed expression of the Nek2 gene in mouse meiotic spermatocytes.

  10. The MAPK (Montrer MAPK1 Anticorps) pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes.

Human NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) interaction partners

  1. NEK2 modulates hepatoma cell functions, including growth, drug resistance, metastasis and angiogenesis via downstream genes activation

  2. Alteration of NEK2 protein levels may contribute to invasion and metastasis of hepatocellular carcinoma

  3. the functional roles of NEK2 in cancer development (review)

  4. NEK2 was associated with unfavorable outcomes in HCC (Montrer FAM126A Anticorps) patients.

  5. enhanced NEK2 expression in hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)) promotes HCC (Montrer FAM126A Anticorps) progression and drug resistance by promoting PP1 (Montrer PPA1 Anticorps)/Akt (Montrer AKT1 Anticorps) and Wnt (Montrer WNT2 Anticorps) pathway activation, which may represent a new therapeutic target for HCC (Montrer FAM126A Anticorps).

  6. Our findings demonstrated that NEK2 could be a valuable carcinogenic factor and a promising therapeutic target for primary liver cancer

  7. Suggest elevated Nek2 protein expression may be an independent risk factor for colon cancer.

  8. Hepatocellular carcinoma patients with high NEK2 expression had significantly poor recurrence-free survival (p=0.042) and early recurrence after hepatectomy.

  9. Cep85 is a bona fide Nek2A-binding partner that surrounds the proximal ends of centrioles where it cooperates with PP1gamma (also known as PPP1CC (Montrer PPP1CC Anticorps)) to antagonize Nek2A

  10. Kif24 (Montrer KIF24 Anticorps) is a physiological substrate of Nek2, which regulates cilia disassembly through a concerted mechanism involving Kif24 (Montrer KIF24 Anticorps)-mediated microtubule depolymerization.

NEK2 profil antigène

Antigen Summary

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.

Alternative names and synonyms associated with NEK2

  • NIMA (never in mitosis gene a)-related kinase 2 (NEK2) anticorps
  • NIMA (never in mitosis gene a)-related expressed kinase 2 (Nek2) anticorps
  • NIMA-related kinase 2 (NEK2) anticorps
  • serine/threonine-protein kinase Nek2 (NEK2) anticorps
  • AA617254 anticorps
  • ATNEK2 anticorps
  • C77054 anticorps
  • HsPK21 anticorps
  • NEK2A anticorps
  • NIMA-RELATED KINASE2 anticorps
  • NIMA-related kinase 2 anticorps
  • NLK1 anticorps
  • T9J14.24 anticorps
  • T9J14_24 anticorps

Protein level used designations for NEK2

NIMA (never in mitosis gene a)-related kinase 2 , NIMA - related expressed kinase 2 , NIMA-related expressed kinase 2 , NIMA-related kinase 2 , Nek2 kinase , never in mitosis A-related kinase 2 , nimA-related protein kinase 2 , serine/threonine-protein kinase Nek2 , serine/threonine protein kinase Nek2 , nimA-like protein kinase 1

GENE ID SPECIES
100540058 Meleagris gallopavo
18005 Mus musculus
114482 Rattus norvegicus
480021 Canis lupus familiaris
397258 Sus scrofa
523998 Bos taurus
4751 Homo sapiens
819641 Arabidopsis thaliana
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