Aperçu des produits pour anti-RAB8A (RAB8A) Anticorps

Full name:
anti-RAB8A, Member RAS Oncogene Family Anticorps (RAB8A)
Chez www.anticorps-enligne.fr sont 86 RAB8A, Member RAS Oncogene Family (RAB8A) Anticorps de 19 de différents fournisseurs disponibles. De plus, nous expédions RAB8A Protéines (16) et RAB8A Kits (9) et beaucoup plus de produits pour cette protéine. Un total de 115 RAB8A produits sont actuellement listés.
Synonymes:
AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, Mel, Rab8, rab8A, zgc:162699

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anti-Human RAB8A Anticorps:

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anti-RAB8A Anticorps mieux référencés

  1. Dog (Canine) Monoclonal RAB8A Primary Antibody pour IF, IP - ABIN968210 : Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. dans The Journal of cell biology 2001 (PubMed)
    Show all 5 references for 968210

  2. Human Polyclonal RAB8A Primary Antibody pour FACS, IHC (p) - ABIN1881723 : Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. dans Gene 1995 (PubMed)
    Show all 2 references for 1881723

  3. Human Polyclonal RAB8A Primary Antibody pour ELISA, WB - ABIN238664 : Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. dans The Journal of cell biology 2007 (PubMed)

  4. Cow (Bovine) Polyclonal RAB8A Primary Antibody pour WB - ABIN2792290 : Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. dans Molecular biology of the cell 2007 (PubMed)

Plus d’anticorps contre RAB8A partenaires d’interaction

Human RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. GRAF1 (Montrer ARHGAP26 Anticorps)-mediated removal of Rab8 from the cell surface restricts its activity during protrusion formation, thereby facilitating dynamic adjustment of the polarity axis.

  2. the TNPO1 (Montrer TNPO1 Anticorps)-Rab8-ciliary targeting signals complex mediates selective entry into and retention of cargos within cilia.

  3. Ectopic expression of an N-terminal-truncated ARHGEF10 (Montrer ARHGEF10 Anticorps) mutant led to the generation of large vesicle-like structures containing both Rab6 (Montrer RAB6A Anticorps) and Rab8.

  4. report the design of a bioavailable StRIP3 analogue that harbors two hydrophobic cross-links and exhibits increased binding affinity, combined with robust cellular uptake and extremely high proteolytic stability. Localization experiments reveal that this double-stapled peptide and its target protein Rab8a accumulate in the same cellular compartments

  5. knockdown of another Parkinson's disease (PD) gene, LRRK2 (Montrer LRRK2 Anticorps), which phosphorylates Rab8a, similarly impairs retromer trafficking, secretory autophagy and Golgi-derived vesicle secretion, thus demonstrating converging roles of two PD genes TMEM230 and LRRK2 (Montrer LRRK2 Anticorps) on Rab8a function, and suggesting that retromer and secretory dysfunction play an important role in PD pathogenesis.

  6. Rab8 can induce Rac1- and Tiam1 (Montrer TIAM1 Anticorps)-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (Montrer MMP14 Anticorps) and calpain, and Rho-GTPase (Montrer RACGAP1 Anticorps)-dependent mechanisms

  7. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (Montrer BIN1 Anticorps)-dynamin (Montrer DNM1 Anticorps) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  8. Further exploration of the NINL (Montrer NINL Anticorps)-associated interactome identifies MICAL3 (Montrer MICAL3 Anticorps), a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  9. The small GTPase (Montrer RACGAP1 Anticorps) Rab8 interacts with VAMP-3 (Montrer VAMP3 Anticorps) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  10. the role of Rabin8 (Montrer RAB3IP Anticorps) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Cc2d2a (Montrer CC2D2A Anticorps), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (Montrer TRAF3IP1 Anticorps) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (Montrer RACGAP1 Anticorps), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Rab8a and Rab11a (Montrer RAB11A Anticorps) Are Dispensable for Rhodopsin (Montrer RHO Anticorps) Transport in Mouse Photoreceptors

  2. With CRISPR/Cas9-mediated gene editing to stably knock out and recover Rab8a in macrophage cell lines, this study matches Akt (Montrer AKT1 Anticorps) signaling profiles with cytokine outputs, confirming that Rab8a is a novel regulator of the Akt (Montrer AKT1 Anticorps)/mammalian target of rapamycin (mTOR (Montrer FRAP1 Anticorps)) pathway downstream of multiple Toll (Montrer TLR4 Anticorps)-like Receptors.

  3. these results indicate an indispensable role for Rab8A in insulin (Montrer INS Anticorps)-regulated GLUT4 (Montrer SLC2A4 Anticorps) trafficking in C2C12 cells.

  4. Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.

  5. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (Montrer BIN1 Anticorps)-dynamin (Montrer DNM1 Anticorps) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  6. The small GTPase (Montrer RACGAP1 Anticorps) Rab8 interacts with VAMP-3 (Montrer VAMP3 Anticorps) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  7. Rab8a thus controls Wnt (Montrer WNT2 Anticorps) delivery in producing cells and is crucial for Paneth cell maturation.

  8. Rab8a acts as an activator of Fsp27 (Montrer CIDEC Anticorps)-mediated LD fusion and growth.

  9. Simultaneous loss of Rab8a and Rab8b (Montrer RAB8B Anticorps) has little effect on ciliogenesis, whereas additional loss of Rab10 (Montrer RAB10 Anticorps) greatly affects ciliogenesis.

  10. acidosis-induced NBCe1 (Montrer SLC4A4 Anticorps)-A, but not NBCe1 (Montrer SLC4A4 Anticorps)-B/C, trafficking is mediated by Rab8a.

RAB8A profil antigène

Antigen Summary

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Alternative names and synonyms associated with RAB8A

  • rab8A protein (rab8A) anticorps
  • Rab GTPase (rab8A) anticorps
  • RAB8A, member RAS oncogene family (RAB8A) anticorps
  • RAB8A, member RAS oncogene family (rab8a) anticorps
  • RAB8A, member RAS oncogene family (Rab8a) anticorps
  • AA409338 anticorps
  • c-mel anticorps
  • DDBDRAFT_0206521 anticorps
  • DDBDRAFT_0214885 anticorps
  • DDB_0206521 anticorps
  • DDB_0214885 anticorps
  • HSH2D anticorps
  • Mel anticorps
  • Rab8 anticorps
  • rab8A anticorps
  • zgc:162699 anticorps

Protein level used designations for RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPECIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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