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Hhex (Montrer HHEX Kits ELISA) and Cer1 are indispensable components of the Sox17 (Montrer SOX17 Kits ELISA) pathway for cardiopoiesis.
regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus and the Baf60c/Smarcd3 subunit of the Brg1/Brm-associated factors (BAF) chromatin-remodelling complex
a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS cells
Role of Cerberus-like in mouse embryogenesis
Cerberus-like and Lefty-1 (Montrer LEFTY1 Kits ELISA) function redundantly to modulate Nodal signaling during gastrulation and regulate patterning of the primitive streak
Some early Cer1-expressing cells do contribute to the AVE when it becomes established at E5.5.
successful identification of an association with CER1 in humans together with our mouse study suggests that CER1 may play a role in the development of bone or its metabolism
Cerberus binds and inhibits Nodal, Activin B (Montrer Actbeta Kits ELISA), BMP-6 (Montrer BMP6 Kits ELISA), and BMP-7 (Montrer BMP7 Kits ELISA) but not BMP-2 (Montrer BMP2 Kits ELISA) or Activin A (Montrer INHBA Kits ELISA).
No significant association between the studied DKK1 (Montrer DKK1 Kits ELISA) variations and osteoporosis was found, while CER1 variations seem to play a significant role in the determination of osteoporosis, combined with bone markers, in postmenopausal osteoporotic women.
results show that Cer1 (or CER1) serves as a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS (Montrer SLC27A4 Kits ELISA) cells
CER1 gene variations play a significant role in determining BMD (Montrer BEST1 Kits ELISA) and vertebral or hip fractures, which might be helpful in clinical practice to identify patients with increased fracture risk
Chordin (Montrer CHRD Kits ELISA), Noggin (Montrer NOG Kits ELISA), beta-Catenin (Montrer CTNNB1 Kits ELISA), and Cerberus have roles in neural induction in Xenopus
Cardiogenesis in mesoderm depends on Nodal-mediated induction of Cerberus in underlying endoderm.
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.
cerberus-related protein 1
, cerberus 1, cysteine knot superfamily
, cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
, cerberus 1, cysteine knot superfamily, homolog
, Cerberus-related protein
, U-box protein
, cerberus homolog
, cerberus-like protein
, cerberus-related protein
, cerberus 1 homolog, cysteine knot superfamily
, DAN domain family member 4
, cerberus-related 1